ZA733012B - New acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions - Google Patents

New acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions

Info

Publication number
ZA733012B
ZA733012B ZA733012A ZA733012A ZA733012B ZA 733012 B ZA733012 B ZA 733012B ZA 733012 A ZA733012 A ZA 733012A ZA 733012 A ZA733012 A ZA 733012A ZA 733012 B ZA733012 B ZA 733012B
Authority
ZA
South Africa
Prior art keywords
derivatives
preparing
pharmaceutical compositions
acylamino acids
new
Prior art date
Application number
ZA733012A
Other languages
English (en)
Inventor
M Vincent
J Duhault
X Pascaud
L Beregi
G Remond
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Publication of ZA733012B publication Critical patent/ZA733012B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/60Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA733012A 1972-05-05 1973-05-03 New acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions ZA733012B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2109572A GB1406054A (en) 1972-05-05 1972-05-05 Acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ZA733012B true ZA733012B (en) 1974-03-27

Family

ID=10157139

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA733012A ZA733012B (en) 1972-05-05 1973-05-03 New acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions

Country Status (18)

Country Link
US (1) US3876683A (da)
JP (1) JPS5246222B2 (da)
AR (1) AR197040A1 (da)
AT (1) AT323136B (da)
BE (1) BE799144A (da)
CA (1) CA1008084A (da)
CH (1) CH576425A5 (da)
ES (1) ES414362A1 (da)
FR (1) FR2183765B1 (da)
GB (1) GB1406054A (da)
HU (1) HU165742B (da)
IE (1) IE37586B1 (da)
NL (1) NL7306141A (da)
NO (1) NO140421C (da)
OA (1) OA04368A (da)
SE (1) SE408057B (da)
SU (1) SU489310A3 (da)
ZA (1) ZA733012B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341798A (en) * 1980-07-22 1982-07-27 Laboratori Prophin S.P.A. Amide derivatives of p-isobutyl-phenyl-propionic acids and related pharmaceutical compositions
JPS6322657Y2 (da) * 1981-04-21 1988-06-22
GB2177769B (en) * 1985-07-17 1989-07-26 Guest John D Improvements in or relating to hose connectors
US6153652A (en) 1996-11-22 2000-11-28 Elan Pharmaceuticals, Inc. N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6117901A (en) 1996-11-22 2000-09-12 Athena Neurosciences, Inc. N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use
US6642261B2 (en) 1997-11-21 2003-11-04 Athena Neurosciences, Inc. N-(aryl/heteroarylacety) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3043868A (en) * 1959-12-09 1962-07-10 Searle & Co N-xenylalkanoylaminoalkanoic acids and esters thereof
US3770821A (en) * 1970-10-16 1973-11-06 Miles Lab Substituted beta-arylamidoacrylic acids

Also Published As

Publication number Publication date
NO140421B (no) 1979-05-21
ES414362A1 (es) 1976-02-01
DE2321392B2 (de) 1976-07-29
CH576425A5 (da) 1976-06-15
OA04368A (fr) 1980-01-31
SE408057B (sv) 1979-05-14
JPS5246222B2 (da) 1977-11-22
SU489310A3 (ru) 1975-10-25
DE2321392A1 (de) 1973-11-15
FR2183765A1 (da) 1973-12-21
US3876683A (en) 1975-04-08
FR2183765B1 (da) 1976-05-14
IE37586L (en) 1973-11-05
NL7306141A (da) 1973-11-07
BE799144A (fr) 1973-11-05
AR197040A1 (es) 1974-03-08
JPS4947353A (da) 1974-05-08
CA1008084A (fr) 1977-04-05
GB1406054A (en) 1975-09-10
AU5425273A (en) 1974-10-10
SE7306289L (da) 1973-11-06
NO140421C (no) 1979-08-29
HU165742B (da) 1974-10-28
AT323136B (de) 1975-06-25
IE37586B1 (en) 1977-08-31

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