ZA878590B - Pyrrolo benzimidazoles,pharmaceutical compositions containing these compounds and processes for their preparation - Google Patents

Pyrrolo benzimidazoles,pharmaceutical compositions containing these compounds and processes for their preparation

Info

Publication number
ZA878590B
ZA878590B ZA878590A ZA878590A ZA878590B ZA 878590 B ZA878590 B ZA 878590B ZA 878590 A ZA878590 A ZA 878590A ZA 878590 A ZA878590 A ZA 878590A ZA 878590 B ZA878590 B ZA 878590B
Authority
ZA
South Africa
Prior art keywords
benzimidazoles
pyrrolo
compounds
processes
preparation
Prior art date
Application number
ZA878590A
Other languages
English (en)
Inventor
Berthold Narr
Narr Berthold
Norbert Hauel
Hauel Norbert
Klaus Noll
Noll Klaus
Joachim Heider
Heider Joachim
Manfred Psiorz
Psiorz Manfred
Andreas Bomhard
Bomhard Andreas
Jacques Van Meel
Van Meel Jacques
Willi Diederen
Diederen Willi
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA878590B publication Critical patent/ZA878590B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA878590A 1986-11-18 1987-11-17 Pyrrolo benzimidazoles,pharmaceutical compositions containing these compounds and processes for their preparation ZA878590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863639466 DE3639466A1 (de) 1986-11-18 1986-11-18 Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA878590B true ZA878590B (en) 1989-07-26

Family

ID=6314255

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878590A ZA878590B (en) 1986-11-18 1987-11-17 Pyrrolo benzimidazoles,pharmaceutical compositions containing these compounds and processes for their preparation

Country Status (14)

Country Link
EP (1) EP0268178A1 (da)
JP (1) JPS63135385A (da)
KR (1) KR890003688A (da)
AU (1) AU8129987A (da)
DD (1) DD272081A5 (da)
DE (1) DE3639466A1 (da)
DK (1) DK602487A (da)
FI (1) FI875076A (da)
HU (1) HUT47277A (da)
IE (1) IE873089L (da)
IL (1) IL84509A0 (da)
NO (1) NO874780L (da)
PT (1) PT86154B (da)
ZA (1) ZA878590B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3803775A1 (de) * 1988-02-09 1989-08-17 Boehringer Mannheim Gmbh Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE3932953A1 (de) * 1989-10-03 1991-04-11 Boehringer Mannheim Gmbh Neue 2-bicyclo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
EP1598353A1 (en) * 2004-05-17 2005-11-23 Boehringer Ingelheim International GmbH Pyrrolobenzimidazolones and their use as antiproliferative agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL144822B1 (en) * 1984-05-12 1988-07-30 Boehringer Mannheim Gmbh Method of obtaining novel pyrolobenzimidazoles
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte

Also Published As

Publication number Publication date
IL84509A0 (en) 1988-04-29
AU8129987A (en) 1988-05-19
JPS63135385A (ja) 1988-06-07
NO874780L (no) 1988-05-19
FI875076A (fi) 1988-05-19
KR890003688A (ko) 1989-04-17
DE3639466A1 (de) 1988-05-19
FI875076A0 (fi) 1987-11-17
EP0268178A1 (de) 1988-05-25
PT86154A (de) 1987-12-01
DD272081A5 (de) 1989-09-27
PT86154B (pt) 1990-11-20
DK602487A (da) 1988-05-19
IE873089L (en) 1988-05-18
DK602487D0 (da) 1987-11-17
NO874780D0 (no) 1987-11-17
HUT47277A (en) 1989-02-28

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