ZA8410113B - New 1,4-naphthoquinone derivatives,a process for their preparation and their use as medicaments - Google Patents

New 1,4-naphthoquinone derivatives,a process for their preparation and their use as medicaments

Info

Publication number
ZA8410113B
ZA8410113B ZA8410113A ZA8410113A ZA8410113B ZA 8410113 B ZA8410113 B ZA 8410113B ZA 8410113 A ZA8410113 A ZA 8410113A ZA 8410113 A ZA8410113 A ZA 8410113A ZA 8410113 B ZA8410113 B ZA 8410113B
Authority
ZA
South Africa
Prior art keywords
medicaments
preparation
new
naphthoquinone derivatives
naphthoquinone
Prior art date
Application number
ZA8410113A
Other languages
English (en)
Inventor
Romanis Fruchtmann
Harald Horstmann
Bodo Junge
Udo Krupka
Wolfgang Opitz
Bernhard Pelster
Walter Gauss
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of ZA8410113B publication Critical patent/ZA8410113B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C07C225/26Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
    • C07C225/30Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
ZA8410113A 1983-12-31 1984-12-28 New 1,4-naphthoquinone derivatives,a process for their preparation and their use as medicaments ZA8410113B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833347657 DE3347657A1 (de) 1983-12-31 1983-12-31 Neue 1,4-naphthochinonderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA8410113B true ZA8410113B (en) 1985-08-28

Family

ID=6218507

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8410113A ZA8410113B (en) 1983-12-31 1984-12-28 New 1,4-naphthoquinone derivatives,a process for their preparation and their use as medicaments

Country Status (13)

Country Link
EP (1) EP0149818A3 (fr)
JP (1) JPS60158150A (fr)
KR (1) KR850004578A (fr)
AU (1) AU3659484A (fr)
DE (1) DE3347657A1 (fr)
DK (1) DK627684A (fr)
ES (1) ES8605765A1 (fr)
FI (1) FI845125L (fr)
GR (1) GR82623B (fr)
IL (1) IL73964A0 (fr)
NO (1) NO844984L (fr)
PT (1) PT79779B (fr)
ZA (1) ZA8410113B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686220A (en) * 1985-12-19 1987-08-11 American Cyanamid Company Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals
US4692449A (en) * 1986-06-20 1987-09-08 American Cyanamid Company Substituted quinolinediones
FR2742151B1 (fr) * 1995-12-12 1998-03-06 Innothera Lab Sa Utilisation de derives de bicycles mono ou dicetoniques, nouveaux composes obtenus et leur application en therapeutique
GB2309455A (en) * 1996-01-26 1997-07-30 Dong Kook Pharm Co Ltd 2-Chloro-3-arylamino-1,4-naphthoquinone derivatives, process for their preparation and their use as an agent for inhibiting platelet aggregation
CN104447265B (zh) * 2014-12-05 2016-08-24 中国科学院昆明植物研究所 醌类化合物及其制备方法与其用作为杀线虫农药
CN109521148A (zh) * 2019-01-25 2019-03-26 四川双启检测技术有限公司 一种检测甲萘醌中1,4-萘醌含量的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1314881A (en) * 1970-03-06 1973-04-26 Shell Int Research Naphthaquinone derivatives and their use as herbicides
JPS54119027A (en) * 1978-03-07 1979-09-14 Ube Ind Ltd Agricultural and horticultural microbicide

Also Published As

Publication number Publication date
PT79779A (en) 1985-01-01
NO844984L (no) 1985-07-01
ES538806A0 (es) 1986-04-01
AU3659484A (en) 1985-07-04
DK627684D0 (da) 1984-12-21
JPS60158150A (ja) 1985-08-19
FI845125A0 (fi) 1984-12-27
IL73964A0 (en) 1985-03-31
EP0149818A3 (fr) 1986-12-17
KR850004578A (ko) 1985-07-25
DK627684A (da) 1985-07-01
FI845125L (fi) 1985-07-01
EP0149818A2 (fr) 1985-07-31
GR82623B (en) 1985-05-07
ES8605765A1 (es) 1986-04-01
DE3347657A1 (de) 1985-07-11
PT79779B (en) 1986-10-21

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