GR860021B - Octahydro indolizine compounds useful as analgesics - Google Patents

Octahydro indolizine compounds useful as analgesics

Info

Publication number
GR860021B
GR860021B GR860021A GR860100021A GR860021B GR 860021 B GR860021 B GR 860021B GR 860021 A GR860021 A GR 860021A GR 860100021 A GR860100021 A GR 860100021A GR 860021 B GR860021 B GR 860021B
Authority
GR
Greece
Prior art keywords
analgesics
compounds useful
indolizine compounds
octahydro indolizine
octahydro
Prior art date
Application number
GR860021A
Other languages
English (en)
Inventor
Carmosin Joel Richard
Carson Robert John
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of GR860021B publication Critical patent/GR860021B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Seasonings (AREA)
GR860021A 1985-01-09 1986-01-07 Octahydro indolizine compounds useful as analgesics GR860021B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/689,883 US4582836A (en) 1985-01-09 1985-01-09 Octahydroindolizine compounds useful as analgesics

Publications (1)

Publication Number Publication Date
GR860021B true GR860021B (en) 1986-05-08

Family

ID=24770255

Family Applications (1)

Application Number Title Priority Date Filing Date
GR860021A GR860021B (en) 1985-01-09 1986-01-07 Octahydro indolizine compounds useful as analgesics

Country Status (16)

Country Link
US (1) US4582836A (el)
EP (1) EP0187711B1 (el)
JP (1) JPS61204182A (el)
CN (1) CN86100131A (el)
AT (1) ATE55907T1 (el)
CA (1) CA1255306A (el)
DE (1) DE3673657D1 (el)
DK (1) DK7286A (el)
ES (2) ES8703470A1 (el)
FI (1) FI860074A (el)
GR (1) GR860021B (el)
HU (1) HU195964B (el)
NO (1) NO860048L (el)
NZ (1) NZ214573A (el)
PH (1) PH21295A (el)
ZA (1) ZA86173B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689329A (en) * 1986-02-04 1987-08-25 Mcneilab, Inc. 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates
US4716172A (en) * 1986-04-10 1987-12-29 Mcneilab, Inc. 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates
US4683239A (en) * 1986-04-10 1987-07-28 Mcneilab, Inc. 3-diphenyl substituted octahydroindolizine analgesic compounds
US4800207A (en) * 1987-11-02 1989-01-24 Mcneilab, Inc. Hexahydropyrrolizine compounds useful as analgesics
AU653957B2 (en) * 1990-09-20 1994-10-20 Merrell Dow Pharmaceuticals Inc. 1-aryl-3-pyridinyl-2-propene-1-ones
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
US10533000B2 (en) 2011-05-26 2020-01-14 Sunovion Pharmaceuticals, Inc. Metabotrophic glutamate receptor 5 modulators and methods of use thereof

Also Published As

Publication number Publication date
DE3673657D1 (de) 1990-10-04
ES550742A0 (es) 1987-02-16
JPS61204182A (ja) 1986-09-10
HU195964B (en) 1988-08-29
ATE55907T1 (de) 1990-09-15
ES8707530A1 (es) 1987-08-01
EP0187711A2 (en) 1986-07-16
HUT41025A (en) 1987-03-30
EP0187711A3 (en) 1987-08-12
DK7286A (da) 1986-07-10
FI860074A0 (fi) 1986-01-08
US4582836A (en) 1986-04-15
EP0187711B1 (en) 1990-08-29
NO860048L (no) 1986-07-10
NZ214573A (en) 1988-04-29
ES8703470A1 (es) 1987-02-16
DK7286D0 (da) 1986-01-08
FI860074A (fi) 1986-07-10
ZA86173B (en) 1987-08-26
ES553207A0 (es) 1987-08-01
CN86100131A (zh) 1986-10-15
PH21295A (en) 1987-09-28
CA1255306A (en) 1989-06-06

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