ZA802011B - New prostaglandin derivatives in the 6-keto-pge1 series - Google Patents
New prostaglandin derivatives in the 6-keto-pge1 seriesInfo
- Publication number
- ZA802011B ZA802011B ZA00802011A ZA802011A ZA802011B ZA 802011 B ZA802011 B ZA 802011B ZA 00802011 A ZA00802011 A ZA 00802011A ZA 802011 A ZA802011 A ZA 802011A ZA 802011 B ZA802011 B ZA 802011B
- Authority
- ZA
- South Africa
- Prior art keywords
- keto
- prostaglandin derivatives
- new prostaglandin
- pge1 series
- pge1
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- ROUDCKODIMKLNO-CTBSXBMHSA-N 6-oxoprostaglandin E1 Chemical class CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CC(=O)CCCCC(O)=O ROUDCKODIMKLNO-CTBSXBMHSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792913856 DE2913856A1 (de) | 1979-04-06 | 1979-04-06 | Neue prostaglandinderivate in der 6-keto-pge tief 1 -reihe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA802011B true ZA802011B (en) | 1981-04-29 |
Family
ID=6067601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00802011A ZA802011B (en) | 1979-04-06 | 1980-04-03 | New prostaglandin derivatives in the 6-keto-pge1 series |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4304783A (fr) |
| EP (1) | EP0019069B1 (fr) |
| JP (1) | JPS55141465A (fr) |
| AT (1) | ATE8621T1 (fr) |
| AU (1) | AU544615B2 (fr) |
| CA (1) | CA1152505A (fr) |
| DE (2) | DE2913856A1 (fr) |
| ES (1) | ES8202539A1 (fr) |
| HU (1) | HU184735B (fr) |
| IL (1) | IL59768A (fr) |
| ZA (1) | ZA802011B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3401542A1 (de) * | 1984-01-18 | 1985-08-01 | Merck Patent Gmbh, 6100 Darmstadt | Schwefelhaltige 6-ketoprostaglandine |
| JPS60181068A (ja) * | 1984-02-29 | 1985-09-14 | Teijin Ltd | ６−置換プロスタグランジンｅ↓１類およびその製造法 |
| DE3708537A1 (de) * | 1987-03-13 | 1988-09-22 | Schering Ag | 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
| US4791133A (en) * | 1987-06-26 | 1988-12-13 | G. D. Searle & Co. | Phenylene, furyl, and thienyl leukotriene B4 analogues |
| US5834498A (en) * | 1992-09-21 | 1998-11-10 | Allergan | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| US6576663B2 (en) | 1999-12-22 | 2003-06-10 | Alcon, Inc. | 6-Keto prostaglandin F1α and analogs for treating dry eye |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
| US4205178A (en) * | 1976-12-30 | 1980-05-27 | The Upjohn Company | 6-Keto prostaglandin E-type compounds |
| JPS6022710B2 (ja) * | 1977-09-16 | 1985-06-03 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
-
1979
- 1979-04-06 DE DE19792913856 patent/DE2913856A1/de not_active Withdrawn
-
1980
- 1980-03-28 ES ES490031A patent/ES8202539A1/es not_active Expired
- 1980-04-01 AT AT80101719T patent/ATE8621T1/de not_active IP Right Cessation
- 1980-04-01 EP EP80101719A patent/EP0019069B1/fr not_active Expired
- 1980-04-01 DE DE8080101719T patent/DE3068652D1/de not_active Expired
- 1980-04-03 ZA ZA00802011A patent/ZA802011B/xx unknown
- 1980-04-03 US US06/136,819 patent/US4304783A/en not_active Expired - Lifetime
- 1980-04-03 AU AU57170/80A patent/AU544615B2/en not_active Ceased
- 1980-04-03 CA CA000349229A patent/CA1152505A/fr not_active Expired
- 1980-04-03 HU HU80808A patent/HU184735B/hu not_active IP Right Cessation
- 1980-04-04 IL IL59768A patent/IL59768A/xx unknown
- 1980-04-05 JP JP4408380A patent/JPS55141465A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU544615B2 (en) | 1985-06-06 |
| EP0019069A2 (fr) | 1980-11-26 |
| HU184735B (en) | 1984-10-29 |
| DE2913856A1 (de) | 1980-10-23 |
| IL59768A0 (en) | 1980-06-30 |
| JPS55141465A (en) | 1980-11-05 |
| ATE8621T1 (de) | 1984-08-15 |
| AU5717080A (en) | 1980-10-09 |
| CA1152505A (fr) | 1983-08-23 |
| DE3068652D1 (en) | 1984-08-30 |
| IL59768A (en) | 1986-01-31 |
| ES490031A0 (es) | 1982-02-01 |
| ES8202539A1 (es) | 1982-02-01 |
| EP0019069B1 (fr) | 1984-07-25 |
| EP0019069A3 (en) | 1981-01-14 |
| US4304783A (en) | 1981-12-08 |
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