DE3064582D1 - 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives and pharmaceutical compositions containing them - Google Patents

5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives and pharmaceutical compositions containing them

Info

Publication number
DE3064582D1
DE3064582D1 DE8080303046T DE3064582T DE3064582D1 DE 3064582 D1 DE3064582 D1 DE 3064582D1 DE 8080303046 T DE8080303046 T DE 8080303046T DE 3064582 T DE3064582 T DE 3064582T DE 3064582 D1 DE3064582 D1 DE 3064582D1
Authority
DE
Germany
Prior art keywords
trinor
inter
pharmaceutical compositions
compositions containing
phenylene pgi2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080303046T
Other languages
English (en)
Inventor
Kiyotaka Ohno
Hisao Nishiyama
Shintaro Nishio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of DE3064582D1 publication Critical patent/DE3064582D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
DE8080303046T 1979-09-03 1980-09-02 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives and pharmaceutical compositions containing them Expired DE3064582D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54111709A JPS5931510B2 (ja) 1979-09-03 1979-09-03 ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体

Publications (1)

Publication Number Publication Date
DE3064582D1 true DE3064582D1 (en) 1983-09-22

Family

ID=14568162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080303046T Expired DE3064582D1 (en) 1979-09-03 1980-09-02 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivatives and pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US4301164A (de)
EP (1) EP0024943B1 (de)
JP (1) JPS5931510B2 (de)
AU (1) AU534925B2 (de)
DE (1) DE3064582D1 (de)
DK (1) DK372380A (de)
ZA (1) ZA805374B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57144276A (en) * 1981-03-03 1982-09-06 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
JPS58124778A (ja) * 1982-01-20 1983-07-25 Toray Ind Inc ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体
US4401824A (en) * 1982-03-08 1983-08-30 The Upjohn Company Benzopyran compounds, derivatives of prostaglandins
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
US4561604A (en) * 1983-07-18 1985-12-31 Shimano Industrial Company Limited Spinning reel
US4739078A (en) * 1984-02-17 1988-04-19 The Upjohn Company Use of borohydride-salt lanthanide salt reagents for stereo selective reduction of C-15-keto prostaglandin precursors
CA1241324A (en) 1984-03-08 1988-08-30 Paul A. Aristoff Interphenylene carbacyclin derivatives
US4668814A (en) * 1984-03-08 1987-05-26 The Upjohn Company Interphenylene carbacyclin derivatives
US4683330A (en) * 1984-03-08 1987-07-28 The Upjohn Company Interphenylene carbacyclin derivatives
EP0219580B1 (de) * 1985-09-18 1989-11-29 The Upjohn Company Stereoselective Reduktion
US4775692A (en) * 1986-01-24 1988-10-04 Toray Industries, Inc. 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
US5008250A (en) * 1988-05-25 1991-04-16 Merck & Co., Inc. Avermectins with a cleaved furan ring and an 8a hydroxy group
US5233059A (en) * 1991-07-25 1993-08-03 Iowa State University Research Foundation, Inc. Synthesis of benzoprostacyclins using palladium catalysis
US5169959A (en) * 1991-09-23 1992-12-08 Iowa State University Research Foundation, Inc. Free radical-catalyzed synthesis of benzoprostacyclins
WO1998037895A1 (fr) * 1997-02-27 1998-09-03 Toray Industries, Inc. Medicaments permettant d'ameliorer la circulation pulmonaire
EP1016408B1 (de) * 1997-09-16 2006-04-19 Toray Industries, Inc. Neue pharnazeutische verwendung von c-c chemokin produktionsinhibitoren
SE9803107D0 (sv) * 1998-09-14 1998-09-14 Astra Pharma Prod Novel Compunds
CA2382759A1 (en) * 1999-08-05 2001-02-15 Teijin Limited Agent for the remedy of neural damage having a nitrogen-containing compound as the active ingredient
HU227157B1 (en) 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation
GB0215757D0 (en) * 2002-07-08 2002-08-14 Cascade Biochem Ltd Benzoprostacyclin intermediates methods for their preparation and products derived therefrom

Also Published As

Publication number Publication date
JPS5636477A (en) 1981-04-09
DK372380A (da) 1981-03-04
EP0024943A1 (de) 1981-03-11
AU6184180A (en) 1981-03-12
JPS5931510B2 (ja) 1984-08-02
EP0024943B1 (de) 1983-08-17
ZA805374B (en) 1982-08-25
US4301164A (en) 1981-11-17
AU534925B2 (en) 1984-02-23

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: SCHWABE, H., DIPL.-ING. SANDMAIR, K., DIPL.-CHEM. DR.JUR. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN