ZA796244B - New derivatives of 3-quinoline-carboxylic acid,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them - Google Patents

New derivatives of 3-quinoline-carboxylic acid,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them

Info

Publication number
ZA796244B
ZA796244B ZA00796244A ZA796244A ZA796244B ZA 796244 B ZA796244 B ZA 796244B ZA 00796244 A ZA00796244 A ZA 00796244A ZA 796244 A ZA796244 A ZA 796244A ZA 796244 B ZA796244 B ZA 796244B
Authority
ZA
South Africa
Prior art keywords
quinoline
medicament
preparing
carboxylic acid
pharmaceutical compositions
Prior art date
Application number
ZA00796244A
Other languages
English (en)
Inventor
R Deraedt
F Clemence
O Martret
A Allais
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA796244B publication Critical patent/ZA796244B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA00796244A 1978-12-08 1979-11-19 New derivatives of 3-quinoline-carboxylic acid,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them ZA796244B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7834592A FR2443467A1 (fr) 1978-12-08 1978-12-08 Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number Publication Date
ZA796244B true ZA796244B (en) 1980-11-26

Family

ID=9215841

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00796244A ZA796244B (en) 1978-12-08 1979-11-19 New derivatives of 3-quinoline-carboxylic acid,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US4299831A (de)
EP (2) EP0049555B1 (de)
JP (1) JPS5581878A (de)
AU (1) AU531501B2 (de)
CA (1) CA1137985A (de)
DE (1) DE2966142D1 (de)
DK (1) DK149773C (de)
ES (1) ES8103045A1 (de)
FR (1) FR2443467A1 (de)
HU (1) HU182570B (de)
IE (1) IE49875B1 (de)
ZA (1) ZA796244B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482596A1 (fr) * 1980-05-19 1981-11-20 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament
HU190796B (en) * 1981-06-12 1986-11-28 Roussel Uclaf,Fr Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
FR2509728A1 (fr) * 1981-07-17 1983-01-21 Roussel Uclaf Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2537139B2 (fr) * 1982-03-15 1985-09-20 Roussel Uclaf Nouveau derive de la n-dihydrothiazolyl 3-quinoleine carboxamide, procede de preparation, application a titre de medicament et compositions le renfermant
FR2532314B1 (fr) * 1982-08-25 1985-07-19 Roussel Uclaf Nouveau procede de preparation de derives de l'acide 3-quinoleine carboxylique, nouveaux derives halogenes de l'acide 3-quinoleine carboxylique, leur application comme medicaments, les compositions pharmaceutiques les renfermant et les intermediaires nouveaux obtenus
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
FR2612189B1 (fr) * 1987-03-13 1989-06-23 Roussel Uclaf Nouveaux derives de la pyridine, leur procede de preparation et les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions les renfermant
FR2636329B2 (fr) * 1987-03-13 1990-11-02 Roussel Uclaf Nouveaux derives de la pyridine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant
US4966906A (en) * 1987-11-27 1990-10-30 Hoechst-Roussel Pharmaceuticals Inc. 1-aryl-3-isoquinolinecarboxamides
US5028707A (en) * 1989-11-20 1991-07-02 Board Of Regents, University Of Texas 4-hydroxyquinaldic acid derivatives
GB9108547D0 (en) * 1991-04-22 1991-06-05 Fujisawa Pharmaceutical Co Quinoline derivatives
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
WO2005035484A1 (ja) * 2003-10-10 2005-04-21 Toyo Kasei Kogyo Company Limited １－アリール－５－（トリフルオロメチル）－１ｈ－テトラゾールの製造方法
MX341797B (es) * 2004-06-24 2016-09-02 Vertex Pharmaceuticals Incorporated * Moduladores de transportadores con casete de union con atp.
US20110064811A1 (en) 2005-12-28 2011-03-17 Patricia Hurter Solid forms of N-[2,4-BIS(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
MX2011009867A (es) 2009-03-20 2012-01-12 Vertex Pharma Proceso para producir moduladores del regulador de conductancia transmembrana de fibrosis quistica.
CN109966264A (zh) 2012-02-27 2019-07-05 沃泰克斯药物股份有限公司 药物组合物及其施用
EP3204358B1 (de) 2014-10-07 2018-09-19 Vertex Pharmaceuticals Incorporated Cokristalle von modulatoren des transmembrankonduktanzregulators bei zystischer fibrose

