ZA822083B - N-substituted-amido-amino acids - Google Patents

N-substituted-amido-amino acids

Info

Publication number
ZA822083B
ZA822083B ZA822083A ZA822083A ZA822083B ZA 822083 B ZA822083 B ZA 822083B ZA 822083 A ZA822083 A ZA 822083A ZA 822083 A ZA822083 A ZA 822083A ZA 822083 B ZA822083 B ZA 822083B
Authority
ZA
South Africa
Prior art keywords
alkyl
carbon atoms
lower alkoxy
amino
heterocyclic
Prior art date
Application number
ZA822083A
Other languages
English (en)
Inventor
J Skiles
R Youssefyeh
J Suh
H Jones
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of ZA822083B publication Critical patent/ZA822083B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA822083A 1981-03-30 1982-03-26 N-substituted-amido-amino acids ZA822083B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24905381A 1981-03-30 1981-03-30

Publications (1)

Publication Number Publication Date
ZA822083B true ZA822083B (en) 1983-02-23

Family

ID=22941861

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA822083A ZA822083B (en) 1981-03-30 1982-03-26 N-substituted-amido-amino acids

Country Status (10)

Country Link
EP (1) EP0061768B1 (de)
JP (1) JPS57175152A (de)
KR (1) KR830008998A (de)
AT (1) ATE19782T1 (de)
AU (1) AU556932B2 (de)
DE (1) DE3271116D1 (de)
IL (1) IL65347A (de)
NZ (1) NZ200162A (de)
PH (3) PH20083A (de)
ZA (1) ZA822083B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
US4686295A (en) * 1982-03-10 1987-08-11 Usv Pharmaceutical Corporation N-carboxy anhydride intermediates
US4482544A (en) * 1982-11-29 1984-11-13 Usv Pharmaceutical Corporation Compounds for treating hypertension
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd N−〔1(s)−エトキシカルボニル−3−フエニルプロピル〕−l−アラニル−l−プロリンの製造法
US4888427A (en) * 1987-04-07 1989-12-19 University Of Florida Amino acids containing dihydropyridine ring systems for site-specific delivery of peptides to the brain
US5079366A (en) * 1987-04-07 1992-01-07 University Of Florida Quarternary pyridinium salts
FR2626279B1 (fr) * 1988-01-26 1990-07-13 Roussel Uclaf Nouveaux derives de l'indolo(3,2,1-de)(1,4)-oxazino(2,3,4-ij)(1,5) naphthyridine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
US7973173B2 (en) 2005-07-05 2011-07-05 Cipla Limited Process for the synthesis of an ACE inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides

Also Published As

Publication number Publication date
DE3271116D1 (de) 1986-06-19
AU8170682A (en) 1982-10-07
EP0061768B1 (de) 1986-05-14
PH21632A (en) 1988-01-13
NZ200162A (en) 1985-08-16
PH20083A (en) 1986-09-24
AU556932B2 (en) 1986-11-27
ATE19782T1 (de) 1986-05-15
KR830008998A (ko) 1983-12-16
IL65347A (en) 1987-12-31
JPS57175152A (en) 1982-10-28
PH21449A (en) 1987-10-28
EP0061768A1 (de) 1982-10-06
IL65347A0 (en) 1982-05-31
JPH0448800B2 (de) 1992-08-07

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