ZA852215B - A n-(6-substituted pyridine-2-carbonyl)-3-substituted histidine derivative,a method of preparing the same and its use as an antitumor agent - Google Patents

A n-(6-substituted pyridine-2-carbonyl)-3-substituted histidine derivative,a method of preparing the same and its use as an antitumor agent

Info

Publication number
ZA852215B
ZA852215B ZA852215A ZA852215A ZA852215B ZA 852215 B ZA852215 B ZA 852215B ZA 852215 A ZA852215 A ZA 852215A ZA 852215 A ZA852215 A ZA 852215A ZA 852215 B ZA852215 B ZA 852215B
Authority
ZA
South Africa
Prior art keywords
substituted
carbonyl
preparing
same
antitumor agent
Prior art date
Application number
ZA852215A
Other languages
English (en)
Inventor
Hamao Umezawa
Masaji Ohno
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of ZA852215B publication Critical patent/ZA852215B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA852215A 1984-03-26 1985-03-25 A n-(6-substituted pyridine-2-carbonyl)-3-substituted histidine derivative,a method of preparing the same and its use as an antitumor agent ZA852215B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59056138A JPS60199886A (ja) 1984-03-26 1984-03-26 Ν−(6−置換ピリジン−2−カルボニル)−3−置換ヒスチジン誘導体およびその製法

Publications (1)

Publication Number Publication Date
ZA852215B true ZA852215B (en) 1985-11-27

Family

ID=13018710

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA852215A ZA852215B (en) 1984-03-26 1985-03-25 A n-(6-substituted pyridine-2-carbonyl)-3-substituted histidine derivative,a method of preparing the same and its use as an antitumor agent

Country Status (10)

Country Link
EP (1) EP0158843B1 (de)
JP (1) JPS60199886A (de)
AT (1) ATE30723T1 (de)
DE (1) DE3560948D1 (de)
DK (1) DK133385A (de)
ES (1) ES8701751A1 (de)
GR (1) GR850735B (de)
HU (1) HU192918B (de)
PT (1) PT80161B (de)
ZA (1) ZA852215B (de)

Also Published As

Publication number Publication date
PT80161A (en) 1985-04-01
EP0158843B1 (de) 1987-11-11
GR850735B (de) 1985-07-19
HU192918B (en) 1987-07-28
JPS60199886A (ja) 1985-10-09
ATE30723T1 (de) 1987-11-15
PT80161B (en) 1987-04-28
ES541540A0 (es) 1986-12-01
JPH0376317B2 (de) 1991-12-05
DE3560948D1 (en) 1987-12-17
ES8701751A1 (es) 1986-12-01
DK133385A (da) 1985-09-27
DK133385D0 (da) 1985-03-25
HUT37918A (en) 1986-03-28
EP0158843A1 (de) 1985-10-23

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