ZA842753B - 2-dihydropyrrolyl-cycloalkyl-amide analgesics - Google Patents

2-dihydropyrrolyl-cycloalkyl-amide analgesics

Info

Publication number
ZA842753B
ZA842753B ZA842753A ZA842753A ZA842753B ZA 842753 B ZA842753 B ZA 842753B ZA 842753 A ZA842753 A ZA 842753A ZA 842753 A ZA842753 A ZA 842753A ZA 842753 B ZA842753 B ZA 842753B
Authority
ZA
South Africa
Prior art keywords
dihydropyrrolyl
analgesics
cycloalkyl
amide
amide analgesics
Prior art date
Application number
ZA842753A
Other languages
English (en)
Inventor
Jacob Szmuszkovicz
John Michael Mccall
Lester Jay Kaplan
Moses William Mcmillan
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ZA842753B publication Critical patent/ZA842753B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA842753A 1983-05-18 1984-04-12 2-dihydropyrrolyl-cycloalkyl-amide analgesics ZA842753B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49585783A 1983-05-18 1983-05-18

Publications (1)

Publication Number Publication Date
ZA842753B true ZA842753B (en) 1984-11-28

Family

ID=23970261

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA842753A ZA842753B (en) 1983-05-18 1984-04-12 2-dihydropyrrolyl-cycloalkyl-amide analgesics

Country Status (4)

Country Link
EP (1) EP0126612B1 (xx)
JP (1) JPS59222469A (xx)
DE (1) DE3465472D1 (xx)
ZA (1) ZA842753B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8618188D0 (en) * 1986-07-25 1986-09-03 Ici Plc Diamine compounds
US5229414A (en) * 1988-01-21 1993-07-20 Imperial Chemical Industries Plc Diamine compounds
GB8801304D0 (en) * 1988-01-21 1988-02-17 Ici Plc Diamine compounds
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
WO1993003382A2 (en) * 1991-08-01 1993-02-18 Pharmaceutical Discovery Corporation Characterization of specific drug receptors with fluorescent ligands
US5576436A (en) * 1991-08-01 1996-11-19 Pharmaceutical Discovery Corporation Fluorescent ligands
ES2319265T3 (es) * 2001-03-30 2009-05-06 Toray Industries, Inc. Farmacos para el sindrome de piernas inquietas.
GB2572335B (en) * 2018-03-26 2022-09-28 Equinor Energy As Subsea well installation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065573A (en) * 1976-06-03 1977-12-27 The Upjohn Company 4-Amino-4-phenylcyclohexanone ketal compositions and process of use
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4212878A (en) * 1978-01-26 1980-07-15 The Upjohn Company Phenylacetamide derivative analgesics
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics
US4360531A (en) * 1981-04-09 1982-11-23 The Upjohn Company Substituted cycloalkanes

Also Published As

Publication number Publication date
DE3465472D1 (de) 1987-09-24
EP0126612B1 (en) 1987-08-19
EP0126612A1 (en) 1984-11-28
JPS59222469A (ja) 1984-12-14

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