ZA858385B - Fibrinolysis-enhancing agents - Google Patents
Fibrinolysis-enhancing agentsInfo
- Publication number
- ZA858385B ZA858385B ZA858385A ZA858385A ZA858385B ZA 858385 B ZA858385 B ZA 858385B ZA 858385 A ZA858385 A ZA 858385A ZA 858385 A ZA858385 A ZA 858385A ZA 858385 B ZA858385 B ZA 858385B
- Authority
- ZA
- South Africa
- Prior art keywords
- fibrinolysis
- enhancing agents
- enhancing
- agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59233567A JPS61112018A (ja) | 1984-11-06 | 1984-11-06 | 線溶増強剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA858385B true ZA858385B (en) | 1987-06-24 |
Family
ID=16957092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA858385A ZA858385B (en) | 1984-11-06 | 1985-10-31 | Fibrinolysis-enhancing agents |
Country Status (10)
Country | Link |
---|---|
US (1) | US5141947A (da) |
EP (1) | EP0181267B1 (da) |
JP (1) | JPS61112018A (da) |
AU (1) | AU581469B2 (da) |
CA (1) | CA1269617A (da) |
DE (1) | DE3582781D1 (da) |
DK (1) | DK171840B1 (da) |
IL (1) | IL76883A (da) |
NZ (1) | NZ213982A (da) |
ZA (1) | ZA858385B (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5242904A (en) * | 1987-06-05 | 1993-09-07 | The Dupont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
US5250720A (en) * | 1987-06-05 | 1993-10-05 | The Dupont Merck Pharmaceutical Company | Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases |
DE3804600A1 (de) * | 1988-02-13 | 1989-08-24 | Basf Ag | Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz |
GB8822147D0 (en) * | 1988-09-21 | 1988-10-26 | Ciba Geigy Ag | Pharmaceutically active combination |
DE3943241A1 (de) * | 1989-12-22 | 1991-06-27 | Schering Ag | Thrombolytisch wirkendes kombinationspraeparat |
US5506241A (en) * | 1992-03-18 | 1996-04-09 | Mitsubishi Chemical Corporation | Argatroban preparations for ophthalmic use |
US5371091A (en) * | 1992-08-31 | 1994-12-06 | Bristol-Myers Squibb Company | Heteroaromatic amine thrombin inhibitors |
JPH06219948A (ja) * | 1993-01-25 | 1994-08-09 | Mitsubishi Kasei Corp | 抗トロンビン剤及びその製造方法 |
US5840733A (en) * | 1996-07-01 | 1998-11-24 | Redcell, Canada, Inc. | Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes |
DE69928814T2 (de) * | 1998-09-03 | 2006-08-03 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Verwendung von TGF-Beta-Inhibitoren zum Behandeln von zerebralen Störungen |
WO2000054804A1 (en) * | 1999-03-16 | 2000-09-21 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh | Use of tgf-beta inhibitors for treating cerebral disorders |
WO2003080061A1 (en) * | 2002-03-21 | 2003-10-02 | Dana-Farber Cancer Institute, Inc. | Inhibition of cell death responses induced by oxidative stress |
CN100467022C (zh) * | 2007-04-13 | 2009-03-11 | 天津市炜杰科技有限公司 | 21(s)阿加曲班的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE786788A (fr) * | 1971-07-27 | 1973-01-26 | Rhone Poulenc Sa | Nouvelle enzyme thrombolytique et sa preparation par fermentation d'un streptomyces |
US3919414A (en) * | 1973-08-29 | 1975-11-11 | Abbott Lab | Accelerating the lysis of blood clots |
US4073916A (en) * | 1974-11-08 | 1978-02-14 | Mitsubishi Chemical Industries Limited | N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
NL7512637A (nl) * | 1974-11-08 | 1976-05-11 | Mitsubishi Chem Ind | Werkwijze ter bereiding van een geneesmiddel, het aldus gevormde geneesmiddel en werkwijze voor de bereiding van actieve component. |
US4258192A (en) * | 1977-12-16 | 1981-03-24 | Mitsubishi Chemical Industries Limited | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
IE48623B1 (en) * | 1978-08-31 | 1985-03-20 | Mitsubishi Chem Ind | Alpha-(n-arylsulfonyl-l-argininamides,processes for their preparation and pharmaceutical compositions containing these substances |
IT1170913B (it) * | 1981-04-23 | 1987-06-03 | Manetti & Roberts Italo Brit | Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche |
-
1984
- 1984-11-06 JP JP59233567A patent/JPS61112018A/ja active Granted
-
1985
- 1985-10-29 NZ NZ213982A patent/NZ213982A/xx unknown
- 1985-10-30 IL IL76883A patent/IL76883A/xx not_active IP Right Cessation
- 1985-10-30 AU AU49206/85A patent/AU581469B2/en not_active Ceased
- 1985-10-31 ZA ZA858385A patent/ZA858385B/xx unknown
- 1985-11-04 DK DK508485A patent/DK171840B1/da not_active IP Right Cessation
- 1985-11-06 CA CA000494713A patent/CA1269617A/en not_active Expired - Lifetime
- 1985-11-06 DE DE8585402134T patent/DE3582781D1/de not_active Expired - Fee Related
- 1985-11-06 EP EP85402134A patent/EP0181267B1/en not_active Expired - Lifetime
-
1991
- 1991-09-12 US US07/758,208 patent/US5141947A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3582781D1 (de) | 1991-06-13 |
EP0181267A2 (en) | 1986-05-14 |
EP0181267A3 (en) | 1989-02-22 |
DK171840B1 (da) | 1997-06-30 |
US5141947A (en) | 1992-08-25 |
JPS61112018A (ja) | 1986-05-30 |
EP0181267B1 (en) | 1991-05-08 |
AU581469B2 (en) | 1989-02-23 |
AU4920685A (en) | 1986-05-15 |
DK508485A (da) | 1986-05-07 |
NZ213982A (en) | 1989-06-28 |
IL76883A (en) | 1991-03-10 |
DK508485D0 (da) | 1985-11-04 |
JPH0114884B2 (da) | 1989-03-14 |
CA1269617A (en) | 1990-05-29 |
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