ZA865536B - Purification procedure of tpa from crude preparations - Google Patents

Purification procedure of tpa from crude preparations

Info

Publication number
ZA865536B
ZA865536B ZA865536A ZA865536A ZA865536B ZA 865536 B ZA865536 B ZA 865536B ZA 865536 A ZA865536 A ZA 865536A ZA 865536 A ZA865536 A ZA 865536A ZA 865536 B ZA865536 B ZA 865536B
Authority
ZA
South Africa
Prior art keywords
tpa
purification procedure
crude preparations
preparations
crude
Prior art date
Application number
ZA865536A
Other languages
English (en)
Inventor
Mitsuyoshi Morii
Masaharu Ohoka
Nobuhiro Kawashimi
Noriko Morii
Toshihiko Suzuki
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of ZA865536B publication Critical patent/ZA865536B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
ZA865536A 1985-08-01 1986-07-24 Purification procedure of tpa from crude preparations ZA865536B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60168601A JPS6229975A (ja) 1985-08-01 1985-08-01 粗ｔＰＡの精製法

Publications (1)

Publication Number Publication Date
ZA865536B true ZA865536B (en) 1987-03-25

Family

ID=15871078

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865536A ZA865536B (en) 1985-08-01 1986-07-24 Purification procedure of tpa from crude preparations

Country Status (9)

Country Link
US (1) US5110736A (fr)
EP (1) EP0210870B1 (fr)
JP (1) JPS6229975A (fr)
CA (1) CA1314833C (fr)
DE (1) DE3681528D1 (fr)
DK (1) DK369686A (fr)
FI (1) FI87793C (fr)
NO (1) NO172396C (fr)
ZA (1) ZA865536B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE107664T1 (de) * 1985-10-04 1994-07-15 South African Inventions Reagens und verfahren.
JPS6463378A (en) * 1986-08-11 1989-03-09 Mitsui Toatsu Chemicals Separation of single stranded tpa and double standard tpa
HUT51901A (en) * 1987-06-22 1990-06-28 Genetics Inst Process for production of new trombolitic ensimes
US5411864A (en) * 1987-11-05 1995-05-02 Genentech, Inc. Method of purifying recombinant proteins from corresponding host cell proteins
DE3832898A1 (de) * 1988-09-28 1990-04-12 Boehringer Mannheim Gmbh Praeparat von in prokaryonten exprimiertem plasminogenaktivator
WO2001038560A2 (fr) * 1999-11-22 2001-05-31 American Red Cross Nouvelle methode permettant de detecter la presence d'une forme d'enzyme fonctionnellement active dans des echantillons biologiques et kit
US7200993B2 (en) * 2005-03-31 2007-04-10 Caterpillar Inc Electro-hydraulic steering control system
CN114426962B (zh) * 2021-12-21 2024-06-18 佛山汉腾生物科技有限公司 t-PA纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112122B1 (fr) * 1982-12-14 1991-08-28 South African Inventions Development Corporation Activateur de plasminogène
PH22337A (en) * 1983-11-21 1988-08-12 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast

Also Published As

Publication number Publication date
DK369686A (da) 1987-02-02
NO172396B (no) 1993-04-05
CA1314833C (fr) 1993-03-23
FI863111A0 (fi) 1986-07-30
US5110736A (en) 1992-05-05
NO863095D0 (no) 1986-07-31
EP0210870A3 (en) 1988-01-07
DK369686D0 (da) 1986-08-01
FI863111A (fi) 1987-02-02
FI87793B (fi) 1992-11-13
EP0210870B1 (fr) 1991-09-18
FI87793C (fi) 1993-02-25
NO863095L (no) 1987-02-02
EP0210870A2 (fr) 1987-02-04
JPS6229975A (ja) 1987-02-07
DE3681528D1 (de) 1991-10-24
NO172396C (no) 1993-07-14

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