ZA865328B - Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals - Google Patents

Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals

Info

Publication number
ZA865328B
ZA865328B ZA865328A ZA865328A ZA865328B ZA 865328 B ZA865328 B ZA 865328B ZA 865328 A ZA865328 A ZA 865328A ZA 865328 A ZA865328 A ZA 865328A ZA 865328 B ZA865328 B ZA 865328B
Authority
ZA
South Africa
Prior art keywords
thia
oxa
pharmaceuticals
preparation
azabicycloalkane derivatives
Prior art date
Application number
ZA865328A
Other languages
English (en)
Inventor
Francis David King
Michael Stewart Hadley
Roger Thomas Martin
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA865328B publication Critical patent/ZA865328B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA865328A 1985-07-19 1986-07-17 Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals ZA865328B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858518236A GB8518236D0 (en) 1985-07-19 1985-07-19 Compounds

Publications (1)

Publication Number Publication Date
ZA865328B true ZA865328B (en) 1987-06-24

Family

ID=10582523

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865328A ZA865328B (en) 1985-07-19 1986-07-17 Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals

Country Status (12)

Country Link
US (2) US4826839A (xx)
EP (1) EP0226267B1 (xx)
JP (1) JPS6230785A (xx)
AU (1) AU594351B2 (xx)
DE (1) DE3687515T2 (xx)
DK (1) DK340886A (xx)
ES (1) ES2000524A6 (xx)
GB (1) GB8518236D0 (xx)
GR (1) GR861874B (xx)
NZ (1) NZ216880A (xx)
PT (1) PT83016A (xx)
ZA (1) ZA865328B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
US4895943A (en) * 1988-10-25 1990-01-23 Pfizer Inc. Preparation of 1,4-diazabicyclo(3.2.2)nonane
US5185333A (en) * 1989-07-03 1993-02-09 Yoshitomi Pharmaceutical Industries, Ltd. Benzazine compounds and pharmaceutical uses thereof
GB9027098D0 (en) * 1990-12-13 1991-02-06 Beecham Group Plc Pharmaceuticals
WO1993008191A1 (en) * 1991-10-15 1993-04-29 Warner-Lambert Company Azabicyclo oxime and amine cholinergic agents and methods of treatment
US5244907A (en) * 1992-03-26 1993-09-14 A. H. Robins Company, Incorporated Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5190953A (en) * 1992-03-26 1993-03-02 A. H. Robins Company, Incorporated Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5679673A (en) * 1992-09-24 1997-10-21 The United States Of America, Represented By The Department Of Health And Human Services Aralkyl bridged diazabicycloalkane derivatives for CNS disorders
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
FR2827288B1 (fr) * 2001-07-12 2003-10-31 Servier Lab Nouveaux derives d'octahydro-2h-pyrido[1,2-a]pyrazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
IL61972A0 (en) * 1980-01-30 1981-02-27 Beecham Group Ltd Azabicyclic compounds,their preparation and pharmaceutical compositions containing them
US4352802A (en) * 1980-06-10 1982-10-05 Beecham Group Limited Bicyclo[3.3.1]nonyl-benzamide
AU563225B2 (en) * 1982-04-14 1987-07-02 Alizyme Therapeutics Limited I-aza bicyclic compounds
US4612319A (en) * 1982-04-14 1986-09-16 Beecham Group P.L.C. Bridged quinolizidinylbenzamides, compositions containing them and methods for their use

Also Published As

Publication number Publication date
GB8518236D0 (en) 1985-08-29
DK340886A (da) 1987-01-20
EP0226267A1 (en) 1987-06-24
DK340886D0 (da) 1986-07-17
NZ216880A (en) 1989-09-27
AU6027486A (en) 1987-01-22
PT83016A (en) 1986-08-01
GR861874B (en) 1986-11-10
US4883874A (en) 1989-11-28
EP0226267B1 (en) 1993-01-13
AU594351B2 (en) 1990-03-08
DE3687515T2 (de) 1993-05-13
DE3687515D1 (de) 1993-02-25
JPS6230785A (ja) 1987-02-09
ES2000524A6 (es) 1988-03-01
US4826839A (en) 1989-05-02

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