ZA715769B - 1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamides - Google Patents
1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamidesInfo
- Publication number
- ZA715769B ZA715769B ZA715769A ZA715769A ZA715769B ZA 715769 B ZA715769 B ZA 715769B ZA 715769 A ZA715769 A ZA 715769A ZA 715769 A ZA715769 A ZA 715769A ZA 715769 B ZA715769 B ZA 715769B
- Authority
- ZA
- South Africa
- Prior art keywords
- tetrahydroisoquinoline
- carboxamides
- thio
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6859170A | 1970-08-31 | 1970-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA715769B true ZA715769B (en) | 1972-04-26 |
Family
ID=22083517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA715769A ZA715769B (en) | 1970-08-31 | 1971-08-30 | 1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3745162A (fa) |
| JP (1) | JPS4843509B2 (fa) |
| AU (1) | AU448869B2 (fa) |
| CA (1) | CA934378A (fa) |
| CH (1) | CH529137A (fa) |
| DE (1) | DE2143589A1 (fa) |
| ES (1) | ES394541A1 (fa) |
| FR (1) | FR2103641B1 (fa) |
| GB (1) | GB1331710A (fa) |
| ZA (1) | ZA715769B (fa) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947456A (en) * | 1970-01-06 | 1976-03-30 | Hoffman-La Roche Inc. | Substituted 4-phenyl isoquinolines |
| US3872125A (en) * | 1973-03-03 | 1975-03-18 | Sandoz Ag | 3-substituted-4-aryl isoquinolines |
| US3910915A (en) * | 1973-07-23 | 1975-10-07 | Searle & Co | 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines |
| US3870722A (en) * | 1973-11-02 | 1975-03-11 | Sandoz Ag | 2-Methyl-3-substituted-4-aryl isoquinolines |
| GB1463667A (en) * | 1973-12-17 | 1977-02-02 | Wyeth John & Brother Ltd | Process for preparing thioamides |
| US4092418A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-carbothioamides of 1,5-naphthyridine derivatives |
| US4092320A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-(N-acyl)-carbothioamides of 1,5-naphthyridine derivatives |
| US4410699A (en) * | 1981-08-07 | 1983-10-18 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydro-4-isoquinolinols |
| RU2572826C2 (ru) | 2008-12-02 | 2016-01-20 | Чиралджен, Лтд. | Способ синтеза модифицированных по атому фосфора нуклеиновых кислот |
| SG10201403841QA (en) | 2009-07-06 | 2014-09-26 | Ontorii Inc | Novel nucleic acid prodrugs and methods of use thereof |
| JP5868324B2 (ja) * | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| CN107365339A (zh) | 2011-07-19 | 2017-11-21 | 波涛生命科学有限公司 | 合成官能化核酸的方法 |
| RU2693381C2 (ru) | 2012-07-13 | 2019-07-02 | Уэйв Лайф Сайенсес Лтд. | Асимметричная вспомогательная группа |
| WO2014010718A1 (ja) | 2012-07-13 | 2014-01-16 | 株式会社新日本科学 | キラル核酸アジュバント |
| EP2872147B1 (en) | 2012-07-13 | 2022-12-21 | Wave Life Sciences Ltd. | Method for making chiral oligonucleotides |
| EP3095459A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
| JPWO2015108047A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| CA2936712A1 (en) | 2014-01-16 | 2015-07-23 | Meena | Chiral design |
-
1970
- 1970-08-31 US US00068591A patent/US3745162A/en not_active Expired - Lifetime
-
1971
- 1971-08-25 GB GB3994471A patent/GB1331710A/en not_active Expired
- 1971-08-25 AU AU32712/71A patent/AU448869B2/en not_active Expired
- 1971-08-26 ES ES394541A patent/ES394541A1/es not_active Expired
- 1971-08-26 JP JP46064812A patent/JPS4843509B2/ja not_active Expired
- 1971-08-30 CH CH1269271A patent/CH529137A/fr not_active IP Right Cessation
- 1971-08-30 CA CA121716A patent/CA934378A/en not_active Expired
- 1971-08-30 ZA ZA715769A patent/ZA715769B/xx unknown
- 1971-08-30 FR FR7131357A patent/FR2103641B1/fr not_active Expired
- 1971-08-31 DE DE19712143589 patent/DE2143589A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU448869B2 (en) | 1974-05-30 |
| AU3271271A (en) | 1973-03-01 |
| CA934378A (en) | 1973-09-25 |
| JPS475678A (fa) | 1972-03-25 |
| FR2103641B1 (fa) | 1974-10-18 |
| FR2103641A1 (fa) | 1972-04-14 |
| ES394541A1 (es) | 1974-10-16 |
| US3745162A (en) | 1973-07-10 |
| JPS4843509B2 (fa) | 1973-12-19 |
| DE2143589A1 (de) | 1972-03-09 |
| GB1331710A (en) | 1973-09-26 |
| CH529137A (fr) | 1972-10-15 |
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