ZA771381B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA771381B ZA771381B ZA00771381A ZA771381A ZA771381B ZA 771381 B ZA771381 B ZA 771381B ZA 00771381 A ZA00771381 A ZA 00771381A ZA 771381 A ZA771381 A ZA 771381A ZA 771381 B ZA771381 B ZA 771381B
- Authority
- ZA
- South Africa
- Prior art keywords
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/668,872 US4032639A (en) | 1976-03-22 | 1976-03-22 | 2,3,4,4A-Tetrahydro-1H-pyrazino[1,2-a,]quinoxalin-5(6H)-ones and derivatives thereof for relieving hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA771381B true ZA771381B (en) | 1978-10-25 |
Family
ID=24684079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00771381A ZA771381B (en) | 1976-03-22 | 1977-03-08 | Heterocyclic compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4032639A (xx) |
| JP (1) | JPS52114000A (xx) |
| AT (1) | AT357540B (xx) |
| AU (1) | AU506308B2 (xx) |
| BE (1) | BE852737A (xx) |
| CA (1) | CA1093557A (xx) |
| DE (1) | DE2712573A1 (xx) |
| DK (1) | DK122377A (xx) |
| FR (1) | FR2345450A1 (xx) |
| GB (3) | GB1538986A (xx) |
| NL (1) | NL7702920A (xx) |
| SE (1) | SE7703223L (xx) |
| ZA (1) | ZA771381B (xx) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4182872A (en) * | 1976-03-22 | 1980-01-08 | American Home Products Corporation | 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid chemical intermediates |
| US4182869A (en) * | 1976-03-22 | 1980-01-08 | American Home Products Corporation | 4-Carbobenzoxypiperazine-2-carboxylic acid chemical intermediate |
| US4089958A (en) * | 1976-12-20 | 1978-05-16 | American Home Products Corporation | 2,3,4,4A-Tetrahydro-1H-pyrazino[1,2]quinoxalin-5(6)-ones and derivatives thereof |
| US4225713A (en) * | 1977-08-03 | 1980-09-30 | Freed Meier E | Tetrahydro(1H)pyrazino(1,2-A)azaquinoxalin-5(6H)-ones and derivatives thereof |
| US4203987A (en) * | 1979-05-21 | 1980-05-20 | American Home Products Corporation | 3-[Pyridinylalkyl and piperidinylalkyl]-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-ones |
| US6369057B1 (en) | 1991-04-15 | 2002-04-09 | Aventis Pharma Deutschland Gmbh | Quinoxalines, processes for their preparation and their use |
| ATE205837T1 (de) * | 1991-04-15 | 2001-10-15 | Aventis Pharma Gmbh | Chinoxaline, verfahren zu ihrer herstellung und ihre verwendung |
| US5753653A (en) | 1995-12-08 | 1998-05-19 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| TR199800990T2 (xx) * | 1995-12-08 | 1998-07-21 | Agouron Pharmaceuticals, Inc. | Metaloproteinaz inhibit�rleri, bunlar� i�eren farmas�tik bile�imler, bunlar�n farmas�tik kullan�mlar� ve bunlar�n �retiminde kullan�labilecek y�ntemler ve ara �r�nler. |
| US6500948B1 (en) | 1995-12-08 | 2002-12-31 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors-compositions, uses preparation and intermediates thereof |
| US6008243A (en) * | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
| US6174915B1 (en) | 1997-03-25 | 2001-01-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| US5985900A (en) * | 1997-04-01 | 1999-11-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| US6372745B1 (en) * | 1999-12-06 | 2002-04-16 | American Home Products Corporation | 2,3,4,4A-tetrahydro-1H-pyrazino[1,2-A]quinoxalin-5(6H)one derivatives |
| US6476032B2 (en) | 1998-12-17 | 2002-11-05 | Wyeth | 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)one derivatives |
| BR9916326A (pt) * | 1998-12-17 | 2001-10-02 | American Home Prod | Derivados de 2,3,4,4a-tetrahidro-1h-pirazino(1,2-a)quinoxalin-5-(6h) ona sendo agonistas de 5ht2c |
| DE102004058337A1 (de) * | 2004-12-02 | 2006-06-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten |
| US20060211700A1 (en) * | 2005-03-21 | 2006-09-21 | Alcon, Inc. | (R)-8,9-dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one for controlling IOP and treating glaucoma |
| CN104011010B (zh) | 2011-12-14 | 2017-11-28 | 组合化学工业株式会社 | 二苯胺化合物及其制造方法 |
| EP3015451B1 (en) * | 2013-06-25 | 2018-01-17 | Kumiai Chemical Industry Co., Ltd. | Method for producing nitrobenzene compound |
| CN114096533B (zh) * | 2019-09-10 | 2024-03-08 | 四川科伦博泰生物医药股份有限公司 | 一种三并环类化合物，包含其的药物组合物，其制备方法及其用途 |
-
1976
- 1976-03-22 US US05/668,872 patent/US4032639A/en not_active Expired - Lifetime
-
1977
- 1977-03-08 ZA ZA00771381A patent/ZA771381B/xx unknown
- 1977-03-09 AU AU23048/77A patent/AU506308B2/en not_active Expired
- 1977-03-11 CA CA273,768A patent/CA1093557A/en not_active Expired
- 1977-03-17 GB GB11243/77A patent/GB1538986A/en not_active Expired
- 1977-03-17 NL NL7702920A patent/NL7702920A/xx not_active Application Discontinuation
- 1977-03-17 GB GB1313/78A patent/GB1538987A/en not_active Expired
- 1977-03-17 GB GB28412/78A patent/GB1538988A/en not_active Expired
- 1977-03-18 AT AT189377A patent/AT357540B/de not_active IP Right Cessation
- 1977-03-21 FR FR7708408A patent/FR2345450A1/fr active Granted
- 1977-03-21 DK DK122377A patent/DK122377A/da unknown
- 1977-03-21 SE SE7703223A patent/SE7703223L/xx not_active Application Discontinuation
- 1977-03-22 BE BE175997A patent/BE852737A/xx unknown
- 1977-03-22 DE DE19772712573 patent/DE2712573A1/de not_active Withdrawn
- 1977-03-22 JP JP3201577A patent/JPS52114000A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB1538986A (en) | 1979-01-24 |
| SE7703223L (sv) | 1977-09-23 |
| GB1538987A (en) | 1979-01-24 |
| ATA189377A (de) | 1979-12-15 |
| DK122377A (da) | 1977-09-23 |
| US4032639A (en) | 1977-06-28 |
| AU2304877A (en) | 1978-09-14 |
| FR2345450A1 (fr) | 1977-10-21 |
| CA1093557A (en) | 1981-01-13 |
| FR2345450B1 (xx) | 1980-05-09 |
| NL7702920A (nl) | 1977-09-26 |
| BE852737A (fr) | 1977-09-22 |
| AT357540B (de) | 1980-07-10 |
| AU506308B2 (en) | 1979-12-20 |
| DE2712573A1 (de) | 1977-09-29 |
| JPS52114000A (en) | 1977-09-24 |
| GB1538988A (en) | 1979-01-24 |
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