ZA876072B - Protein protease inhibitors from streptomyces - Google Patents

Protein protease inhibitors from streptomyces

Info

Publication number
ZA876072B
ZA876072B ZA876072A ZA876072A ZA876072B ZA 876072 B ZA876072 B ZA 876072B ZA 876072 A ZA876072 A ZA 876072A ZA 876072 A ZA876072 A ZA 876072A ZA 876072 B ZA876072 B ZA 876072B
Authority
ZA
South Africa
Prior art keywords
streptomyces
protease inhibitors
protein protease
protein
lep
Prior art date
Application number
ZA876072A
Other languages
English (en)
Inventor
Thomas Rodney Berka
Rodney Berka Thomas
James Allan Fornwald
Allan Fornwald James
Joselina Gatmaitan Gorniak
Gatmaitan Gorniak Joselina
Martin Rosenberg
Rosenberg Martin
James Edward Strickler
Edward Strickler James
Dean Perron Taylor
Perron Taylor Dean
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA876072B publication Critical patent/ZA876072B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA876072A 1986-08-18 1987-08-17 Protein protease inhibitors from streptomyces ZA876072B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89724586A 1986-08-18 1986-08-18

Publications (1)

Publication Number Publication Date
ZA876072B true ZA876072B (en) 1988-07-27

Family

ID=25407609

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876072A ZA876072B (en) 1986-08-18 1987-08-17 Protein protease inhibitors from streptomyces

Country Status (9)

Country Link
EP (3) EP0323959A4 (xx)
AT (1) ATE119572T1 (xx)
AU (1) AU606888B2 (xx)
DE (1) DE3751131T2 (xx)
DK (1) DK205188D0 (xx)
IE (1) IE950766L (xx)
PT (1) PT85546B (xx)
WO (1) WO1988001278A1 (xx)
ZA (1) ZA876072B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0538371A4 (en) * 1990-07-11 1993-08-04 Smithkline Beecham Corporation Streptomyces vectors for production of heterologous proteins
US5223418A (en) * 1990-09-28 1993-06-29 Smithkline Beecham Corporation Method of improving the yield of heterologous proteins produced by streptomyces lividans
WO1997011187A1 (en) * 1995-09-22 1997-03-27 Innogenetics N.V. Subtilisin inhibitor of streptomyces venezuelae, and use of the gene sequences for expression and/or secretion of heterologous proteins in streptomyces
KR101879852B1 (ko) * 2017-04-28 2018-07-19 주식회사 만방바이오 신규 스트렙토마이세스속 균주 및 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5434837B2 (xx) * 1972-02-08 1979-10-29
US4717666A (en) * 1984-03-05 1988-01-05 Smithkline Beckman Corporation Cloned streptomycete lividans excretable β-galactosidase gene
EP0108303B1 (en) * 1982-11-01 1987-02-04 Miles Laboratories, Inc. Method for detection and isolation of a microorganism

Also Published As

Publication number Publication date
EP0264175A1 (en) 1988-04-20
DE3751131T2 (de) 1995-07-06
DK205188A (da) 1988-04-14
EP0323959A4 (en) 1990-01-24
PT85546B (pt) 1990-05-31
EP0323959A1 (en) 1989-07-19
AU7879487A (en) 1988-03-08
AU606888B2 (en) 1991-02-21
EP0628632A1 (en) 1994-12-14
WO1988001278A1 (en) 1988-02-25
DE3751131D1 (de) 1995-04-13
DK205188D0 (da) 1988-04-14
IE950766L (en) 1988-02-18
EP0264175B1 (en) 1995-03-08
ATE119572T1 (de) 1995-03-15
PT85546A (en) 1987-09-01

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