ZA785394B - A novel process for producing 7-(d(-)-a-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)a-(4-hydroxophenyl)acetamido/-3-/5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl/-delta3-cephem-4-carboxylic acid and a pharmaceutically acceptable salt thereof and an intermediate thereof and a process for producing the intermediate - Google Patents

A novel process for producing 7-(d(-)-a-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)a-(4-hydroxophenyl)acetamido/-3-/5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl/-delta3-cephem-4-carboxylic acid and a pharmaceutically acceptable salt thereof and an intermediate thereof and a process for producing the intermediate

Info

Publication number
ZA785394B
ZA785394B ZA00785394A ZA785394A ZA785394B ZA 785394 B ZA785394 B ZA 785394B ZA 00785394 A ZA00785394 A ZA 00785394A ZA 785394 A ZA785394 A ZA 785394A ZA 785394 B ZA785394 B ZA 785394B
Authority
ZA
South Africa
Prior art keywords
producing
hydroxophenyl
piperazinecarboxamido
delta3
cephem
Prior art date
Application number
ZA00785394A
Other languages
English (en)
Inventor
S Takano
K Momonoi
I Saikawa
K Tanaka
K Hayashi
I Takakura
C Kutani
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ZA785394B publication Critical patent/ZA785394B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00785394A 1977-09-27 1978-09-22 A novel process for producing 7-(d(-)-a-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)a-(4-hydroxophenyl)acetamido/-3-/5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl/-delta3-cephem-4-carboxylic acid and a pharmaceutically acceptable salt thereof and an intermediate thereof and a process for producing the intermediate ZA785394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52115126A JPS6056717B2 (ja) 1977-09-27 1977-09-27 セフアロスポリンのｎ，ｎ−ジメチルアセトアミド付加体及びその製法

Publications (1)

Publication Number Publication Date
ZA785394B true ZA785394B (en) 1979-09-26

Family

ID=14654902

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00785394A ZA785394B (en) 1977-09-27 1978-09-22 A novel process for producing 7-(d(-)-a-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)a-(4-hydroxophenyl)acetamido/-3-/5-(1-methyl-1,2,3,4-tetrazolyl)thiomethyl/-delta3-cephem-4-carboxylic acid and a pharmaceutically acceptable salt thereof and an intermediate thereof and a process for producing the intermediate

Country Status (3)

Country Link
JP (1) JPS6056717B2 (ja)
BE (1) BE870762A (ja)
ZA (1) ZA785394B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3381408D1 (de) * 1982-12-27 1990-05-10 Lilly Co Eli Zwischenverbindungen fuer die herstellung von ceftazidin und verfahren zu ihrer herstellung.

Also Published As

Publication number Publication date
JPS6056717B2 (ja) 1985-12-11
JPS5448784A (en) 1979-04-17
BE870762A (fr) 1979-03-26

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