DE3465472D1 - 3,4-dichloro-n-û2-(2,5-dihydro-1h-pyrrol-1-yl)cyclohexyl¨-n-methylbenzeneacetamide - Google Patents

3,4-dichloro-n-û2-(2,5-dihydro-1h-pyrrol-1-yl)cyclohexyl¨-n-methylbenzeneacetamide

Info

Publication number
DE3465472D1
DE3465472D1 DE8484303277T DE3465472T DE3465472D1 DE 3465472 D1 DE3465472 D1 DE 3465472D1 DE 8484303277 T DE8484303277 T DE 8484303277T DE 3465472 T DE3465472 T DE 3465472T DE 3465472 D1 DE3465472 D1 DE 3465472D1
Authority
DE
Germany
Prior art keywords
methylbeneene
pyrrol
acetamide
dichloro
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484303277T
Other languages
English (en)
Inventor
Jacob Szmuszkovicz
John Michael Mccall
Lester Jay Kaplan
Moses William Mcmillan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DE3465472D1 publication Critical patent/DE3465472D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
DE8484303277T 1983-05-18 1984-05-15 3,4-dichloro-n-û2-(2,5-dihydro-1h-pyrrol-1-yl)cyclohexyl¨-n-methylbenzeneacetamide Expired DE3465472D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49585783A 1983-05-18 1983-05-18

Publications (1)

Publication Number Publication Date
DE3465472D1 true DE3465472D1 (de) 1987-09-24

Family

ID=23970261

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484303277T Expired DE3465472D1 (de) 1983-05-18 1984-05-15 3,4-dichloro-n-û2-(2,5-dihydro-1h-pyrrol-1-yl)cyclohexyl¨-n-methylbenzeneacetamide

Country Status (4)

Country Link
EP (1) EP0126612B1 (de)
JP (1) JPS59222469A (de)
DE (1) DE3465472D1 (de)
ZA (1) ZA842753B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8618188D0 (en) * 1986-07-25 1986-09-03 Ici Plc Diamine compounds
US5229414A (en) * 1988-01-21 1993-07-20 Imperial Chemical Industries Plc Diamine compounds
GB8801304D0 (en) * 1988-01-21 1988-02-17 Ici Plc Diamine compounds
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
WO1993003382A2 (en) * 1991-08-01 1993-02-18 Pharmaceutical Discovery Corporation Characterization of specific drug receptors with fluorescent ligands
US5576436A (en) * 1991-08-01 1996-11-19 Pharmaceutical Discovery Corporation Fluorescent ligands
CN100398154C (zh) 2001-03-30 2008-07-02 东丽株式会社 精神神经疾病治疗药
GB2572335B (en) * 2018-03-26 2022-09-28 Equinor Energy As Subsea well installation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065573A (en) * 1976-06-03 1977-12-27 The Upjohn Company 4-Amino-4-phenylcyclohexanone ketal compositions and process of use
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4212878A (en) * 1978-01-26 1980-07-15 The Upjohn Company Phenylacetamide derivative analgesics
US4360531A (en) * 1981-04-09 1982-11-23 The Upjohn Company Substituted cycloalkanes
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics

Also Published As

Publication number Publication date
EP0126612A1 (de) 1984-11-28
JPS59222469A (ja) 1984-12-14
ZA842753B (en) 1984-11-28
EP0126612B1 (de) 1987-08-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee