ZA807864B - 3-acylamino-5-(pyridinyl)-2(1h)-pyridinones and preparation thereof - Google Patents

3-acylamino-5-(pyridinyl)-2(1h)-pyridinones and preparation thereof

Info

Publication number
ZA807864B
ZA807864B ZA00807864A ZA807864A ZA807864B ZA 807864 B ZA807864 B ZA 807864B ZA 00807864 A ZA00807864 A ZA 00807864A ZA 807864 A ZA807864 A ZA 807864A ZA 807864 B ZA807864 B ZA 807864B
Authority
ZA
South Africa
Prior art keywords
pyridinones
acylamino
pyridinyl
preparation
Prior art date
Application number
ZA00807864A
Other languages
English (en)
Inventor
G Lesher
C Opalka Jr
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ZA807864B publication Critical patent/ZA807864B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA00807864A 1979-12-26 1980-12-17 3-acylamino-5-(pyridinyl)-2(1h)-pyridinones and preparation thereof ZA807864B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/106,764 US4271168A (en) 1979-12-26 1979-12-26 Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones

Publications (1)

Publication Number Publication Date
ZA807864B true ZA807864B (en) 1981-12-30

Family

ID=22313122

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00807864A ZA807864B (en) 1979-12-26 1980-12-17 3-acylamino-5-(pyridinyl)-2(1h)-pyridinones and preparation thereof

Country Status (25)

Country Link
US (1) US4271168A (sv)
JP (1) JPS56103164A (sv)
KR (1) KR830004291A (sv)
AR (1) AR230435A1 (sv)
AT (1) AT373876B (sv)
AU (1) AU6556680A (sv)
BE (1) BE886766A (sv)
CA (1) CA1131231A (sv)
DE (1) DE3048635A1 (sv)
DK (1) DK550480A (sv)
ES (1) ES498144A0 (sv)
FI (1) FI803973L (sv)
FR (1) FR2472563A1 (sv)
GB (1) GB2066251B (sv)
IE (1) IE50523B1 (sv)
IL (1) IL61690A (sv)
IT (1) IT1134860B (sv)
LU (1) LU83032A1 (sv)
NL (1) NL8006824A (sv)
NO (1) NO803911L (sv)
NZ (1) NZ195878A (sv)
PH (1) PH15974A (sv)
PT (1) PT72264B (sv)
SE (1) SE8009134L (sv)
ZA (1) ZA807864B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587411A (ja) * 1981-07-07 1983-01-17 Mitsui Toatsu Chem Inc 薄肉射出成形用プロピレン/エチレン共重合体の製造方法
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
BE896678A (fr) * 1982-05-18 1983-11-07 Sandoz Sa Nouveaux derives de la 2 (1h)-pyridinone, leur preparation et leur utilisation comme medicaments.
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
RU2423351C2 (ru) 2004-12-16 2011-07-10 Вертекс Фармасьютикалз Инкорпорейтед Пирид-2-оны, применимые как ингибиторы протеинкиназ семейства тес для лечения воспалительных, пролиферативных и иммунологически-опосредованных заболеваний

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
GB2066251A (en) 1981-07-08
IE802619L (en) 1981-06-26
IT8026876A0 (it) 1980-12-22
DK550480A (da) 1981-06-27
NZ195878A (en) 1982-11-23
ES8201136A1 (es) 1981-12-01
AU6556680A (en) 1981-07-02
KR830004291A (ko) 1983-07-09
PH15974A (en) 1983-05-11
NO803911L (no) 1981-06-29
PT72264A (en) 1981-01-01
IE50523B1 (en) 1986-04-30
IT1134860B (it) 1986-08-20
SE8009134L (sv) 1981-06-27
ES498144A0 (es) 1981-12-01
PT72264B (en) 1981-11-05
AR230435A1 (es) 1984-04-30
JPS56103164A (en) 1981-08-18
FR2472563A1 (fr) 1981-07-03
ATA629380A (de) 1983-07-15
FI803973L (fi) 1981-06-27
GB2066251B (en) 1983-10-19
DE3048635A1 (de) 1981-09-17
US4271168A (en) 1981-06-02
IL61690A (en) 1983-11-30
CA1131231A (en) 1982-09-07
IL61690A0 (en) 1981-01-30
BE886766A (fr) 1981-06-19
LU83032A1 (fr) 1981-07-23
AT373876B (de) 1984-02-27
NL8006824A (nl) 1981-07-16

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