UA41915C2 - Засіб для інгібування проліферації і міграції клітин васкулярних гладенькіх м`язів у ссавців - Google Patents

Засіб для інгібування проліферації і міграції клітин васкулярних гладенькіх м`язів у ссавців

Info

Publication number
UA41915C2
UA41915C2 UA95083997A UA95083997A UA41915C2 UA 41915 C2 UA41915 C2 UA 41915C2 UA 95083997 A UA95083997 A UA 95083997A UA 95083997 A UA95083997 A UA 95083997A UA 41915 C2 UA41915 C2 UA 41915C2
Authority
UA
Ukraine
Prior art keywords
mammals
migration
agent
vascular smooth
inhibiting proliferation
Prior art date
Application number
UA95083997A
Other languages
English (en)
Russian (ru)
Inventor
Іліот Х. ОЛСТАЙН
Илиот Х. Олстайн
Original Assignee
Боерінгер Маннхайм Фармасьютікалз Корпорейшн-Смітклайн Бічам Корпорейшн Лімітед Партнершіп №1
Берингер Маннхайм Фармасьютикалз Корпорейшн-Смитклайн Бичам Корпорейшн Лимитед Партнершип №1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/026,892 external-priority patent/US5308862A/en
Application filed by Боерінгер Маннхайм Фармасьютікалз Корпорейшн-Смітклайн Бічам Корпорейшн Лімітед Партнершіп №1, Берингер Маннхайм Фармасьютикалз Корпорейшн-Смитклайн Бичам Корпорейшн Лимитед Партнершип №1 filed Critical Боерінгер Маннхайм Фармасьютікалз Корпорейшн-Смітклайн Бічам Корпорейшн Лімітед Партнершіп №1
Publication of UA41915C2 publication Critical patent/UA41915C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Застосування сполуки карведилолу формули як засобу для інгібування проліферації і міграції клітин васкулярних гладеньких м'язів у ссавців.
UA95083997A 1993-03-05 1993-08-27 Засіб для інгібування проліферації і міграції клітин васкулярних гладенькіх м`язів у ссавців UA41915C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/026,892 US5308862A (en) 1993-03-05 1993-03-05 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
PCT/US1993/002062 WO1994020096A1 (en) 1993-03-05 1993-03-05 Method of employing carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
PCT/US1993/008019 WO1994020097A1 (en) 1993-03-05 1993-08-27 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
UA41915C2 true UA41915C2 (uk) 2001-10-15

Family

ID=26701782

Family Applications (1)

Application Number Title Priority Date Filing Date
UA95083997A UA41915C2 (uk) 1993-03-05 1993-08-27 Засіб для інгібування проліферації і міграції клітин васкулярних гладенькіх м`язів у ссавців

Country Status (7)

Country Link
EP (1) EP0746315A4 (uk)
JP (1) JPH08508013A (uk)
AU (1) AU679462B2 (uk)
NO (1) NO307865B1 (uk)
RU (1) RU2147433C1 (uk)
UA (1) UA41915C2 (uk)
WO (2) WO1994020096A1 (uk)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
US4970227A (en) * 1984-11-20 1990-11-13 Burroughs Wellcome Co. Carbazole derivatives

Also Published As

Publication number Publication date
EP0746315A4 (en) 1999-01-07
NO953480L (no) 1995-11-03
NO953480D0 (no) 1995-09-04
AU5092393A (en) 1994-09-26
JPH08508013A (ja) 1996-08-27
WO1994020096A1 (en) 1994-09-15
WO1994020097A1 (en) 1994-09-15
RU2147433C1 (ru) 2000-04-20
NO307865B1 (no) 2000-06-13
AU679462B2 (en) 1997-07-03
EP0746315A1 (en) 1996-12-11

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