ZA753580B - New 1,4-dihydropyridines and processes for their manufacture - Google Patents

New 1,4-dihydropyridines and processes for their manufacture

Info

Publication number
ZA753580B
ZA753580B ZA00753580A ZA753580A ZA753580B ZA 753580 B ZA753580 B ZA 753580B ZA 00753580 A ZA00753580 A ZA 00753580A ZA 753580 A ZA753580 A ZA 753580A ZA 753580 B ZA753580 B ZA 753580B
Authority
ZA
South Africa
Prior art keywords
dihydropyridines
manufacture
processes
new
Prior art date
Application number
ZA00753580A
Other languages
English (en)
Inventor
H Kuehnis
E Habicht
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA753580B publication Critical patent/ZA753580B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00753580A 1974-06-04 1975-06-03 New 1,4-dihydropyridines and processes for their manufacture ZA753580B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH763874A CH607848A5 (ru) 1974-06-04 1974-06-04

Publications (1)

Publication Number Publication Date
ZA753580B true ZA753580B (en) 1976-05-26

Family

ID=4328235

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00753580A ZA753580B (en) 1974-06-04 1975-06-03 New 1,4-dihydropyridines and processes for their manufacture

Country Status (17)

Country Link
US (1) US4017629A (ru)
JP (1) JPS6025423B2 (ru)
AT (1) AT345289B (ru)
BE (1) BE829807A (ru)
CA (1) CA1068706A (ru)
CH (1) CH607848A5 (ru)
DE (1) DE2524277A1 (ru)
DK (1) DK178775A (ru)
ES (1) ES438125A1 (ru)
FR (1) FR2273538A1 (ru)
GB (1) GB1464324A (ru)
HU (1) HU171870B (ru)
IE (1) IE41251B1 (ru)
IL (1) IL47413A (ru)
NL (1) NL7506467A (ru)
SE (1) SE425660B (ru)
ZA (1) ZA753580B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
US4525478A (en) * 1975-07-02 1985-06-25 Fujisawa Pharmaceutical Co., Ltd. Certain 4-aryl-1,4-dihydro-3,5-pyridinedicarboxylates having vasodilating and anti-hypertensive properties
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
DE2639498A1 (de) * 1976-09-02 1978-03-09 Bayer Ag Neue schwefelhaltige amino-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
DE2747513A1 (de) * 1977-10-22 1979-05-03 Bayer Ag Dihydropyridine mit schwefelhaltigen estergruppierungen
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
US4491582A (en) * 1983-03-03 1985-01-01 Usv Pharmaceutical Corporation N-(substituted piperazino)-1,4-dihydropyridine-3,5-carboxylic acid
DE3501695A1 (de) * 1985-01-19 1986-07-24 Bayer Ag, 5090 Leverkusen Verwendung von sulfonyl-dihydropyridinen als arzneimittel zur behandlung von asthma
ZA863578B (en) * 1985-06-21 1987-02-25 Hoffmann La Roche Dihydropyridine derivatives
JPS61293972A (ja) * 1985-06-24 1986-12-24 Nisshin Flour Milling Co Ltd １，４−ジヒドロピリジンスルホン誘導体およびその製法
US4889866A (en) * 1987-06-11 1989-12-26 Syntex (U.S.A.) Inc. Arylsulfonyl dihydropyridine derivatives
US5128474A (en) * 1987-07-10 1992-07-07 Ishihara Sangyo Kaisha Ltd. Mercapto-substituted pyridine compounds, aminocarbonyl-substituted pyridinesulfinic acid compounds and process for preparing the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2210672C3 (de) * 1972-03-06 1980-03-20 Bayer Ag, 5090 Leverkusen N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
GB1464324A (en) 1977-02-09
JPS6025423B2 (ja) 1985-06-18
FR2273538A1 (fr) 1976-01-02
CA1068706A (en) 1979-12-25
IL47413A (en) 1978-10-31
SE425660B (sv) 1982-10-25
DE2524277C2 (ru) 1988-08-04
IE41251B1 (en) 1979-11-21
NL7506467A (nl) 1975-12-08
IE41251L (en) 1975-12-04
ES438125A1 (es) 1977-05-16
HU171870B (hu) 1978-04-28
AT345289B (de) 1978-09-11
SE7505473L (sv) 1975-12-05
CH607848A5 (ru) 1978-11-30
DK178775A (da) 1975-12-05
FR2273538B1 (ru) 1978-11-10
ATA420075A (de) 1978-01-15
US4017629A (en) 1977-04-12
JPS514179A (en) 1976-01-14
AU8178875A (en) 1976-12-09
BE829807A (fr) 1975-12-03
IL47413A0 (en) 1975-08-31
DE2524277A1 (de) 1975-12-18

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