ZA864199B - Steroido [3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof - Google Patents

Steroido [3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof

Info

Publication number
ZA864199B
ZA864199B ZA864199A ZA864199A ZA864199B ZA 864199 B ZA864199 B ZA 864199B ZA 864199 A ZA864199 A ZA 864199A ZA 864199 A ZA864199 A ZA 864199A ZA 864199 B ZA864199 B ZA 864199B
Authority
ZA
South Africa
Prior art keywords
steroido
preparation
antiandrogenic agents
pyrazoles useful
pyrazoles
Prior art date
Application number
ZA864199A
Other languages
English (en)
Inventor
Robert George Christiansen
Malcolm Rice Bell
John Lawrence Herrmann
Chester Joseph Opalka
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ZA864199B publication Critical patent/ZA864199B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
ZA864199A 1985-06-24 1986-06-05 Steroido [3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof ZA864199B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74837885A 1985-06-24 1985-06-24
US06/849,582 US4684636A (en) 1985-06-24 1986-04-08 Antiandrogenic sulfonylsteroidopyrazoles and processes for preparation method of use and compositions thereof

Publications (1)

Publication Number Publication Date
ZA864199B true ZA864199B (en) 1987-01-28

Family

ID=27114932

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA864199A ZA864199B (en) 1985-06-24 1986-06-05 Steroido [3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof

Country Status (19)

Country Link
US (1) US4684636A (pt)
EP (1) EP0207375B1 (pt)
KR (1) KR910002228B1 (pt)
AR (2) AR242798A1 (pt)
AT (1) ATE45164T1 (pt)
AU (1) AU581767B2 (pt)
CA (1) CA1255294A (pt)
DE (1) DE3664775D1 (pt)
DK (1) DK293786A (pt)
ES (2) ES8800690A1 (pt)
FI (1) FI83425C (pt)
GR (1) GR861613B (pt)
IL (1) IL79046A0 (pt)
MY (1) MY101921A (pt)
NO (1) NO166039C (pt)
NZ (1) NZ216438A (pt)
PH (1) PH22087A (pt)
PT (1) PT82837B (pt)
ZA (1) ZA864199B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100882A (en) * 1990-06-21 1992-03-31 Sterling Drug Inc. Antiandrogenic sulfonylsteroidofurans
US5134135A (en) * 1990-06-21 1992-07-28 Sterling Drug Inc. Antiandrogenic sulfonylsteroidooxazoles
US5053405A (en) * 1990-06-21 1991-10-01 Sterling Drug Inc. Antiandrogenic sulfonylsteroidothiazoles
DE4021433A1 (de) * 1990-07-04 1992-01-09 Schering Ag Antiandrogene mit steroid(3,2-c)pyrazol-struktur
US5223268A (en) * 1991-05-16 1993-06-29 Sterling Drug, Inc. Low solubility drug-coated bead compositions
US5175155A (en) * 1991-10-07 1992-12-29 Sterling Winthrop Inc. Win 49596-finasteride method of use and compositions
DE4227465A1 (de) * 1992-08-17 1994-02-24 Schering Ag Antiandrogene Steroide mit aneliertem Fünfring
EP1364643A4 (en) * 2000-12-01 2009-07-15 Kyowa Hakko Kogyo Kk COMPOSITION WITH IMPROVED ORAL SOLUBILITY OR ABSORBABILITY

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL100550C (pt) * 1959-02-16
US2945852A (en) * 1959-05-20 1960-07-19 Searle & Co 17-oxygenated 9alpha-substituted androstano [3, 2-c] pyrazoles and derivatives
US4297350A (en) * 1978-10-10 1981-10-27 The Upjohn Company Male contraceptive steroids and methods of use
US4356175A (en) * 1978-10-10 1982-10-26 The Upjohn Company 17β-Hydroxy-17α-methyl-5α-androstano-[3,2-c]pyrazole 17-methyl ether

