ZA869438B - Synthesis of nizatidine - Google Patents

Synthesis of nizatidine

Info

Publication number
ZA869438B
ZA869438B ZA869438A ZA869438A ZA869438B ZA 869438 B ZA869438 B ZA 869438B ZA 869438 A ZA869438 A ZA 869438A ZA 869438 A ZA869438 A ZA 869438A ZA 869438 B ZA869438 B ZA 869438B
Authority
ZA
South Africa
Prior art keywords
nizatidine
synthesis
Prior art date
Application number
ZA869438A
Other languages
English (en)
Inventor
Billy Grinnell Jackson
Bruce Andrew Slomski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA869438B publication Critical patent/ZA869438B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA869438A 1985-12-18 1986-12-15 Synthesis of nizatidine ZA869438B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81013685A 1985-12-18 1985-12-18

Publications (1)

Publication Number Publication Date
ZA869438B true ZA869438B (en) 1988-07-27

Family

ID=25203102

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA869438A ZA869438B (en) 1985-12-18 1986-12-15 Synthesis of nizatidine

Country Status (14)

Country Link
EP (1) EP0230127A1 (de)
JP (1) JPS62155268A (de)
KR (1) KR890002427B1 (de)
CN (1) CN86108424A (de)
AU (1) AU582932B2 (de)
CA (1) CA1277325C (de)
DK (1) DK605386A (de)
FI (1) FI865117A (de)
HU (1) HU196385B (de)
IL (1) IL80961A0 (de)
NZ (1) NZ218647A (de)
PH (1) PH21924A (de)
PT (1) PT83938B (de)
ZA (1) ZA869438B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2038922B1 (es) * 1991-12-30 1994-04-16 Fermentaciones Y Sintesis Espa Procedimiento para la obtencion de nizatidina.
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition
KR100980612B1 (ko) * 2008-09-02 2010-09-07 한국항공우주연구원 유량조절밸브
CN101462969B (zh) * 2009-01-09 2012-04-25 福建深纳生物工程有限公司 1-甲氨基-1-甲氧基-2-硝基乙烯的合成方法
CN102329282A (zh) * 2011-07-15 2012-01-25 海南灵康制药有限公司 一种尼扎替丁化合物及其制法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4474794A (en) * 1982-03-19 1984-10-02 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds
FI840474A (fi) * 1983-02-07 1984-08-08 Lilly Co Eli Foerbaettringar vid syntes av nizatidin samt foerbaettringar beroerande denna.

Also Published As

Publication number Publication date
FI865117A0 (fi) 1986-12-16
EP0230127A1 (de) 1987-07-29
HUT45033A (en) 1988-05-30
NZ218647A (en) 1989-02-24
IL80961A0 (en) 1987-03-31
FI865117A (fi) 1987-06-19
DK605386D0 (da) 1986-12-16
JPS62155268A (ja) 1987-07-10
PT83938B (pt) 1989-06-30
AU6660386A (en) 1987-06-25
AU582932B2 (en) 1989-04-13
PT83938A (en) 1987-01-01
CN86108424A (zh) 1987-08-05
DK605386A (da) 1987-06-19
KR870006024A (ko) 1987-07-08
HU196385B (en) 1988-11-28
CA1277325C (en) 1990-12-04
KR890002427B1 (ko) 1989-07-03
PH21924A (en) 1988-04-08

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