ATE30723T1 - N-(6-substituiertes pyridin-2-carbonyl)-3substituiertes histidinderivat, verfahren zur herstellung und anwendung als antitumormittel. - Google Patents

N-(6-substituiertes pyridin-2-carbonyl)-3substituiertes histidinderivat, verfahren zur herstellung und anwendung als antitumormittel.

Info

Publication number
ATE30723T1
ATE30723T1 AT85103105T AT85103105T ATE30723T1 AT E30723 T1 ATE30723 T1 AT E30723T1 AT 85103105 T AT85103105 T AT 85103105T AT 85103105 T AT85103105 T AT 85103105T AT E30723 T1 ATE30723 T1 AT E30723T1
Authority
AT
Austria
Prior art keywords
carbonyl
tumorrow
agent
preparation
substituted pyridine
Prior art date
Application number
AT85103105T
Other languages
English (en)
Inventor
Hamao Prof Umezawa
Masaji Ohno
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Application granted granted Critical
Publication of ATE30723T1 publication Critical patent/ATE30723T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT85103105T 1984-03-26 1985-03-18 N-(6-substituiertes pyridin-2-carbonyl)-3substituiertes histidinderivat, verfahren zur herstellung und anwendung als antitumormittel. ATE30723T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59056138A JPS60199886A (ja) 1984-03-26 1984-03-26 Ν−（６−置換ピリジン−２−カルボニル）−３−置換ヒスチジン誘導体およびその製法
EP85103105A EP0158843B1 (de) 1984-03-26 1985-03-18 N-(6-substituiertes Pyridin-2-carbonyl)-3-substituiertes Histidinderivat, Verfahren zur Herstellung und Anwendung als Antitumormittel

Publications (1)

Publication Number Publication Date
ATE30723T1 true ATE30723T1 (de) 1987-11-15

Family

ID=13018710

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85103105T ATE30723T1 (de) 1984-03-26 1985-03-18 N-(6-substituiertes pyridin-2-carbonyl)-3substituiertes histidinderivat, verfahren zur herstellung und anwendung als antitumormittel.

Country Status (10)

Country Link
EP (1) EP0158843B1 (de)
JP (1) JPS60199886A (de)
AT (1) ATE30723T1 (de)
DE (1) DE3560948D1 (de)
DK (1) DK133385A (de)
ES (1) ES8701751A1 (de)
GR (1) GR850735B (de)
HU (1) HU192918B (de)
PT (1) PT80161B (de)
ZA (1) ZA852215B (de)

Also Published As

Publication number Publication date
DE3560948D1 (en) 1987-12-17
HU192918B (en) 1987-07-28
PT80161B (en) 1987-04-28
GR850735B (de) 1985-07-19
EP0158843A1 (de) 1985-10-23
ZA852215B (en) 1985-11-27
JPS60199886A (ja) 1985-10-09
PT80161A (en) 1985-04-01
JPH0376317B2 (de) 1991-12-05
ES8701751A1 (es) 1986-12-01
DK133385A (da) 1985-09-27
EP0158843B1 (de) 1987-11-11
ES541540A0 (es) 1986-12-01
DK133385D0 (da) 1985-03-25
HUT37918A (en) 1986-03-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee