ZA865462B - Tetrahydroisoquinoline derivatives as beta-adrenergic receptor antagonists - Google Patents
Tetrahydroisoquinoline derivatives as beta-adrenergic receptor antagonistsInfo
- Publication number
- ZA865462B ZA865462B ZA865462A ZA865462A ZA865462B ZA 865462 B ZA865462 B ZA 865462B ZA 865462 A ZA865462 A ZA 865462A ZA 865462 A ZA865462 A ZA 865462A ZA 865462 B ZA865462 B ZA 865462B
- Authority
- ZA
- South Africa
- Prior art keywords
- beta
- receptor antagonists
- adrenergic receptor
- tetrahydroisoquinoline derivatives
- tetrahydroisoquinoline
- Prior art date
Links
- 239000000674 adrenergic antagonist Substances 0.000 title 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 title 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 title 1
- 125000003039 tetrahydroisoquinolinyl group Chemical class C1(NCCC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858518634A GB8518634D0 (en) | 1985-07-23 | 1985-07-23 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA865462B true ZA865462B (en) | 1987-04-29 |
Family
ID=10582746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA865462A ZA865462B (en) | 1985-07-23 | 1986-07-22 | Tetrahydroisoquinoline derivatives as beta-adrenergic receptor antagonists |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US4707485A (da) |
| EP (1) | EP0210827A3 (da) |
| JP (1) | JPS6222768A (da) |
| AU (1) | AU585039B2 (da) |
| DK (1) | DK346186A (da) |
| ES (1) | ES2000714A6 (da) |
| GB (1) | GB8518634D0 (da) |
| GR (1) | GR861899B (da) |
| PT (1) | PT83025B (da) |
| ZA (1) | ZA865462B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5332821A (en) * | 1987-03-20 | 1994-07-26 | Hoffmann-La Roche Inc. | Process for preparing isoquinolines |
| BE1002413A3 (nl) * | 1988-05-11 | 1991-01-29 | Spoelders Ludy | Inrichting voor het in zaagtandvorm tussen twee paren van boven- en ondermessen uitsnijden en verlijmen van de einden van fineerbanden. |
| WO1999016752A1 (en) * | 1997-09-30 | 1999-04-08 | Molecular Designs International, Inc. | β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING |
| US6593341B2 (en) | 2001-03-29 | 2003-07-15 | Molecular Design International, Inc. | β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same |
| US6596734B1 (en) | 2002-10-11 | 2003-07-22 | Molecular Design International, Inc. | Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists |
| ATE554769T1 (de) * | 2006-12-06 | 2012-05-15 | Cornell Res Foundation Inc | Neuromuskuläre blocker mit mittlerer dauer und antagonisten advon |
| WO2010107488A1 (en) | 2009-03-17 | 2010-09-23 | Cornell University | Reversible nondepolarizing neuromuscular blockade agents and methods for their use |
| WO2011022491A1 (en) | 2009-08-19 | 2011-02-24 | Cornell University | Cysteine for physiological injection |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1250828B (de) * | 1962-10-10 | 1967-09-28 | Chinoin Gyogyszer es Vegyeszeti Termekek Gyära R.T., Budapest | Verfahren zur Herstellung des spasmolytisch wirksamen 6,7,3',4' - Tetraäthoxy -l-benzyliden-1,2,3,4tetrahydroisochinolins und seiner Salze |
| SE352889B (da) * | 1968-01-31 | 1973-01-15 | Tanabe Seiyaku Co | |
| US3910915A (en) * | 1973-07-23 | 1975-10-07 | Searle & Co | 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines |
| US3905982A (en) * | 1973-07-23 | 1975-09-16 | Searle & Co | 1-Aryl-n-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related compounds |
| US4514569A (en) * | 1982-01-28 | 1985-04-30 | Hendrickson James B | Synthesis of 1-substituted isoquinolines |
-
1985
- 1985-07-23 GB GB858518634A patent/GB8518634D0/en active Pending
-
1986
- 1986-06-24 US US06/877,932 patent/US4707485A/en not_active Expired - Fee Related
- 1986-07-16 AU AU60247/86A patent/AU585039B2/en not_active Ceased
- 1986-07-21 GR GR861899A patent/GR861899B/el unknown
- 1986-07-21 PT PT83025A patent/PT83025B/pt not_active IP Right Cessation
- 1986-07-21 DK DK346186A patent/DK346186A/da not_active Application Discontinuation
- 1986-07-22 EP EP86305636A patent/EP0210827A3/en not_active Withdrawn
- 1986-07-22 ZA ZA865462A patent/ZA865462B/xx unknown
- 1986-07-22 ES ES8600468A patent/ES2000714A6/es not_active Expired
- 1986-07-22 JP JP61173542A patent/JPS6222768A/ja active Pending
-
1987
- 1987-08-24 US US07/088,624 patent/US4767862A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT83025B (en) | 1988-07-08 |
| JPS6222768A (ja) | 1987-01-30 |
| EP0210827A2 (en) | 1987-02-04 |
| US4707485A (en) | 1987-11-17 |
| DK346186D0 (da) | 1986-07-21 |
| EP0210827A3 (en) | 1988-03-16 |
| GB8518634D0 (en) | 1985-08-29 |
| PT83025A (en) | 1986-08-01 |
| DK346186A (da) | 1987-01-24 |
| AU585039B2 (en) | 1989-06-08 |
| ES2000714A6 (es) | 1988-03-16 |
| GR861899B (en) | 1986-11-24 |
| US4767862A (en) | 1988-08-30 |
| AU6024786A (en) | 1987-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG39393G (en) | Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity | |
| GB8600783D0 (en) | N-methyl-d-aspartate receptor antagonists | |
| GB2135311B (en) | Novel xanthine-type adenosine receptor antagonists | |
| GB2175898B (en) | Morphinan derivatives | |
| GB8507526D0 (en) | Isoquinoline derivatives | |
| PH22655A (en) | Gnrh antagonists iv | |
| GB2192001B (en) | Melatonin antagonist | |
| ZA865462B (en) | Tetrahydroisoquinoline derivatives as beta-adrenergic receptor antagonists | |
| ZA858892B (en) | Basic v1-vasopressin antagonists | |
| ZA851682B (en) | Des-proline vasopressin antagonists | |
| ZA869059B (en) | Novel tetrahydroisoquinoline derivatives | |
| EP0161102A3 (en) | Isoquinoline derivatives | |
| ZA858891B (en) | V1-vasopressin antagonists | |
| ZA86333B (en) | Thromboxane antagonists | |
| EG17738A (en) | Vasobrisin antagonists | |
| EP0207500A3 (en) | Isoquinoline derivatives | |
| GR80712B (en) | Dihydroisoquinoline derivatives | |
| ZA894097B (en) | Alpha-adrenergic receptor antagonists | |
| ZA865461B (en) | Tetrahydroisoquinoline derivatives as beta-adrenergic receptor antagonists | |
| ZA864015B (en) | Isoquinoline derivatives | |
| ZW3585A1 (en) | Des-proline vasopressin antagonists | |
| PT83760A (en) | Vasopressin antagonists | |
| ZA883601B (en) | Vaspressin antagonists | |
| IE852793L (en) | Chiral b-adrenoceptor antagonists | |
| IE873198L (en) | Ó-adreno receptor antagonists |