ZA848024B - 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives useful as pharmaceuticals - Google Patents

4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives useful as pharmaceuticals

Info

Publication number
ZA848024B
ZA848024B ZA848024A ZA848024A ZA848024B ZA 848024 B ZA848024 B ZA 848024B ZA 848024 A ZA848024 A ZA 848024A ZA 848024 A ZA848024 A ZA 848024A ZA 848024 B ZA848024 B ZA 848024B
Authority
ZA
South Africa
Prior art keywords
alkyl
hydroxy
methyl
pharmaceuticals
phenyl
Prior art date
Application number
ZA848024A
Other languages
English (en)
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of ZA848024B publication Critical patent/ZA848024B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA848024A 1983-10-17 1984-10-15 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives useful as pharmaceuticals ZA848024B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8316485A FR2553413B1 (fr) 1983-10-17 1983-10-17 Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique

Publications (1)

Publication Number Publication Date
ZA848024B true ZA848024B (en) 1985-06-26

Family

ID=9293216

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA848024A ZA848024B (en) 1983-10-17 1984-10-15 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives useful as pharmaceuticals

Country Status (13)

Country Link
US (1) US4576944A (hu)
EP (1) EP0139590B1 (hu)
JP (1) JPS6097969A (hu)
AT (1) ATE35261T1 (hu)
AU (1) AU565778B2 (hu)
CA (1) CA1228354A (hu)
DE (1) DE3472256D1 (hu)
DK (1) DK157682C (hu)
ES (1) ES536991A0 (hu)
FR (1) FR2553413B1 (hu)
GR (1) GR80658B (hu)
IE (1) IE57773B1 (hu)
ZA (1) ZA848024B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8417170D0 (en) * 1984-07-05 1984-08-08 Wellcome Found Heterocyclic pharmaceutical compounds
GB8924528D0 (en) * 1989-10-31 1989-12-20 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
NZ561375A (en) * 2005-06-27 2011-06-30 Biovail Lab Int Srl Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound
AU2011255276B2 (en) 2010-05-21 2016-09-22 Research Triangle Institute Phenylmorpholines and analogues thereof
AU2011255456B2 (en) 2010-05-21 2017-01-19 Dignity Health Doing Business As St. Joseph's Hospital And Medical Center And Barrow Neurological Institute 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB791416A (en) * 1956-04-09 1958-03-05 Albert Boehringer Improvements in or relating to the production of substituted tetrahydrooxazines
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
US3225042A (en) * 1962-07-31 1965-12-21 Lilly Co Eli Hydroxymorpholines
US4044131A (en) * 1975-11-24 1977-08-23 American Home Products Corporation 2-Morpholinol derivatives

Also Published As

Publication number Publication date
JPH0522704B2 (hu) 1993-03-30
DK484684D0 (da) 1984-10-10
US4576944A (en) 1986-03-18
CA1228354A (fr) 1987-10-20
AU3409184A (en) 1985-04-26
IE57773B1 (en) 1993-04-07
EP0139590A3 (en) 1985-06-26
ES8507123A1 (es) 1985-08-16
AU565778B2 (en) 1987-09-24
FR2553413B1 (fr) 1986-03-21
EP0139590B1 (fr) 1988-06-22
GR80658B (en) 1985-02-18
IE842552L (en) 1985-04-17
DE3472256D1 (en) 1988-07-28
ES536991A0 (es) 1985-08-16
DK484684A (da) 1985-04-18
EP0139590A2 (fr) 1985-05-02
JPS6097969A (ja) 1985-05-31
DK157682C (da) 1990-07-09
ATE35261T1 (de) 1988-07-15
FR2553413A1 (fr) 1985-04-19
DK157682B (da) 1990-02-05

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