ZA725664B - Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture - Google Patents
Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufactureInfo
- Publication number
- ZA725664B ZA725664B ZA725664A ZA725664A ZA725664B ZA 725664 B ZA725664 B ZA 725664B ZA 725664 A ZA725664 A ZA 725664A ZA 725664 A ZA725664 A ZA 725664A ZA 725664 B ZA725664 B ZA 725664B
- Authority
- ZA
- South Africa
- Prior art keywords
- iodinated
- tri
- methyl
- manufacture
- dicarboxylic acid
- Prior art date
Links
- 229940051881 anilide analgesics and antipyretics Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2141803A DE2141803A1 (de) | 1971-08-17 | 1971-08-17 | Trijodierte n-methyl-dicarbonsaeureani-lide und verfahren zu iher herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA725664B true ZA725664B (en) | 1973-05-30 |
Family
ID=5817319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA725664A ZA725664B (en) | 1971-08-17 | 1972-08-17 | Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4001298A (da) |
| JP (1) | JPS4829736A (da) |
| AR (1) | AR204073A1 (da) |
| AT (2) | AT329543B (da) |
| AU (1) | AU476763B2 (da) |
| BE (1) | BE787669A (da) |
| CA (1) | CA977759A (da) |
| DD (1) | DD100156A5 (da) |
| DE (1) | DE2141803A1 (da) |
| DK (1) | DK132375C (da) |
| ES (2) | ES405770A1 (da) |
| FR (1) | FR2150784B1 (da) |
| GB (1) | GB1409733A (da) |
| HU (1) | HU164151B (da) |
| IL (1) | IL40088A (da) |
| NL (1) | NL7209286A (da) |
| SU (1) | SU474974A3 (da) |
| ZA (1) | ZA725664B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4225725A (en) * | 1975-10-20 | 1980-09-30 | Mallinckrodt, Inc. | Lower alkoxymethyl esters of 2,4,6-triiodobenzoic acid derivatives |
| GB1539791A (en) * | 1976-04-08 | 1979-02-07 | Guerbet Sa | X-ray contrast media |
| DE2628517C2 (de) * | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
| DE2629228C2 (de) * | 1976-06-25 | 1984-10-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung |
| EP0079397A1 (de) * | 1981-11-13 | 1983-05-25 | Schering Aktiengesellschaft | Unsymmetrisch substituierte Dicarbonsäure-bis-(2,4,-6-trijodanilide), deren Herstellung und diese enthaltende Röntgenkontrastmittel |
| KR960016747B1 (ko) * | 1987-05-22 | 1996-12-20 | 브라코 인터내셔날 비. 브이 | 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법 |
| US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
| US5869024A (en) * | 1989-11-29 | 1999-02-09 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
| US5527926A (en) * | 1990-11-26 | 1996-06-18 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
| US5278311A (en) * | 1992-06-05 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Nonionic radiographic contrast agents |
| US5463080A (en) * | 1992-08-27 | 1995-10-31 | Bracco International B.V. | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542861A (en) * | 1967-05-08 | 1970-11-24 | Sterling Drug Inc | 3-amino-5-cycloalkylcarbonylamino-2,4,6-triiodobenzoic acids |
| US3732293A (en) * | 1968-03-15 | 1973-05-08 | Sterling Drug Inc | Iodinated bis(aminobenzoic acids) and esters thereof |
-
0
- BE BE787669D patent/BE787669A/xx unknown
-
1971
- 1971-08-17 DE DE2141803A patent/DE2141803A1/de active Pending
-
1972
- 1972-01-01 AR AR243597A patent/AR204073A1/es active
- 1972-06-30 NL NL7209286A patent/NL7209286A/xx unknown
- 1972-07-06 DD DD164237A patent/DD100156A5/xx unknown
- 1972-07-07 DK DK340372A patent/DK132375C/da active
- 1972-08-03 SU SU1817911A patent/SU474974A3/ru active
- 1972-08-07 GB GB3673472A patent/GB1409733A/en not_active Expired
- 1972-08-09 IL IL40088A patent/IL40088A/en unknown
- 1972-08-11 ES ES405770A patent/ES405770A1/es not_active Expired
- 1972-08-11 ES ES405769A patent/ES405769A1/es not_active Expired
- 1972-08-14 AT AT713473*7A patent/AT329543B/de not_active IP Right Cessation
- 1972-08-14 AT AT700972A patent/AT317417B/de not_active IP Right Cessation
- 1972-08-16 HU HU72SE405A patent/HU164151B/hu unknown
- 1972-08-16 FR FR7229332A patent/FR2150784B1/fr not_active Expired
- 1972-08-16 AU AU45650/72A patent/AU476763B2/en not_active Expired
- 1972-08-17 JP JP47082447A patent/JPS4829736A/ja active Pending
- 1972-08-17 ZA ZA725664A patent/ZA725664B/xx unknown
- 1972-08-17 CA CA149,662A patent/CA977759A/en not_active Expired
- 1972-08-17 US US05/281,379 patent/US4001298A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DD100156A5 (da) | 1973-09-12 |
| FR2150784A1 (da) | 1973-04-13 |
| IL40088A0 (en) | 1972-10-29 |
| HU164151B (da) | 1973-12-28 |
| DK132375B (da) | 1975-12-01 |
| AT329543B (de) | 1976-05-10 |
| US4001298A (en) | 1977-01-04 |
| ES405769A1 (es) | 1975-09-16 |
| GB1409733A (en) | 1975-10-15 |
| NL7209286A (da) | 1973-02-20 |
| JPS4829736A (da) | 1973-04-19 |
| SU474974A3 (ru) | 1975-06-25 |
| AU476763B2 (en) | 1976-10-07 |
| AR204073A1 (es) | 1975-11-20 |
| CA977759A (en) | 1975-11-11 |
| DE2141803A1 (de) | 1973-03-01 |
| DK132375C (da) | 1976-05-03 |
| FR2150784B1 (da) | 1975-06-20 |
| BE787669A (fr) | 1973-02-19 |
| AT317417B (de) | 1974-08-26 |
| ATA713473A (de) | 1975-08-15 |
| ES405770A1 (es) | 1975-09-16 |
| IL40088A (en) | 1976-05-31 |
| AU4565072A (en) | 1974-02-21 |
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