IL64859A - 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL64859A
IL64859A IL64859A IL6485982A IL64859A IL 64859 A IL64859 A IL 64859A IL 64859 A IL64859 A IL 64859A IL 6485982 A IL6485982 A IL 6485982A IL 64859 A IL64859 A IL 64859A
Authority
IL
Israel
Prior art keywords
azabicyclo
hept
ene
oxo
preparation
Prior art date
Application number
IL64859A
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH62081A external-priority patent/CH646171A5/en
Priority claimed from CH7802/81A external-priority patent/CH651564A5/en
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL64859A publication Critical patent/IL64859A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL64859A 1981-01-30 1982-01-25 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them IL64859A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH62081A CH646171A5 (en) 1981-01-30 1981-01-30 Bicyclic compounds
CH7802/81A CH651564A5 (en) 1981-12-07 1981-12-07 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
IL64859A true IL64859A (en) 1985-06-30

Family

ID=25685143

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64859A IL64859A (en) 1981-01-30 1982-01-25 7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (15)

Country Link
AT (1) AT377762B (en)
AU (1) AU7979882A (en)
CA (1) CA1179675A (en)
DE (1) DE3201957A1 (en)
DK (1) DK32082A (en)
FR (1) FR2499081B1 (en)
GB (1) GB2092147B (en)
IE (1) IE52421B1 (en)
IL (1) IL64859A (en)
IT (1) IT1153416B (en)
LU (1) LU83906A1 (en)
NL (1) NL8200217A (en)
NZ (1) NZ199487A (en)
PH (1) PH19227A (en)
SE (1) SE8200515L (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725594A (en) * 1984-12-13 1988-02-16 Merck & Co., Inc. Carbapenems having an internally or externally alkylated mono- or bicyclic 2-quaternary heteroarylalxyl heteromethyl substituent
US4680292A (en) * 1984-12-13 1987-07-14 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent
US4729993A (en) * 1984-12-13 1988-03-08 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl substituent
GB8607921D0 (en) * 1986-04-01 1986-05-08 Fujisawa Pharmaceutical Co 3,4-disubstituted-2-azetidinone derivatives
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
US5068232A (en) * 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5607928A (en) * 1994-08-05 1997-03-04 Zeneca Limited Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives
US7632828B2 (en) * 2004-06-10 2009-12-15 Fob Synthesis, Inc. Gram-positive carbapenem antibacterials and processes for their preparation
US20110118462A1 (en) * 2009-11-18 2011-05-19 Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory N-heterocyclic substituent-containing antibiotic, preparation and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DE2811514A1 (en) * 1977-03-19 1978-09-21 Beecham Group Ltd ESTER OF 7-OXO-1-AZABICYCLO SQUARE CLAMP ON 3.2.0 SQUARE CLAMP FOR HEPT-2-EN-2-CARBONIC ACID AND ITS DERIVATIVES, METHOD FOR PRODUCING THESE COMPOUNDS AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
GB2021656B (en) * 1978-05-11 1982-08-25 Ladd Harley G F Pleat forming means and method
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
JPS56122379A (en) * 1980-03-03 1981-09-25 Sankyo Co Ltd 1-carba-2-penem-3-carboxylic acid derivative

Also Published As

Publication number Publication date
DK32082A (en) 1982-07-31
AT377762B (en) 1985-04-25
DE3201957A1 (en) 1982-09-09
IE820197L (en) 1982-07-30
ATA34082A (en) 1984-09-15
CA1179675A (en) 1984-12-18
SE8200515L (en) 1982-07-31
NL8200217A (en) 1982-08-16
IE52421B1 (en) 1987-10-28
LU83906A1 (en) 1983-09-02
FR2499081B1 (en) 1985-07-26
GB2092147A (en) 1982-08-11
GB2092147B (en) 1984-12-05
IT8219187A0 (en) 1982-01-19
FR2499081A1 (en) 1982-08-06
AU7979882A (en) 1982-09-23
IT1153416B (en) 1987-01-14
PH19227A (en) 1986-02-12
NZ199487A (en) 1986-02-21

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