ZA811386B - 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, their use and preparation - Google Patents

7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, their use and preparation

Info

Publication number
ZA811386B
ZA811386B ZA00811386A ZA811386A ZA811386B ZA 811386 B ZA811386 B ZA 811386B ZA 00811386 A ZA00811386 A ZA 00811386A ZA 811386 A ZA811386 A ZA 811386A ZA 811386 B ZA811386 B ZA 811386B
Authority
ZA
South Africa
Prior art keywords
azabicyclo
hept
ene
oxo
preparation
Prior art date
Application number
ZA00811386A
Other languages
English (en)
Inventor
Tetsuo Hiraoka
Hiraoka Tetsuo
Takeo Kobayashi
Kobayashi Takeo
Noboru Ishida
Ishida Noboru
Shinichi Sugawara
Sugawara Shinichi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of ZA811386B publication Critical patent/ZA811386B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA00811386A 1980-03-03 1981-03-03 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, their use and preparation ZA811386B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2625480A JPS56122379A (en) 1980-03-03 1980-03-03 1-carba-2-penem-3-carboxylic acid derivative

Publications (1)

Publication Number Publication Date
ZA811386B true ZA811386B (en) 1982-04-28

Family

ID=12188121

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00811386A ZA811386B (en) 1980-03-03 1981-03-03 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, their use and preparation

Country Status (15)

Country Link
US (1) US4377591A (en:Method)
JP (1) JPS56122379A (en:Method)
AU (1) AU6795681A (en:Method)
BE (1) BE887752A (en:Method)
DD (1) DD156911A5 (en:Method)
DE (1) DE3107854A1 (en:Method)
DK (1) DK93481A (en:Method)
ES (1) ES500032A0 (en:Method)
FR (1) FR2477147B1 (en:Method)
GB (1) GB2071656B (en:Method)
IT (1) IT8167300A0 (en:Method)
NL (1) NL8101039A (en:Method)
PL (1) PL229973A1 (en:Method)
SE (1) SE8101323L (en:Method)
ZA (1) ZA811386B (en:Method)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1179675A (en) * 1981-01-30 1984-12-18 Erwin Gotschi 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
US4680292A (en) * 1984-12-13 1987-07-14 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent
EP0184844A1 (en) * 1984-12-13 1986-06-18 Merck & Co. Inc. 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge
US4725594A (en) * 1984-12-13 1988-02-16 Merck & Co., Inc. Carbapenems having an internally or externally alkylated mono- or bicyclic 2-quaternary heteroarylalxyl heteromethyl substituent
EP0186057A1 (en) * 1984-12-13 1986-07-02 Merck & Co. Inc. Carbapenems having a 2-position substituent joined through an alkyleneheteroatom bridge
US4729993A (en) * 1984-12-13 1988-03-08 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl substituent
US5068232A (en) * 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
JPH05305570A (ja) * 1992-11-25 1993-11-19 Hitachi Ltd 研磨部材
JPH05305569A (ja) * 1992-11-25 1993-11-19 Hitachi Ltd 表面研磨方法
US5973142A (en) * 1997-01-21 1999-10-26 Yasuda; Nobuyoshi Process for synthesizing carbapenem intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218459A (en) * 1977-12-28 1980-08-19 Merck & Co., Inc. 6-Amido-1-carba-2-penem-3-carboxylic acid
US4203902A (en) * 1978-04-21 1980-05-20 Merck & Co., Inc. Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
US4267188A (en) * 1979-08-09 1981-05-12 Merck & Co., Inc. 5-Substituted-1-carba-pen-2-em-3-carboxylic acid
US4262009A (en) * 1979-12-03 1981-04-14 Merck & Co., Inc. 6- And 1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acid

Also Published As

Publication number Publication date
DK93481A (da) 1981-09-04
AU6795681A (en) 1981-09-10
GB2071656B (en) 1984-02-15
BE887752A (fr) 1981-09-02
FR2477147A1 (en:Method) 1981-09-04
PL229973A1 (en:Method) 1981-10-30
US4377591A (en) 1983-03-22
ES8205225A1 (es) 1982-06-01
SE8101323L (sv) 1981-09-04
ES500032A0 (es) 1982-06-01
JPS56122379A (en) 1981-09-25
DD156911A5 (de) 1982-09-29
DE3107854A1 (de) 1982-02-25
NL8101039A (nl) 1981-10-01
IT8167300A0 (it) 1981-03-03
FR2477147B1 (en:Method) 1983-11-25
GB2071656A (en) 1981-09-23
JPS6237630B2 (en:Method) 1987-08-13

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