ZA869014B - Benzoic acid and benzoic acid derivatives having anti-inflammatory and analgesic activity - Google Patents
Benzoic acid and benzoic acid derivatives having anti-inflammatory and analgesic activityInfo
- Publication number
- ZA869014B ZA869014B ZA869014A ZA869014A ZA869014B ZA 869014 B ZA869014 B ZA 869014B ZA 869014 A ZA869014 A ZA 869014A ZA 869014 A ZA869014 A ZA 869014A ZA 869014 B ZA869014 B ZA 869014B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzoic acid
- inflammatory
- analgesic activity
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/811,567 US4689182A (en) | 1985-12-20 | 1985-12-20 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA869014B true ZA869014B (en) | 1988-07-27 |
Family
ID=25206907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA869014A ZA869014B (en) | 1985-12-20 | 1986-11-28 | Benzoic acid and benzoic acid derivatives having anti-inflammatory and analgesic activity |
Country Status (14)
Country | Link |
---|---|
US (1) | US4689182A (fr) |
EP (1) | EP0226223A3 (fr) |
JP (1) | JPS62155246A (fr) |
KR (1) | KR900006749B1 (fr) |
CN (1) | CN86108626A (fr) |
AU (1) | AU605123B2 (fr) |
CA (1) | CA1277326C (fr) |
DK (1) | DK604886A (fr) |
FI (1) | FI865108A (fr) |
NO (1) | NO865204L (fr) |
NZ (1) | NZ218588A (fr) |
PH (1) | PH23355A (fr) |
PT (1) | PT83974B (fr) |
ZA (1) | ZA869014B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4980095A (en) * | 1985-12-20 | 1990-12-25 | Warner-Lambert Company | Sodium salt of N-C4-carboxybenzyl nonanamide |
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
WO1989004297A1 (fr) * | 1986-08-19 | 1989-05-18 | Warner-Lambert Company | Derives de 4'-hydroxybenzylamine ayant une activite anti-inflammatoire et analgesique |
US4980366A (en) * | 1986-08-19 | 1990-12-25 | Warner-Lambert Co. | Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity |
AU613598B2 (en) * | 1986-12-26 | 1991-08-08 | Teijin Limited | Aromatic derivative and preparation method thereof |
US5354867A (en) * | 1988-12-06 | 1994-10-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
US5403868A (en) * | 1988-12-23 | 1995-04-04 | Sandoz Ltd. | Capsaicin derivatives |
WO1991000281A2 (fr) * | 1989-06-30 | 1991-01-10 | E.I. Du Pont De Nemours And Company | Imidazoles a substitution aryle a anneau fusionne |
US6344213B1 (en) | 1996-03-29 | 2002-02-05 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5643957A (en) * | 1993-04-22 | 1997-07-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US6461643B2 (en) | 1993-04-22 | 2002-10-08 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
US20010003001A1 (en) | 1993-04-22 | 2001-06-07 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US6001347A (en) | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
EP0886471A4 (fr) | 1996-11-18 | 2002-07-17 | Emisphere Tech Inc | Procede et composition pour induire une tolerance orale chez les mammiferes |
US6358504B1 (en) | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
WO2000006534A1 (fr) | 1998-07-27 | 2000-02-10 | Emisphere Technologies, Inc. | Composes permettant de delivrer des agents actifs et compositions a base de ces composes |
US6440929B1 (en) | 1998-07-27 | 2002-08-27 | Emisphere Technologies, Inc. | Pulmonary delivery of active agents |
ATE329897T1 (de) | 1998-08-07 | 2006-07-15 | Emisphere Tech Inc | Verbindungen und zusammensetzungen zur verabreichung aktiven substanzen |
US6991798B1 (en) | 1998-08-07 | 2006-01-31 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
ATE288415T1 (de) | 1999-04-05 | 2005-02-15 | Emisphere Tech Inc | Dinatrium-salze, monohydrate und ethanol-solvate |
US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
ATE387430T1 (de) | 1999-12-16 | 2008-03-15 | Emisphere Tech Inc | Verbindungen und zusammensetzungen zur abgabe aktiver wirkstoffe |