Also Published As

Publication number Publication date
ES556422A0 (es) 1987-11-16
ATE45164T1 (de) 1989-08-15
PH22087A (en) 1988-05-20
MY101921A (en) 1992-02-15
PT82837A (en) 1986-07-01
FI83425C (fi) 1991-07-10
KR910002228B1 (ko) 1991-04-08
ES8801929A1 (es) 1988-03-01
AR242798A1 (es) 1993-05-31
CA1255294A (en) 1989-06-06
FI862637A0 (fi) 1986-06-19
NO166039C (no) 1991-05-29
US4684636A (en) 1987-08-04
FI862637A (fi) 1986-12-25
KR870010074A (ko) 1987-11-30
ES557699A0 (es) 1988-03-01
EP0207375B1 (en) 1989-08-02
GR861613B (en) 1986-10-30
AU581767B2 (en) 1989-03-02
NO166039B (no) 1991-02-11
DK293786A (da) 1986-12-25
PT82837B (pt) 1988-04-21
NZ216438A (en) 1989-01-06
DK293786D0 (da) 1986-06-23
DE3664775D1 (en) 1989-09-07
NO862506D0 (no) 1986-06-23
FI83425B (fi) 1991-03-28
ES8800690A1 (es) 1987-11-16
NO862506L (no) 1986-12-29
AR243201A1 (es) 1993-07-30
AU5896586A (en) 1987-01-08
EP0207375A1 (en) 1987-01-07
IL79046A0 (en) 1986-09-30

Similar Documents

Publication Publication Date Title
PH23081A (en) Avermectin derivatives and the use thereof as antiparasitic agents
IL83034A (en) Alpha-aryl-alpha-phenylethyl-1h-1,2,4-triazole-1-propanenitriles,their preparation and their use as fungicides
IL82687A0 (en) 1,2,3,6-tetrahydro-5-nitro-pyrimidine derivatives,their preparation and their use as pesticides
IL95946A0 (en) Preparation of tetrabromo-4,4'-alkylidenediphenols
NZ219606A (en) 1,1-disubstituted-cyclopropane derivatives and fungicidal compositions
IL95172A0 (en) Topical spironolactone composition
ZA864199B (en) Steroido [3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof
AU6292286A (en) N-substituted-3,4,5,6,-tetrahydrophthalimides, their preparation and use
PH24914A (en) 1h-pyrazole-1-alkanamides and preparation useful as antiarrhythmic agents
ZA932576B (en) 1,2,4-benzothiadiazine-3-carboxylic acid derivatives, their preparation and their use
IL74181A0 (en) 1,3,2-dioxaborinanes,their preparation and their use as biocides
IL75366A0 (en) Substituted phenylsulphonylureas,their preparation and their use as plant-treatment agents
AU621997B2 (en) Azole-1-alkanamides as antiarrhythmic agents and preparation thereof
EP0238357A3 (en) 1,2,4-triazinone derivatives, their preparation and use
IL80703A0 (en) Substituted 1,2,4-triazole derivatives,their preparation and their use as pesticides
NZ216769A (en) 1,2,4-triazole derivatives and pesticidal compositions
AR242578A1 (es) Procedimiento para preparar un grupo de tetrahidro ciclohepta 1,2-c:4,3-c' dipirazoles y benzo 1,2-c:4,3-c' dipirazoles metilados.
AU5006490A (en) Azole-1-alkanamides as antiarrhythmic agents and preparation thereof
NZ219645A (en) Pyrazoles and gametocidal compositions
AU620223B2 (en) Azole-1-alkanamides as antiarrhythmic agents and preparation thereof
ZA859689B (en) Triazolo-(3,2-c)perhydroxazin-8-one derivatives
AU5006690A (en) Azole-l-alkanamides as antiarrhythmic agents and preparation thereof
IL95492A0 (en) Preparation of 3,7-dialkylxanthines
AU5051190A (en) Azole-l-alkanamides as antiarrhythmic agents and preparation thereof
IL76391A0 (en) Substituted 1,1-bis-azolyl-butan-2-ones and-ols,their preparation and their use as fungicides