ZA86173B - Octahydroindolizine compounds useful as analgesics - Google Patents
Octahydroindolizine compounds useful as analgesicsInfo
- Publication number
- ZA86173B ZA86173B ZA86173A ZA86173A ZA86173B ZA 86173 B ZA86173 B ZA 86173B ZA 86173 A ZA86173 A ZA 86173A ZA 86173 A ZA86173 A ZA 86173A ZA 86173 B ZA86173 B ZA 86173B
- Authority
- ZA
- South Africa
- Prior art keywords
- analgesics
- compounds useful
- octahydroindolizine
- octahydroindolizine compounds
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/689,883 US4582836A (en) | 1985-01-09 | 1985-01-09 | Octahydroindolizine compounds useful as analgesics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA86173B true ZA86173B (en) | 1987-08-26 |
Family
ID=24770255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA86173A ZA86173B (en) | 1985-01-09 | 1986-01-09 | Octahydroindolizine compounds useful as analgesics |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4582836A (de) |
| EP (1) | EP0187711B1 (de) |
| JP (1) | JPS61204182A (de) |
| CN (1) | CN86100131A (de) |
| AT (1) | ATE55907T1 (de) |
| CA (1) | CA1255306A (de) |
| DE (1) | DE3673657D1 (de) |
| DK (1) | DK7286A (de) |
| ES (2) | ES8703470A1 (de) |
| FI (1) | FI860074A (de) |
| GR (1) | GR860021B (de) |
| HU (1) | HU195964B (de) |
| NO (1) | NO860048L (de) |
| NZ (1) | NZ214573A (de) |
| PH (1) | PH21295A (de) |
| ZA (1) | ZA86173B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4689329A (en) * | 1986-02-04 | 1987-08-25 | Mcneilab, Inc. | 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates |
| US4683239A (en) * | 1986-04-10 | 1987-07-28 | Mcneilab, Inc. | 3-diphenyl substituted octahydroindolizine analgesic compounds |
| US4716172A (en) * | 1986-04-10 | 1987-12-29 | Mcneilab, Inc. | 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates |
| US4800207A (en) * | 1987-11-02 | 1989-01-24 | Mcneilab, Inc. | Hexahydropyrrolizine compounds useful as analgesics |
| AU653957B2 (en) * | 1990-09-20 | 1994-10-20 | Merrell Dow Pharmaceuticals Inc. | 1-aryl-3-pyridinyl-2-propene-1-ones |
| US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
| AU2012258618B2 (en) | 2011-05-26 | 2017-05-25 | Sunovion Pharmaceuticals Inc. | Metabotropic glutamate receptors 5 modulators and methods of use thereof |
-
1985
- 1985-01-09 US US06/689,883 patent/US4582836A/en not_active Expired - Lifetime
- 1985-12-16 NZ NZ214573A patent/NZ214573A/en unknown
-
1986
- 1986-01-07 GR GR860021A patent/GR860021B/el unknown
- 1986-01-07 CA CA000499150A patent/CA1255306A/en not_active Expired
- 1986-01-07 JP JP61000345A patent/JPS61204182A/ja active Pending
- 1986-01-08 EP EP86300086A patent/EP0187711B1/de not_active Expired - Lifetime
- 1986-01-08 HU HU8680A patent/HU195964B/hu not_active IP Right Cessation
- 1986-01-08 PH PH33265A patent/PH21295A/en unknown
- 1986-01-08 DE DE8686300086T patent/DE3673657D1/de not_active Expired - Fee Related
- 1986-01-08 ES ES550742A patent/ES8703470A1/es not_active Expired
- 1986-01-08 AT AT86300086T patent/ATE55907T1/de not_active IP Right Cessation
- 1986-01-08 DK DK7286A patent/DK7286A/da not_active Application Discontinuation
- 1986-01-08 FI FI860074A patent/FI860074A/fi not_active Application Discontinuation
- 1986-01-08 NO NO860048A patent/NO860048L/no unknown
- 1986-01-09 CN CN198686100131A patent/CN86100131A/zh active Pending
- 1986-01-09 ZA ZA86173A patent/ZA86173B/xx unknown
- 1986-03-20 ES ES553207A patent/ES8707530A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO860048L (no) | 1986-07-10 |
| EP0187711A2 (de) | 1986-07-16 |
| DK7286A (da) | 1986-07-10 |
| NZ214573A (en) | 1988-04-29 |
| JPS61204182A (ja) | 1986-09-10 |
| HU195964B (en) | 1988-08-29 |
| EP0187711A3 (en) | 1987-08-12 |
| FI860074A0 (fi) | 1986-01-08 |
| EP0187711B1 (de) | 1990-08-29 |
| HUT41025A (en) | 1987-03-30 |
| ES8703470A1 (es) | 1987-02-16 |
| PH21295A (en) | 1987-09-28 |
| GR860021B (en) | 1986-05-08 |
| FI860074A (fi) | 1986-07-10 |
| CN86100131A (zh) | 1986-10-15 |
| ES550742A0 (es) | 1987-02-16 |
| ES553207A0 (es) | 1987-08-01 |
| US4582836A (en) | 1986-04-15 |
| CA1255306A (en) | 1989-06-06 |
| DK7286D0 (da) | 1986-01-08 |
| ATE55907T1 (de) | 1990-09-15 |
| DE3673657D1 (de) | 1990-10-04 |
| ES8707530A1 (es) | 1987-08-01 |
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