ZA753076B - Chroman derivatives - Google Patents

Chroman derivatives

Info

Publication number
ZA753076B
ZA753076B ZA00753076A ZA753076A ZA753076B ZA 753076 B ZA753076 B ZA 753076B ZA 00753076 A ZA00753076 A ZA 00753076A ZA 753076 A ZA753076 A ZA 753076A ZA 753076 B ZA753076 B ZA 753076B
Authority
ZA
South Africa
Prior art keywords
chroman derivatives
chroman
derivatives
Prior art date
Application number
ZA00753076A
Other languages
English (en)
Inventor
E Watts
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of ZA753076B publication Critical patent/ZA753076B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA00753076A 1974-05-31 1975-05-13 Chroman derivatives ZA753076B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24348/74A GB1495526A (en) 1974-05-31 1974-05-31 Chroman derivatives

Publications (1)

Publication Number Publication Date
ZA753076B true ZA753076B (en) 1976-05-26

Family

ID=10210307

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00753076A ZA753076B (en) 1974-05-31 1975-05-13 Chroman derivatives

Country Status (15)

Country Link
US (1) US4048317A (cs)
JP (2) JPS6044308B2 (cs)
BE (1) BE829611A (cs)
CA (1) CA1072090A (cs)
DE (1) DE2523281A1 (cs)
DK (1) DK244875A (cs)
ES (1) ES438072A1 (cs)
FR (1) FR2272659B1 (cs)
GB (1) GB1495526A (cs)
HK (1) HK20781A (cs)
IE (1) IE41539B1 (cs)
KE (1) KE3124A (cs)
MY (1) MY8100356A (cs)
NL (1) NL7506421A (cs)
ZA (1) ZA753076B (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4542150A (en) * 1975-09-17 1985-09-17 Cornell Research Foundation, Inc. Anti-juvenile hormones
US4391815A (en) * 1976-04-02 1983-07-05 Beecham Group Limited Cyanobenzano[b]pyrans
GB1511187A (en) * 1976-04-02 1978-05-17 Beecham Group Ltd Chromans
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
US4203895A (en) * 1978-04-14 1980-05-20 Warner-Lambert Company Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
DE2965739D1 (en) * 1978-10-04 1983-07-28 Beecham Group Plc Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them
DE3064285D1 (en) * 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
EP0028064B1 (en) * 1979-09-28 1983-07-20 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
GB2064514B (en) * 1979-10-29 1984-01-18 Maruko Pharmaceutical Co Flavan compounds and acid addition salts thereof and pharmaceutical compositions thereof
EP0033612B1 (en) 1980-02-02 1984-04-11 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
EP0033613A1 (en) * 1980-02-02 1981-08-12 Beecham Group Plc Chromanol derivatives, a process for their preparation and compositions containing them
EP0046652B1 (en) * 1980-08-21 1985-05-22 Beecham Group Plc Chromanol derivatives, their production and pharmaceutical compositions containing them
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
JPS59110690A (ja) * 1982-12-16 1984-06-26 Dai Ichi Seiyaku Co Ltd ベンゾピラン誘導体
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
CA1308108C (en) * 1987-10-27 1992-09-29 Dominick A. Quagliato Antihypertensive benzopyran derivatives
FR2637896B1 (fr) * 1988-10-17 1990-11-30 Adir Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
HU222726B1 (hu) * 1990-02-06 2003-09-29 Pfizer, Inc., Piperidinszármazékok, eljárás elżállításukra és az ezeket tartalmazó gyógyszerkészítmények
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
AU684568B2 (en) * 1994-01-31 1997-12-18 Pfizer Inc. Neuroprotective chroman compounds
WO1997023209A1 (fr) * 1995-12-25 1997-07-03 Nissan Chemical Industries, Ltd. Agent therapeutique contre l'insuffisance cardiaque
ATE242230T1 (de) * 1996-07-26 2003-06-15 Nissan Chemical Ind Ltd Chroman derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518273A (en) * 1966-08-03 1970-06-30 Warner Lambert Pharmaceutical Benzopyranquinolinol derivatives and process for their production
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
US3743659A (en) * 1971-08-25 1973-07-03 Riker Laboratories Inc Substituted isochromans and processes therefor

Also Published As

Publication number Publication date
CA1072090A (en) 1980-02-19
GB1495526A (en) 1977-12-21
AU8169375A (en) 1976-12-02
NL7506421A (nl) 1975-12-02
JPS60231681A (ja) 1985-11-18
DE2523281A1 (de) 1975-12-11
HK20781A (en) 1981-05-22
IE41539B1 (en) 1980-01-30
JPS6044308B2 (ja) 1985-10-02
KE3124A (en) 1981-05-15
FR2272659A1 (cs) 1975-12-26
MY8100356A (en) 1981-12-31
JPS511477A (cs) 1976-01-08
DK244875A (da) 1975-12-01
FR2272659B1 (cs) 1980-02-08
ES438072A1 (es) 1977-01-16
US4048317A (en) 1977-09-13
IE41539L (en) 1975-11-30
JPS6160077B2 (cs) 1986-12-19
BE829611A (fr) 1975-11-28

Similar Documents

Publication Publication Date Title
KE3124A (en) Chroman derivatives
PH11652A (en) Arloxphenylpropylamines derivatives
ZA7548B (en) 2-aryl-4-substituted piperidinoalkanol derivatives
GB1519811A (en) Thienothaiazine derivatives
PH12312A (en) Thienothiazine derivatives
ZA757828B (en) 2-methoxy-benzamide derivatives
AU1038176A (en) 4-arylpiperidine derivatives
AU7921975A (en) Hexahydro-alpha-carboline derivatives
GB1484049A (en) 3-alkoxy-pyrazine-2-carboxamide derivatives
GB1521320A (en) Quinolisidine derivatives
PH13802A (en) 7-hydroxy pestradiol derivative
ZA753315B (en) Oxacyclohexane derivatives
PH12265A (en) Benzo-bicyclononene derivatives
PH11562A (en) Benzofuran derivatives
ZA755543B (en) Thiomethylcephem derivatives
ZA756893B (en) Phenyl-pyridylamine derivatives
ZA753299B (en) Amidino-hydrazone derivatives
JPS51115457A (en) 166methyll9 alphaa halosteroid derivatives
GB1486646A (en) Thieno-pyridine derivatives
AU8181575A (en) Benzodioxan derivatives
AU8162975A (en) Benzazine derivatives
HK28879A (en) 2-aminomethylphenol derivatives
HK43378A (en) Hexahydrodibenzofuran-3-one derivatives
ZA755239B (en) Abietamide derivatives
AU484871B2 (en) Chroman derivatives