ZA716912B - Antithrombogenic process and composition - Google Patents
Antithrombogenic process and compositionInfo
- Publication number
- ZA716912B ZA716912B ZA716912A ZA716912A ZA716912B ZA 716912 B ZA716912 B ZA 716912B ZA 716912 A ZA716912 A ZA 716912A ZA 716912 A ZA716912 A ZA 716912A ZA 716912 B ZA716912 B ZA 716912B
- Authority
- ZA
- South Africa
- Prior art keywords
- antithrombogenic
- composition
- antithrombogenic process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00082839A US3800039A (en) | 1970-10-21 | 1970-10-21 | Antithrombogenic process employing substituted 6,7-dialkoxyquinazolines |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA716912B true ZA716912B (en) | 1972-06-28 |
Family
ID=22173777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA716912A ZA716912B (en) | 1970-10-21 | 1971-10-15 | Antithrombogenic process and composition |
Country Status (9)
Country | Link |
---|---|
US (1) | US3800039A (xx) |
AU (1) | AU470693B2 (xx) |
BE (1) | BE774161A (xx) |
DE (1) | DE2152521A1 (xx) |
FR (1) | FR2111749B1 (xx) |
GB (1) | GB1364307A (xx) |
NL (1) | NL7114287A (xx) |
PH (1) | PH10260A (xx) |
ZA (1) | ZA716912B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1520611A (en) * | 1976-06-11 | 1978-08-09 | Wyeth John & Brother Ltd | Fused ring indole derivatives |
IL89029A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them |
IL89028A0 (en) * | 1988-01-29 | 1989-08-15 | Lilly Co Eli | Quinoline,quinazoline and cinnoline derivatives |
US5114939A (en) * | 1988-01-29 | 1992-05-19 | Dowelanco | Substituted quinolines and cinnolines as fungicides |
US5411963A (en) * | 1988-01-29 | 1995-05-02 | Dowelanco | Quinazoline derivatives |
IL89027A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Quinazoline derivatives, process for their preparation and fungicidal, insecticidal and miticidal compositions containing them |
US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
US6645969B1 (en) * | 1991-05-10 | 2003-11-11 | Aventis Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase |
EP0634169B1 (en) * | 1993-06-29 | 2000-01-05 | Takeda Chemical Industries, Ltd. | Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis |
AU5984296A (en) * | 1995-06-07 | 1996-12-30 | Sugen, Inc. | Quinazolines and pharmaceutical compositions |
US6706721B1 (en) * | 1998-04-29 | 2004-03-16 | Osi Pharmaceuticals, Inc. | N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate |
UA74803C2 (uk) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування |
US7087613B2 (en) * | 1999-11-11 | 2006-08-08 | Osi Pharmaceuticals, Inc. | Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
JP2003518023A (ja) | 1999-11-30 | 2003-06-03 | パーカー ヒューズ インスティテュート | トロンビン誘導血小板凝集の阻害剤 |
EP1330444B1 (en) | 2000-11-01 | 2011-03-23 | Millennium Pharmaceuticals, Inc. | Nitrogenous heterocyclic compounds and process for making them |
AU2001229722A1 (en) * | 2000-11-29 | 2002-06-11 | Parker Hughes Institute | Inhibitors of thrombin induced platelet aggregation |
JP2002293773A (ja) * | 2001-03-30 | 2002-10-09 | Sumika Fine Chemicals Co Ltd | キナゾリン誘導体の製造方法 |
US8246966B2 (en) * | 2006-08-07 | 2012-08-21 | University Of Georgia Research Foundation, Inc. | Trypanosome microsome system and uses thereof |
US8338433B2 (en) * | 2006-11-22 | 2012-12-25 | University Of Georgia Research Foundation, Inc. | Tyrosine kinase inhibitors as anti-kinetoplastid agents |
WO2009057139A2 (en) * | 2007-10-29 | 2009-05-07 | Natco Pharma Limited | Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248292A (en) * | 1963-02-06 | 1966-04-26 | Mead Johnson & Co | Pharmaceutically active dimethoxyquinazolines |
US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
US3631035A (en) * | 1969-04-02 | 1971-12-28 | Pfizer | 2-vinyl-1 4-dihydroquinazoline derivatives |
-
1970
- 1970-10-21 US US00082839A patent/US3800039A/en not_active Expired - Lifetime
-
1971
- 1971-10-15 ZA ZA716912A patent/ZA716912B/xx unknown
- 1971-10-18 NL NL7114287A patent/NL7114287A/xx unknown
- 1971-10-19 BE BE774161A patent/BE774161A/xx unknown
- 1971-10-19 PH PH12946A patent/PH10260A/en unknown
- 1971-10-19 AU AU34758/71A patent/AU470693B2/en not_active Expired
- 1971-10-20 FR FR7137740A patent/FR2111749B1/fr not_active Expired
- 1971-10-20 GB GB4882271A patent/GB1364307A/en not_active Expired
- 1971-10-21 DE DE19712152521 patent/DE2152521A1/de active Pending
Also Published As
Publication number | Publication date |
---|---|
NL7114287A (xx) | 1972-04-25 |
AU3475871A (en) | 1973-05-03 |
AU470693B2 (en) | 1976-03-25 |
FR2111749B1 (xx) | 1975-04-18 |
DE2152521A1 (de) | 1972-04-27 |
PH10260A (en) | 1976-10-20 |
US3800039A (en) | 1974-03-26 |
BE774161A (fr) | 1972-04-19 |
GB1364307A (en) | 1974-08-21 |
FR2111749A1 (xx) | 1972-06-09 |
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