ZA826634B - 3-phenoxypropan-2-ol derivatives - Google Patents
3-phenoxypropan-2-ol derivativesInfo
- Publication number
- ZA826634B ZA826634B ZA826634A ZA826634A ZA826634B ZA 826634 B ZA826634 B ZA 826634B ZA 826634 A ZA826634 A ZA 826634A ZA 826634 A ZA826634 A ZA 826634A ZA 826634 B ZA826634 B ZA 826634B
- Authority
- ZA
- South Africa
- Prior art keywords
- phenoxypropan
- derivatives
- radical
- glaucoma
- tert
- Prior art date
Links
- IBLKWZIFZMJLFL-UHFFFAOYSA-N 1-phenoxypropan-2-ol Chemical class CC(O)COC1=CC=CC=C1 IBLKWZIFZMJLFL-UHFFFAOYSA-N 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- -1 cycloalkyl radical Chemical group 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C43/196—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8117137A FR2512443A1 (fr) | 1981-09-10 | 1981-09-10 | Derives de phenoxy-3 propanol-2, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA826634B true ZA826634B (en) | 1983-07-27 |
Family
ID=9262031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA826634A ZA826634B (en) | 1981-09-10 | 1982-09-09 | 3-phenoxypropan-2-ol derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4515814A (OSRAM) |
| EP (1) | EP0074873B1 (OSRAM) |
| JP (1) | JPS5859947A (OSRAM) |
| AT (1) | ATE10361T1 (OSRAM) |
| AU (1) | AU553411B2 (OSRAM) |
| CA (1) | CA1202984A (OSRAM) |
| DE (1) | DE3261297D1 (OSRAM) |
| ES (2) | ES8400731A1 (OSRAM) |
| FR (1) | FR2512443A1 (OSRAM) |
| GR (1) | GR77673B (OSRAM) |
| IE (1) | IE53784B1 (OSRAM) |
| IL (1) | IL66757A (OSRAM) |
| NZ (1) | NZ201859A (OSRAM) |
| PT (1) | PT75533B (OSRAM) |
| ZA (1) | ZA826634B (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3151201A1 (de) * | 1981-12-23 | 1983-07-28 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte |
| US4634713A (en) * | 1982-05-28 | 1987-01-06 | Ciba-Geigy Corporation | Antihypertensive 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives |
| GB8510146D0 (en) * | 1985-04-20 | 1985-05-30 | Smith Kline French Lab | Chemical compounds & processes |
| US4665094A (en) * | 1985-08-29 | 1987-05-12 | Merck & Co., Inc. | Oculoselective beta-blockers for treatment of elevated intraocular pressure |
| US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
| ES2011584A6 (es) * | 1989-05-26 | 1990-01-16 | Esteve Quimica Sa | Procedimiento industrial para la obtencion de una ariloxipropanolamina. |
| AU4219897A (en) * | 1996-09-18 | 1998-04-14 | Daiso Co. Ltd. | Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers |
| CN115785058B (zh) * | 2022-12-09 | 2024-05-03 | 广州康瑞泰药业有限公司 | 一种合成替格瑞洛五元环中间体的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA956632A (en) * | 1969-05-16 | 1974-10-22 | Yoshitomi Pharmaceutical Industries | Phenoxy-aminopropanol derivatives |
| FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| DE2645710C2 (de) * | 1976-10-09 | 1985-06-27 | Merck Patent Gmbh, 6100 Darmstadt | Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung |
| FR2409980A1 (fr) * | 1977-11-24 | 1979-06-22 | Synthelabo | Ethers de phenols et leur application en therapeutique |
-
1981
- 1981-09-10 FR FR8117137A patent/FR2512443A1/fr active Granted
-
1982
- 1982-08-25 AT AT82401583T patent/ATE10361T1/de not_active IP Right Cessation
- 1982-08-25 DE DE8282401583T patent/DE3261297D1/de not_active Expired
- 1982-08-25 EP EP82401583A patent/EP0074873B1/fr not_active Expired
- 1982-08-30 US US06/412,962 patent/US4515814A/en not_active Expired - Fee Related
- 1982-09-09 IE IE2214/82A patent/IE53784B1/en unknown
- 1982-09-09 NZ NZ201859A patent/NZ201859A/en unknown
- 1982-09-09 ES ES515588A patent/ES8400731A1/es not_active Expired
- 1982-09-09 CA CA000411047A patent/CA1202984A/en not_active Expired
- 1982-09-09 AU AU88166/82A patent/AU553411B2/en not_active Ceased
- 1982-09-09 IL IL66757A patent/IL66757A/xx unknown
- 1982-09-09 ZA ZA826634A patent/ZA826634B/xx unknown
- 1982-09-09 JP JP57157940A patent/JPS5859947A/ja active Pending
- 1982-09-09 GR GR69244A patent/GR77673B/el unknown
- 1982-09-09 PT PT75533A patent/PT75533B/pt unknown
-
1983
- 1983-06-30 ES ES523719A patent/ES8403854A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES515588A0 (es) | 1983-11-01 |
| AU8816682A (en) | 1983-03-31 |
| FR2512443A1 (fr) | 1983-03-11 |
| PT75533B (fr) | 1985-12-09 |
| IL66757A (en) | 1985-12-31 |
| ES523719A0 (es) | 1984-04-01 |
| US4515814A (en) | 1985-05-07 |
| ES8400731A1 (es) | 1983-11-01 |
| NZ201859A (en) | 1985-05-31 |
| DE3261297D1 (en) | 1985-01-03 |
| CA1202984A (en) | 1986-04-08 |
| IE822214L (en) | 1983-03-10 |
| PT75533A (fr) | 1982-10-01 |
| ATE10361T1 (de) | 1984-12-15 |
| GR77673B (OSRAM) | 1984-09-25 |
| IL66757A0 (en) | 1982-12-31 |
| ES8403854A1 (es) | 1984-04-01 |
| JPS5859947A (ja) | 1983-04-09 |
| IE53784B1 (en) | 1989-02-15 |
| AU553411B2 (en) | 1986-07-17 |
| EP0074873A1 (fr) | 1983-03-23 |
| FR2512443B1 (OSRAM) | 1984-07-13 |
| EP0074873B1 (fr) | 1984-11-21 |
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