ZA862744B - Anticonvulsant dioxolane methane sulfamates - Google Patents

Anticonvulsant dioxolane methane sulfamates

Info

Publication number
ZA862744B
ZA862744B ZA862744A ZA862744A ZA862744B ZA 862744 B ZA862744 B ZA 862744B ZA 862744 A ZA862744 A ZA 862744A ZA 862744 A ZA862744 A ZA 862744A ZA 862744 B ZA862744 B ZA 862744B
Authority
ZA
South Africa
Prior art keywords
sulfamates
anticonvulsant
dioxolane
methane
methane sulfamates
Prior art date
Application number
ZA862744A
Other languages
English (en)
Inventor
Bruce Eliot Maryanoff
Samuel Othniel Nortey
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of ZA862744B publication Critical patent/ZA862744B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ZA862744A 1985-04-12 1986-04-11 Anticonvulsant dioxolane methane sulfamates ZA862744B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/722,869 US4591601A (en) 1985-04-12 1985-04-12 Anticonvulsant dioxolane methane sulfamates

Publications (1)

Publication Number Publication Date
ZA862744B true ZA862744B (en) 1987-11-25

Family

ID=24903753

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA862744A ZA862744B (en) 1985-04-12 1986-04-11 Anticonvulsant dioxolane methane sulfamates

Country Status (9)

Country Link
US (1) US4591601A (fr)
EP (1) EP0198686A3 (fr)
JP (1) JPS61263973A (fr)
AU (1) AU579463B2 (fr)
CA (1) CA1252109A (fr)
DK (1) DK167586A (fr)
ES (1) ES8801242A1 (fr)
GR (1) GR860953B (fr)
ZA (1) ZA862744B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792569A (en) * 1987-08-27 1988-12-20 Mcneilab, Inc. Anticonvulsant phenethyl sulfamates
US5194446A (en) * 1989-06-12 1993-03-16 A. H. Robins Company, Incorporated Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals
US5273993A (en) * 1989-06-12 1993-12-28 A. H. Robins Company, Incorporated Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals
US5192785A (en) * 1989-09-03 1993-03-09 A. H. Robins Company, Incorporated Sulfamates as antiglaucoma agents
US6011024A (en) 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
US6903084B2 (en) 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
IL140861A (en) * 1998-07-15 2004-06-01 Bristol Myers Squibb Co Dioxolane pentanoic acid and processes for the preparation thereof
US7335650B2 (en) * 2000-01-14 2008-02-26 Sterix Limited Composition
US7422775B2 (en) * 2005-05-17 2008-09-09 Applied Materials, Inc. Process for low temperature plasma deposition of an optical absorption layer and high speed optical annealing
US20090318520A1 (en) 2008-06-20 2009-12-24 Afecta Pharmaceuticals Drive Use of isoindoles for the treatment of neurobehavioral disorders
EP2861571B1 (fr) 2012-06-15 2017-05-03 Bio-Pharm Solutions Co., Ltd. Composé de sulfamate de phénylalkyle et composition myorelaxante le contenant
EP3443959A1 (fr) * 2013-12-12 2019-02-20 Bio-Pharm Solutions Co., Ltd. Composés dérivés de sulfamate pour utilisation dans le traitement ou l'atténuation de la douleur
WO2015088272A1 (fr) * 2013-12-12 2015-06-18 Bio-Pharm Solutions Co., Ltd. Composés dérivés de sulfamate destinés à être utilisés pour le traitement ou le soulagement de la douleur
US9937145B2 (en) 2013-12-12 2018-04-10 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compound for use in preventing or treating epilepsy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058981A (en) * 1958-11-14 1962-10-16 Richardson Merrell Inc 2-methyl-2-nonyl-4-hydroxymethyl-1, 3-dioxolane and carbamates thereof
DE1131226B (de) * 1958-12-24 1962-06-14 Riedel De Haeen Ag Verfahren zur Herstellung der Carbaminsaeureester von 4-Oxymethyl-1,3-dioxolanen
BE622353A (fr) * 1961-09-15
US3948953A (en) * 1969-08-05 1976-04-06 Texaco Inc. Dioxolane derivatives having surfactant properties
US3997585A (en) * 1974-12-30 1976-12-14 Ortho Pharmaceutical Corporation Aliphatic sulfamates
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them
JPS57197258A (en) * 1981-05-29 1982-12-03 Taiho Yakuhin Kogyo Kk Sulfonic ester derivative and its preparation

Also Published As

Publication number Publication date
DK167586A (da) 1986-10-13
AU5601086A (en) 1986-10-16
ES553874A0 (es) 1988-01-01
DK167586D0 (da) 1986-04-11
EP0198686A2 (fr) 1986-10-22
EP0198686A3 (fr) 1987-10-21
US4591601A (en) 1986-05-27
CA1252109A (fr) 1989-04-04
ES8801242A1 (es) 1988-01-01
GR860953B (en) 1986-08-06
JPS61263973A (ja) 1986-11-21
AU579463B2 (en) 1988-11-24

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