ZA876276B - (5r,6s,8r)-6-(1-hydroxyethyl)-2-(3r-pyrrolidin-2-one-3-yl)thiopenem-3-carboxylic acid - Google Patents

(5r,6s,8r)-6-(1-hydroxyethyl)-2-(3r-pyrrolidin-2-one-3-yl)thiopenem-3-carboxylic acid

Info

Publication number
ZA876276B
ZA876276B ZA876276A ZA876276A ZA876276B ZA 876276 B ZA876276 B ZA 876276B ZA 876276 A ZA876276 A ZA 876276A ZA 876276 A ZA876276 A ZA 876276A ZA 876276 B ZA876276 B ZA 876276B
Authority
ZA
South Africa
Prior art keywords
thiopenem
pyrrolidin
hydroxyethyl
carboxylic acid
carboxylic
Prior art date
Application number
ZA876276A
Other languages
English (en)
Inventor
W. Mccombie Stuart
R. Tagat Jayaram
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of ZA876276B publication Critical patent/ZA876276B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA876276A 1986-08-25 1987-08-24 (5r,6s,8r)-6-(1-hydroxyethyl)-2-(3r-pyrrolidin-2-one-3-yl)thiopenem-3-carboxylic acid ZA876276B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90006686A 1986-08-25 1986-08-25

Publications (1)

Publication Number Publication Date
ZA876276B true ZA876276B (en) 1988-02-24

Family

ID=25411927

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876276A ZA876276B (en) 1986-08-25 1987-08-24 (5r,6s,8r)-6-(1-hydroxyethyl)-2-(3r-pyrrolidin-2-one-3-yl)thiopenem-3-carboxylic acid

Country Status (10)

Country Link
EP (1) EP0257602A1 (ko)
JP (1) JPS6360991A (ko)
KR (1) KR880002879A (ko)
AU (1) AU598018B2 (ko)
DK (1) DK440187A (ko)
IL (1) IL83628A0 (ko)
MY (1) MY101822A (ko)
NZ (1) NZ221549A (ko)
PH (1) PH24872A (ko)
ZA (1) ZA876276B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013729A (en) * 1987-05-11 1991-05-07 Pfizer Inc. Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
EP1193253B1 (en) 1999-05-14 2008-06-25 Kaneka Corporation Process for producing optically active azetidine-2-carboxylic acids
PL2121578T3 (pl) 2007-01-12 2017-02-28 Novartis Ag Sposób wytwarzania kwasu 5-bifenyl-4-amino-2-metylo-pentanowego

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0110280B1 (en) * 1982-11-29 1994-10-12 Schering Corporation Process for the production of penem compounds
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
US4806637A (en) * 1986-03-17 1989-02-21 Schering Corporation 6-(Hydroxyethyl)-2-(heterocyclylthio)-penem-3-carboxylates

Also Published As

Publication number Publication date
MY101822A (en) 1992-01-31
AU7736287A (en) 1988-02-25
PH24872A (en) 1990-12-26
IL83628A0 (en) 1988-01-31
AU598018B2 (en) 1990-06-14
KR880002879A (ko) 1988-05-12
NZ221549A (en) 1989-02-24
DK440187D0 (da) 1987-08-24
JPS6360991A (ja) 1988-03-17
DK440187A (da) 1988-02-26
EP0257602A1 (en) 1988-03-02

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