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044138A (en) * 1972-10-21 1977-08-23 John Wyeth & Brother Limited Pharmaceutical compositions containing 5,6,7,8-tetrahydroquinoline derivatives and related compounds
FR2281761A1 (fr) * 1974-08-13 1976-03-12 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2324304A2 (fr) * 1975-09-22 1977-04-15 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
JPS5291876A (en) * 1976-01-27 1977-08-02 Roussel Uclaf Novel derivatives of 33quinolinecarboxylic acid and medicine comprising same
FR2340735A1 (fr) * 1976-02-11 1977-09-09 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DK520679A (da) 1980-06-09
EP0049555B1 (de) 1984-02-22
EP0012639B1 (de) 1983-09-07
DK149773C (da) 1987-03-23
JPS5581878A (en) 1980-06-20
IE792367L (en) 1980-06-08
ES486671A0 (es) 1981-02-16
IE49875B1 (en) 1986-01-08
HU182570B (en) 1984-02-28
DE2966142D1 (en) 1983-10-13
AU5358579A (en) 1980-06-12
EP0049555A1 (de) 1982-04-14
AU531501B2 (en) 1983-08-25
FR2443467B1 (de) 1981-08-14
EP0012639A3 (en) 1980-11-12
FR2443467A1 (fr) 1980-07-04
ES8103045A1 (es) 1981-02-16
CA1137985A (fr) 1982-12-21
JPS6330914B2 (de) 1988-06-21
US4299831A (en) 1981-11-10
DK149773B (da) 1986-09-29
EP0012639A2 (de) 1980-06-25

Similar Documents

Publication Publication Date Title
IL56734A0 (en) Phemoxyalkylcarboxylic acid derivatives,process for their preparation and pharmaceutical compositions containing thesame
DE2966476D1 (en) Azabicycloalkyl derivatives, a process for their preparation and pharmaceutical compositions containing them
CS420091A3 (en) Derivatives of carbazol-4-yloxy-propanol amine, process of their preparation and medicament containing these compounds
DE2861318D1 (en) New derivatives of 4-phenyl-2-(2',2',2-trichlorethoxycarboxamido)-thiazole useful as medicaments, pharmaceutical compositions containing them and process for the preparation of these compounds
ZA796244B (en) New derivatives of 3-quinoline-carboxylic acid,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them
DE2960178D1 (en) New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2965279D1 (en) Indanyl derivatives, process for their preparation and pharmaceutical compositions containing these compounds
DE2961571D1 (en) Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them
PT69821A (en) Process for the preparation of new 5-phenylpyrazole derivatives the salts thereof and the pharmaceutical compositions containing same
ZA794267B (en) New derivatives of 3-(aminoethyl)phenol and their salts,a process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
DE2964209D1 (en) Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
IL57785A0 (en) New imidazoquinoxalines and their salts,process for their preparation,their use as medicaments and the pharmaceutical compositions containing them
DE2962112D1 (en) Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them
IL56421A0 (en) 4-pyridone-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
DE2966364D1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them
ZA793100B (en) New acetylene derivatives of androst-4-ene,process for preparing them,their use as a medicament and the pharmaceutical compositions containing them
ZA796386B (en) New process for preparing derivatives of piperidyl-indole,new compound obtained and its salts,their use as medicaments and the pharmaceutical compositions containing them
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
ZA793967B (en) New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
DE2962169D1 (en) Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents
ZA786369B (en) New derivatives of 5h-benzocyclohepten-7-amine and their salts,process for preparing them and the pharmaceutical compositions containing them
IL56461A (en) 1-naphthyl-acetic acid derivatives,their preparation and pharmaceutical compositions containing them
IL59857A0 (en) New derivatives of 1 ,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it
IL57735A (en) 7beta-aminothiazolyl-acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
DE2962886D1 (en) Derivatives of l-cysteine, their use as medicaments and process for their preparation