ZA805374B - 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives - Google Patents

5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives

Info

Publication number
ZA805374B
ZA805374B ZA00805374A ZA805374A ZA805374B ZA 805374 B ZA805374 B ZA 805374B ZA 00805374 A ZA00805374 A ZA 00805374A ZA 805374 A ZA805374 A ZA 805374A ZA 805374 B ZA805374 B ZA 805374B
Authority
ZA
South Africa
Prior art keywords
trinor
inter
phenylene pgi2
pgi2 derivatives
derivatives
Prior art date
Application number
ZA00805374A
Other languages
English (en)
Inventor
Kiyotaka Ohno
Ohno Kiyotaka
Hisao Nishiyama
Nishiyama Hisao
Shintaro Nishio
Nishio Shintaro
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of ZA805374B publication Critical patent/ZA805374B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
ZA00805374A 1979-09-03 1980-08-29 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives ZA805374B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54111709A JPS5931510B2 (ja) 1979-09-03 1979-09-03 ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体

Publications (1)

Publication Number Publication Date
ZA805374B true ZA805374B (en) 1982-08-25

Family

ID=14568162

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00805374A ZA805374B (en) 1979-09-03 1980-08-29 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives

Country Status (7)

Country Link
US (1) US4301164A (xx)
EP (1) EP0024943B1 (xx)
JP (1) JPS5931510B2 (xx)
AU (1) AU534925B2 (xx)
DE (1) DE3064582D1 (xx)
DK (1) DK372380A (xx)
ZA (1) ZA805374B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57144276A (en) * 1981-03-03 1982-09-06 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
JPS58124778A (ja) * 1982-01-20 1983-07-25 Toray Ind Inc ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体
US4401824A (en) * 1982-03-08 1983-08-30 The Upjohn Company Benzopyran compounds, derivatives of prostaglandins
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
US4561604A (en) * 1983-07-18 1985-12-31 Shimano Industrial Company Limited Spinning reel
US4739078A (en) * 1984-02-17 1988-04-19 The Upjohn Company Use of borohydride-salt lanthanide salt reagents for stereo selective reduction of C-15-keto prostaglandin precursors
US4668814A (en) * 1984-03-08 1987-05-26 The Upjohn Company Interphenylene carbacyclin derivatives
CA1241324A (en) 1984-03-08 1988-08-30 Paul A. Aristoff Interphenylene carbacyclin derivatives
US4683330A (en) * 1984-03-08 1987-07-28 The Upjohn Company Interphenylene carbacyclin derivatives
DE3574470D1 (en) * 1985-09-18 1990-01-04 Upjohn Co Stereoselective reduktion.
US4775692A (en) * 1986-01-24 1988-10-04 Toray Industries, Inc. 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
US5008250A (en) * 1988-05-25 1991-04-16 Merck & Co., Inc. Avermectins with a cleaved furan ring and an 8a hydroxy group
US5233059A (en) * 1991-07-25 1993-08-03 Iowa State University Research Foundation, Inc. Synthesis of benzoprostacyclins using palladium catalysis
US5169959A (en) * 1991-09-23 1992-12-08 Iowa State University Research Foundation, Inc. Free radical-catalyzed synthesis of benzoprostacyclins
WO1998037895A1 (fr) * 1997-02-27 1998-09-03 Toray Industries, Inc. Medicaments permettant d'ameliorer la circulation pulmonaire
CA2303343C (en) * 1997-09-16 2011-01-04 Toray Industries, Inc. C-c chemokine production inhibitor
SE9803107D0 (sv) * 1998-09-14 1998-09-14 Astra Pharma Prod Novel Compunds
CN1377263A (zh) * 1999-08-05 2002-10-30 帝人株式会社 含有含氮化合物作为活性成分的神经损伤治疗剂
HU227157B1 (en) * 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation
GB0215757D0 (en) * 2002-07-08 2002-08-14 Cascade Biochem Ltd Benzoprostacyclin intermediates methods for their preparation and products derived therefrom

Also Published As

Publication number Publication date
EP0024943B1 (en) 1983-08-17
DK372380A (da) 1981-03-04
AU6184180A (en) 1981-03-12
JPS5636477A (en) 1981-04-09
DE3064582D1 (en) 1983-09-22
AU534925B2 (en) 1984-02-23
JPS5931510B2 (ja) 1984-08-02
US4301164A (en) 1981-11-17
EP0024943A1 (en) 1981-03-11

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