ZA845308B - Endo-8,8-dialkyl-8-azoniabicyclo(3.2.1)octane-6,7-exo-epoxy-3-alkyl-carboxylate salts,a process for their preparation,and therapeutic compositions which contain them as active principle - Google Patents

Endo-8,8-dialkyl-8-azoniabicyclo(3.2.1)octane-6,7-exo-epoxy-3-alkyl-carboxylate salts,a process for their preparation,and therapeutic compositions which contain them as active principle

Info

Publication number
ZA845308B
ZA845308B ZA845308A ZA845308A ZA845308B ZA 845308 B ZA845308 B ZA 845308B ZA 845308 A ZA845308 A ZA 845308A ZA 845308 A ZA845308 A ZA 845308A ZA 845308 B ZA845308 B ZA 845308B
Authority
ZA
South Africa
Prior art keywords
sub
azoniabicyclo
exo
octane
dialkyl
Prior art date
Application number
ZA845308A
Other languages
English (en)
Inventor
Virgilio Bernareggi
Roberto Margutti
Fausto Bonifacio
Maurizio Fano
Original Assignee
Valeas Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeas Spa filed Critical Valeas Spa
Publication of ZA845308B publication Critical patent/ZA845308B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA845308A 1983-07-26 1984-07-10 Endo-8,8-dialkyl-8-azoniabicyclo(3.2.1)octane-6,7-exo-epoxy-3-alkyl-carboxylate salts,a process for their preparation,and therapeutic compositions which contain them as active principle ZA845308B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22238/83A IT1194343B (it) 1983-07-26 1983-07-26 Sali di endo-8,8-dialchil-8-azoniabiciclo (3.2.1) ottan-6,7-esso-epossi-3-alchilcarbossilati,processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Publications (1)

Publication Number Publication Date
ZA845308B true ZA845308B (en) 1985-02-27

Family

ID=11193504

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845308A ZA845308B (en) 1983-07-26 1984-07-10 Endo-8,8-dialkyl-8-azoniabicyclo(3.2.1)octane-6,7-exo-epoxy-3-alkyl-carboxylate salts,a process for their preparation,and therapeutic compositions which contain them as active principle

Country Status (11)

Country Link
US (1) US4558054A (da)
EP (1) EP0133218B1 (da)
JP (1) JPS6042382A (da)
AT (1) ATE38989T1 (da)
AU (1) AU562763B2 (da)
CA (1) CA1248956A (da)
DE (1) DE3475402D1 (da)
DK (1) DK162285C (da)
IT (1) IT1194343B (da)
NZ (1) NZ208857A (da)
ZA (1) ZA845308B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190133B (it) * 1986-06-19 1988-02-10 Chiesi Farma Spa Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
US6706726B2 (en) * 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2962499A (en) * 1957-07-03 1960-11-29 Endo Lab Certain esters of tropine and tropinium salts
DE1795818C2 (de) * 1966-01-26 1980-07-10 C.H. Boehringer Sohn, 6507 Ingelheim Quartärsalze des N-Äthylnorscopolamin
DE1670048C3 (de) * 1966-01-26 1980-09-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue Norscopolaminderivate
GB1413484A (en) * 1972-04-18 1975-11-12 Angeli Inst Spa Scopolamine derivatives
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Also Published As

Publication number Publication date
ATE38989T1 (de) 1988-12-15
DE3475402D1 (en) 1989-01-05
DK363284D0 (da) 1984-07-25
US4558054A (en) 1985-12-10
IT8322238A0 (it) 1983-07-26
DK162285B (da) 1991-10-07
EP0133218B1 (en) 1988-11-30
DK363284A (da) 1985-01-27
EP0133218A2 (en) 1985-02-20
CA1248956A (en) 1989-01-17
JPH0331199B2 (da) 1991-05-02
DK162285C (da) 1992-03-02
AU3116384A (en) 1985-01-31
AU562763B2 (en) 1987-06-18
IT8322238A1 (it) 1985-01-26
NZ208857A (en) 1988-05-30
JPS6042382A (ja) 1985-03-06
EP0133218A3 (en) 1986-12-30
IT1194343B (it) 1988-09-14

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