ZA84394B - Pyrazino(2',3'-3,4)pyrido(1,2-a)indole derivatives - Google Patents

Pyrazino(2',3'-3,4)pyrido(1,2-a)indole derivatives

Info

Publication number
ZA84394B
ZA84394B ZA84394A ZA84394A ZA84394B ZA 84394 B ZA84394 B ZA 84394B ZA 84394 A ZA84394 A ZA 84394A ZA 84394 A ZA84394 A ZA 84394A ZA 84394 B ZA84394 B ZA 84394B
Authority
ZA
South Africa
Prior art keywords
pyrazino
pyrido
indole derivatives
indole
derivatives
Prior art date
Application number
ZA84394A
Other languages
English (en)
Inventor
George Santroch
Ivo Jirkovsky
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA84394B publication Critical patent/ZA84394B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA84394A 1983-01-26 1984-01-18 Pyrazino(2',3'-3,4)pyrido(1,2-a)indole derivatives ZA84394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/461,095 US4482714A (en) 1983-01-26 1983-01-26 Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives

Publications (1)

Publication Number Publication Date
ZA84394B true ZA84394B (en) 1985-09-25

Family

ID=23831210

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84394A ZA84394B (en) 1983-01-26 1984-01-18 Pyrazino(2',3'-3,4)pyrido(1,2-a)indole derivatives

Country Status (10)

Country Link
US (1) US4482714A (de)
EP (1) EP0115920A3 (de)
JP (1) JPS59141580A (de)
KR (1) KR840007227A (de)
AU (1) AU2376884A (de)
DK (1) DK33684A (de)
ES (1) ES8707532A1 (de)
GR (1) GR81736B (de)
IE (1) IE840119L (de)
ZA (1) ZA84394B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515949A (en) * 1983-01-26 1985-05-07 American Home Products Corporation [2-(1H-indol-1-yl)ethyl]-2-piperazine and pyrido[1,2-a]indol-9-one as intermediates for pyrazino(2,3-3,4)pyrido(1,2-a) indoles which are useful for treating hypertension in mammals
US4624954A (en) * 1985-12-20 1986-11-25 American Home Products Corporation 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments
US4665183A (en) * 1985-12-20 1987-05-12 American Home Products Corp. Process for preparing 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof useful for the treatment of cognitive impairments
US7297289B2 (en) * 2001-03-26 2007-11-20 Nisshinbo Industries, Inc. Ionic liquids, electrolyte salts for storage device, electrolytic solution for storage device, electric double layer capacitor, and secondary battery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3644384A (en) * 1969-06-09 1972-02-22 Sterling Drug Inc Certain 2-(alpha-haloacetyl) - 1 2 3 4-tetrahydro - 9h - pyrido(3 4-b)indole-3-carboxylates and derivatives
US3850934A (en) * 1973-06-08 1974-11-26 Hoffmann La Roche 6,7,8,9-tetrahydro-7a,11a-ethanooxyindolo(1,2-h)(1,7)naphthyridin-10(11h)-ones
DE2703920A1 (de) * 1976-02-05 1977-08-11 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung

Also Published As

Publication number Publication date
US4482714A (en) 1984-11-13
GR81736B (de) 1984-12-12
DK33684A (da) 1984-07-27
IE840119L (en) 1984-07-26
EP0115920A2 (de) 1984-08-15
JPS59141580A (ja) 1984-08-14
ES529131A0 (es) 1985-11-16
AU2376884A (en) 1984-08-02
ES8707532A1 (es) 1985-11-16
DK33684D0 (da) 1984-01-25
EP0115920A3 (de) 1986-02-05
KR840007227A (ko) 1984-12-06

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