ZA803789B - Process for preparing new derivatives of tetrahydropyridinyl indoles and their salts - Google Patents

Process for preparing new derivatives of tetrahydropyridinyl indoles and their salts

Info

Publication number
ZA803789B
ZA803789B ZA00803789A ZA803789A ZA803789B ZA 803789 B ZA803789 B ZA 803789B ZA 00803789 A ZA00803789 A ZA 00803789A ZA 803789 A ZA803789 A ZA 803789A ZA 803789 B ZA803789 B ZA 803789B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
indoles
hydrogen
alkyl
salts
Prior art date
Application number
ZA00803789A
Other languages
English (en)
Inventor
L Nedelec
J Guillaume
C Dumont
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA803789B publication Critical patent/ZA803789B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
ZA00803789A 1979-07-13 1980-06-25 Process for preparing new derivatives of tetrahydropyridinyl indoles and their salts ZA803789B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7918217A FR2460947A1 (fr) 1979-07-13 1979-07-13 Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Publications (1)

Publication Number Publication Date
ZA803789B true ZA803789B (en) 1981-06-24

Family

ID=9227845

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA00803793A ZA803793B (en) 1979-07-13 1980-06-25 Derivatives of tetrahydropyrid-4-yl-indole and their salts, their preparation, their ise as medicaments and the compositions containing them
ZA00803789A ZA803789B (en) 1979-07-13 1980-06-25 Process for preparing new derivatives of tetrahydropyridinyl indoles and their salts

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA00803793A ZA803793B (en) 1979-07-13 1980-06-25 Derivatives of tetrahydropyrid-4-yl-indole and their salts, their preparation, their ise as medicaments and the compositions containing them

Country Status (16)

Country Link
US (1) US4324790A (de)
EP (1) EP0022705B1 (de)
JP (2) JPS5615283A (de)
AT (1) ATE2954T1 (de)
AU (1) AU535197B2 (de)
BE (1) BE884279A (de)
CA (1) CA1145752A (de)
DE (1) DE3062614D1 (de)
DK (1) DK152048C (de)
ES (2) ES493311A0 (de)
FR (1) FR2460947A1 (de)
HU (1) HU184792B (de)
IE (1) IE50067B1 (de)
PT (1) PT71549B (de)
SU (1) SU936813A3 (de)
ZA (2) ZA803793B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
US5214059A (en) * 1989-07-03 1993-05-25 Hoechst-Roussel Pharmaceuticals Incorporated 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
PL1883451T3 (pl) * 2005-04-13 2011-05-31 Neuraxon Inc Podstawione związki indolowe mające aktywność hamowania NOS
ZA200809659B (en) * 2006-04-13 2010-03-31 Neuraxon Inc 1,5 and 3,6-substituted indole compounds having NOS inhibitory activity
CA2705422A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
WO2009062318A1 (en) * 2007-11-16 2009-05-22 Neuraxon, Inc. 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity
MX356032B (es) * 2007-11-16 2018-04-11 Neuraxon Inc Compuestos indola y métodos para tratar el dolor visceral.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2193584B1 (de) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
SU639243A1 (ru) * 1976-12-27 1979-11-25 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср 1-/4-(4-Фторфенил)-4-оксибутил/ -4- (индолил-31)-1,2,3,6-тетрагидропиридин или его соли, обладающие психотропными свойствами
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels

Also Published As

Publication number Publication date
US4324790A (en) 1982-04-13
ES8107213A1 (es) 1981-08-16
DK152048B (da) 1988-01-25
DK300180A (da) 1981-01-14
JPS5615282A (en) 1981-02-14
IE801456L (en) 1981-01-13
HU184792B (en) 1984-10-29
JPS5615283A (en) 1981-02-14
AU6035980A (en) 1981-01-15
EP0022705A1 (de) 1981-01-21
FR2460947B1 (de) 1981-07-10
ES8107214A1 (es) 1981-08-16
ZA803793B (en) 1981-06-24
AU535197B2 (en) 1984-03-08
FR2460947A1 (fr) 1981-01-30
DK152048C (da) 1988-10-10
IE50067B1 (en) 1986-02-05
JPS6351154B2 (de) 1988-10-13
ATE2954T1 (de) 1983-04-15
BE884279A (fr) 1981-01-12
CA1145752A (fr) 1983-05-03
ES493311A0 (es) 1981-08-16
PT71549B (fr) 1981-12-14
SU936813A3 (ru) 1982-06-15
EP0022705B1 (de) 1983-04-06
DE3062614D1 (en) 1983-05-11
ES493308A0 (es) 1981-08-16
JPS6348872B2 (de) 1988-09-30
PT71549A (fr) 1980-08-01

Similar Documents

Publication Publication Date Title
ES476786A1 (es) Procedimiento para preparar nuevos derivados de tetrahidro- piridinilindol.
ES8106721A1 (es) Un metodo para la preparacion de derivados de ftalimidina
ES8700851A1 (es) Procedimiento para la obtencion de acido alquil-1- ciclopropil-1, 4-dihidro-4-oxo-3-quinolincarboxilico.
ZA803789B (en) Process for preparing new derivatives of tetrahydropyridinyl indoles and their salts
IE801615L (en) 4-phenoxypiperidine derivatives.
DE3060932D1 (en) Indole derivatives, their preparation and their use for medicaments
IL67812A (en) Indanylbenzamide derivatives,process for the preparation thereof and fungicidal compositions comprising the same
DE3274860D1 (en) Triazoloquinazolones and their salts, process and intermediates for preparing them, their use as medicines and compositions containing them
DK84380A (da) Phenylpiperazinderivater fremgangsmaade til deres fremstilling og deres anvendelse
ES524990A0 (es) Procedimiento para preparar derivados de tieno-tiazol
ES8103081A1 (es) Procedimiento para la obtencion de diazatriciclos
IE801457L (en) Tetrahydropyridyl indoles
DE3375300D1 (en) 9-oxalysergic-acid derivatives, their salts, process and intermediates for their preparation, their use as pharmaceutical preparations and compositions containing them
JPS56154431A (en) Substituted 3-aryl-2-cycloalkene-1-one and its manufacture
DE3874920D1 (de) Benzimidazol-2-one-derivate, deren salze, verfahren und zwischenprodukte zu deren herstellung, deren anwendung als arzneimittel und sie enthaltende zusammensetzungen.
HU894471D0 (en) Process for the preparation of 15-amino-20,21-dinor-eburnamenine derivatives and pharmaceutical compositions containing them
ES500108A0 (es) Procedimiento para preparar nuevas benzotiopirano (2,3-c)pi-ridinas
ES8307798A1 (es) Un procedimiento para la preparacion de derivados de piperazilmetil-4-dibenzofuranona, o, dibenzofuranol.
ZA838139B (en) Semicarbazides,process for preparing these,and pharmaceutical compositions thereof