ZA844162B - Pyrazole derivatives with an ergoline skeleton,their acid addition salts,and a process for the preparation thereof - Google Patents

Pyrazole derivatives with an ergoline skeleton,their acid addition salts,and a process for the preparation thereof

Info

Publication number
ZA844162B
ZA844162B ZA844162A ZA844162A ZA844162B ZA 844162 B ZA844162 B ZA 844162B ZA 844162 A ZA844162 A ZA 844162A ZA 844162 A ZA844162 A ZA 844162A ZA 844162 B ZA844162 B ZA 844162B
Authority
ZA
South Africa
Prior art keywords
preparation
acid addition
addition salts
pyrazole derivatives
ergoline skeleton
Prior art date
Application number
ZA844162A
Other languages
English (en)
Inventor
Tivadar Rettegi
Erzsebet Mago-Karacsony
Lajos Toldy
Jozsef Borsy
Ilona Berzetei
Andrias Ronai
Aliz Druga
Gyoergy Cseh
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA844162B publication Critical patent/ZA844162B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA844162A 1983-06-03 1984-06-04 Pyrazole derivatives with an ergoline skeleton,their acid addition salts,and a process for the preparation thereof ZA844162B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU832001A HU190105B (en) 1983-06-03 1983-06-03 Process for production of pirazolyl-methyl-ergolin- derivatives and their acid additional salts

Publications (1)

Publication Number Publication Date
ZA844162B true ZA844162B (en) 1984-12-24

Family

ID=10957235

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA844162A ZA844162B (en) 1983-06-03 1984-06-04 Pyrazole derivatives with an ergoline skeleton,their acid addition salts,and a process for the preparation thereof

Country Status (15)

Country Link
US (1) US4632928A (de)
EP (1) EP0128479B1 (de)
JP (1) JPS6084286A (de)
AR (1) AR240323A1 (de)
AT (1) ATE55129T1 (de)
AU (1) AU569518B2 (de)
CA (1) CA1252086A (de)
DE (1) DE3482854D1 (de)
DK (1) DK162050C (de)
ES (1) ES8800940A1 (de)
FI (1) FI80272C (de)
GR (1) GR82419B (de)
HU (1) HU190105B (de)
IL (1) IL71988A (de)
ZA (1) ZA844162B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
GB9603226D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Heterocyclyl-ergoline derivatives
US6369089B1 (en) 2000-09-14 2002-04-09 Allergan Sales, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US6407250B1 (en) 2000-09-14 2002-06-18 Allergan Sales, Inc. Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US7045634B2 (en) * 2003-09-05 2006-05-16 Allergan, Inc. Prostamide receptor antagonists
AU2010232556A1 (en) * 2009-04-02 2011-11-03 Allergan, Inc. Prostaglandin E receptor antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695752C3 (de) * 1966-07-29 1974-06-06 Societa Farmaceutici Italia, Mailand (Italien) 1 ,ö-Dimethyl-ebeta-N-carbobenzoxyaminomethyl-2,3-dihydro-1 Oalpha-ergolin und ein Verfahren zu seiner Herstellung
US4134987A (en) * 1976-01-14 1979-01-16 Huppatz John L Compounds and compositions
HU178396B (en) * 1978-03-20 1982-04-28 Vianova Kunstharz Ag Process for producing new 8-beta-hydrazion-methyl-ergoline-and -ergolene derivatives
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
ES533086A0 (es) 1987-12-01
IL71988A (en) 1987-01-30
DK162050C (da) 1992-02-10
FI842233A (fi) 1984-12-04
JPS6084286A (ja) 1985-05-13
CA1252086A (en) 1989-04-04
FI842233A0 (fi) 1984-06-04
US4632928A (en) 1986-12-30
EP0128479B1 (de) 1990-08-01
HU190105B (en) 1986-08-28
FI80272C (fi) 1990-05-10
AU2903284A (en) 1984-12-06
AR240323A1 (es) 1990-03-30
JPH0342274B2 (de) 1991-06-26
DK273884D0 (da) 1984-06-01
IL71988A0 (en) 1984-10-31
EP0128479A3 (en) 1985-10-30
DK162050B (da) 1991-09-09
ATE55129T1 (de) 1990-08-15
EP0128479A2 (de) 1984-12-19
DK273884A (da) 1984-12-04
GR82419B (de) 1984-12-13
HUT34748A (en) 1985-04-28
DE3482854D1 (de) 1990-09-06
FI80272B (fi) 1990-01-31
AU569518B2 (en) 1988-02-04
ES8800940A1 (es) 1987-12-01

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