CN103864638B (zh) * | 2012-12-14 | 2015-12-09 | 沈阳药科大学 | 一种苯甲酸类化合物及其制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2281761A1 (fr) * | 1974-08-13 | 1976-03-12 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
DE2517229A1 (de) * | 1975-04-18 | 1976-10-28 | Boehringer Mannheim Gmbh | Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung |
DK148576A (da) * | 1975-04-18 | 1976-10-19 | Boehringer Mannheim Gmbh | Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling |
DE2532420A1 (de) * | 1975-07-19 | 1977-02-03 | Boehringer Mannheim Gmbh | Phenylessigsaeure-derivate und verfahren zu ihrer herstellung |
AU492025B2 (en) * | 1976-01-22 | 1977-07-28 | ITALIANA Sp. A | Derivatives of aminoethylcyclohexane-carboxylic acid |
FR2388789A1 (fr) * | 1977-04-27 | 1978-11-24 | Seuref Ag | Derives d'acide benzoique, leur procede de preparation et leur application therapeutique |
JPS549266A (en) * | 1977-06-21 | 1979-01-24 | Yoshitarou Takatori | Production of 44n*nn maleoyliminomethyl benzoic acid |
DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
US4313958A (en) * | 1980-10-24 | 1982-02-02 | The Procter & Gamble Company | Method of producing analgesia |
US4460602A (en) * | 1981-06-30 | 1984-07-17 | The Procter & Gamble Company | Urea derivatives |
US4401663A (en) * | 1981-06-30 | 1983-08-30 | The Procter & Gamble Company | Novel sulfonamide derivatives |
US4424203A (en) * | 1983-03-04 | 1984-01-03 | Pakhomov Gennady N | Gel for dental caries prevention |
US4544669A (en) * | 1983-07-14 | 1985-10-01 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4544668A (en) * | 1983-07-14 | 1985-10-01 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4532139A (en) * | 1983-07-14 | 1985-07-30 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4493848A (en) * | 1983-07-14 | 1985-01-15 | The Procter & Gamble Company | Compositions and methods useful for producing analgesia |
US4681897A (en) * | 1984-01-16 | 1987-07-21 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
US4599342A (en) * | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
-
1985
- 1985-12-20 US US06/811,567 patent/US4689182A/en not_active Expired - Fee Related
-
1986
- 1986-11-28 ZA ZA869014A patent/ZA869014B/xx unknown
- 1986-12-01 CA CA000524255A patent/CA1277326C/fr not_active Expired - Fee Related
- 1986-12-10 NZ NZ218588A patent/NZ218588A/xx unknown
- 1986-12-15 FI FI865108A patent/FI865108A/fi not_active Application Discontinuation
- 1986-12-16 DK DK604886A patent/DK604886A/da not_active Application Discontinuation
- 1986-12-19 CN CN198686108626A patent/CN86108626A/zh active Pending
- 1986-12-19 PT PT83974A patent/PT83974B/pt not_active IP Right Cessation
- 1986-12-19 EP EP86117748A patent/EP0226223A3/fr not_active Withdrawn
- 1986-12-19 AU AU66813/86A patent/AU605123B2/en not_active Expired - Fee Related
- 1986-12-19 JP JP61301914A patent/JPS62155246A/ja active Pending
- 1986-12-19 PH PH34621A patent/PH23355A/en unknown
- 1986-12-19 NO NO865204A patent/NO865204L/no unknown
- 1986-12-20 KR KR1019860010989A patent/KR900006749B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4689182A (en) | 1987-08-25 |
CA1277326C (fr) | 1990-12-04 |
CN86108626A (zh) | 1987-07-22 |
FI865108A (fi) | 1987-06-21 |
EP0226223A2 (fr) | 1987-06-24 |
DK604886D0 (da) | 1986-12-16 |
EP0226223A3 (fr) | 1990-01-03 |
NO865204L (no) | 1987-06-22 |
AU6681386A (en) | 1987-06-25 |
NZ218588A (en) | 1990-03-27 |
JPS62155246A (ja) | 1987-07-10 |
KR870005973A (ko) | 1987-07-08 |
AU605123B2 (en) | 1991-01-10 |
KR900006749B1 (ko) | 1990-09-20 |
DK604886A (da) | 1987-06-21 |
NO865204D0 (no) | 1986-12-19 |
PT83974A (en) | 1987-01-01 |
PT83974B (pt) | 1989-05-12 |
FI865108A0 (fi) | 1986-12-15 |
PH23355A (en) | 1989-07-14 |
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