ZA877987B - Antibiotic compounds - Google Patents

Antibiotic compounds

Info

Publication number
ZA877987B
ZA877987B ZA877987A ZA877987A ZA877987B ZA 877987 B ZA877987 B ZA 877987B ZA 877987 A ZA877987 A ZA 877987A ZA 877987 A ZA877987 A ZA 877987A ZA 877987 B ZA877987 B ZA 877987B
Authority
ZA
South Africa
Prior art keywords
antibiotic compounds
antibiotic
compounds
Prior art date
Application number
ZA877987A
Other languages
English (en)
Inventor
Alain Michel Bertrandie
Michel Bertrandie Alain
Frederic Henri Jung
Henri Jung Frederic
Jean-Jacques Marcel Lohmann
Marcel Lohmann Jean-Jacques
Thomas Geoffrey Colerick Bird
Geoffrey Colerick Bird Thomas
Original Assignee
Ici Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma filed Critical Ici Pharma
Publication of ZA877987B publication Critical patent/ZA877987B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA877987A 1986-11-12 1987-10-23 Antibiotic compounds ZA877987B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP86402515 1986-11-12

Publications (1)

Publication Number Publication Date
ZA877987B true ZA877987B (en) 1988-08-31

Family

ID=8196357

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA877987A ZA877987B (en) 1986-11-12 1987-10-23 Antibiotic compounds

Country Status (15)

Country Link
US (1) US5017569A (de)
EP (1) EP0267733A3 (de)
JP (1) JPS63211288A (de)
AU (1) AU612990B2 (de)
DD (1) DD282691A5 (de)
DK (1) DK591887A (de)
FI (1) FI874939A (de)
HU (1) HU202541B (de)
IE (1) IE873037L (de)
MW (1) MW7687A1 (de)
NO (1) NO874690L (de)
NZ (1) NZ222407A (de)
PT (1) PT86125B (de)
ZA (1) ZA877987B (de)
ZW (1) ZW19487A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2621589B1 (fr) * 1987-10-08 1990-03-02 Sanofi Sa Derives des cephalosporines a pharmacocinetique amelioree, procede pour leur preparation et compositions pharmaceutiques les contenant
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds
YU63689A (en) * 1988-03-31 1991-06-30 Hoffmann La Roche Acyl derivatives
EP0341990B1 (de) * 1988-05-10 1994-11-09 Imperial Chemical Industries Plc Cephalosporine, Verfahren zu ihrer Herstellung und pharmazeutische Präparate
GB8811055D0 (en) * 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
GB8811056D0 (en) * 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
EP0344707A3 (de) * 1988-06-02 1990-04-18 E.R. Squibb & Sons, Inc. 2-Oxo-1-[[(substituiertes sulfony)-amino]carbonyl]-Azetidinderivate
PH25965A (en) * 1988-06-06 1992-01-13 Fujisawa Pharmaceutical Co New cephem compounds which have antimicrobial activities
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
US5194604A (en) * 1990-06-29 1993-03-16 E. R. Squibb & Sons, Inc. Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains
AP199A (en) * 1991-05-28 1992-06-30 Beecham Group Plc Novel B-Lactam and a novel class cephalosporins.
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
DE19654920A1 (de) * 1996-06-26 1998-01-08 Gruenenthal Gmbh Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1496757A (en) * 1973-12-21 1978-01-05 Glaxo Lab Ltd Cephalosporin derivatives
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
US4379920A (en) * 1979-10-31 1983-04-12 Glaxo Group Limited Cephalosporins
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
FR2570702B1 (fr) * 1984-09-27 1987-01-09 Sanofi Sa Derives des cephalosporines, procedes d'obtention et leur application a titre d'antibiotiques
DE3581891D1 (de) * 1984-11-12 1991-04-04 Banyu Pharma Co Ltd Cephalosporinderivate.
ES8704943A1 (es) * 1984-12-27 1987-04-16 Banyu Pharma Co Ltd Un procedimiento para la fabricacion de derivados de cefalosporina.
CA1296012C (en) * 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
DE3750411T2 (de) * 1986-04-14 1995-03-16 Banyu Pharma Co Ltd Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate.
EP0265185A3 (de) * 1986-10-21 1990-03-28 Beecham Group Plc Cephalosporine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
ZA884093B (en) * 1987-06-16 1989-04-26 Hoffmann La Roche Acyl derivatives
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds

Also Published As

Publication number Publication date
EP0267733A3 (de) 1989-11-29
MW7687A1 (en) 1988-07-13
FI874939A (fi) 1988-05-13
EP0267733A2 (de) 1988-05-18
HU202541B (en) 1991-03-28
DK591887A (da) 1988-05-13
NO874690L (no) 1988-05-13
ZW19487A1 (en) 1989-05-31
PT86125A (en) 1987-12-01
AU612990B2 (en) 1991-07-25
DD282691A5 (de) 1990-09-19
PT86125B (pt) 1990-11-20
IE873037L (en) 1988-05-12
DK591887D0 (da) 1987-11-11
NZ222407A (en) 1989-05-29
FI874939A0 (fi) 1987-11-09
US5017569A (en) 1991-05-21
NO874690D0 (no) 1987-11-11
JPS63211288A (ja) 1988-09-02
HUT46021A (en) 1988-09-28
AU8092687A (en) 1988-05-19

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