ZA202204075B - Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof - Google Patents

Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof

Info

Publication number
ZA202204075B
ZA202204075B ZA2022/04075A ZA202204075A ZA202204075B ZA 202204075 B ZA202204075 B ZA 202204075B ZA 2022/04075 A ZA2022/04075 A ZA 2022/04075A ZA 202204075 A ZA202204075 A ZA 202204075A ZA 202204075 B ZA202204075 B ZA 202204075B
Authority
ZA
South Africa
Prior art keywords
addiction
treatment
cytisine
subjects
prevention
Prior art date
Application number
ZA2022/04075A
Other languages
English (en)
Inventor
A Jacobs Cindy
F Cain Daniel
Clarke Anthony
Original Assignee
Achieve Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achieve Life Sciences Inc filed Critical Achieve Life Sciences Inc
Publication of ZA202204075B publication Critical patent/ZA202204075B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2022/04075A 2019-09-12 2022-04-11 Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof ZA202204075B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962899637P 2019-09-12 2019-09-12
US202062988890P 2020-03-12 2020-03-12
PCT/US2020/046308 WO2021050203A1 (en) 2019-09-12 2020-08-14 Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof

Publications (1)

Publication Number Publication Date
ZA202204075B true ZA202204075B (en) 2023-11-29

Family

ID=74866435

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2022/04075A ZA202204075B (en) 2019-09-12 2022-04-11 Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof

Country Status (11)

Country Link
US (3) US11083715B2 (https=)
EP (1) EP4027815B1 (https=)
JP (2) JP7742832B2 (https=)
KR (1) KR20220074895A (https=)
CN (4) CN119587493A (https=)
AU (1) AU2020346695A1 (https=)
BR (1) BR112022004519A2 (https=)
CA (1) CA3153405A1 (https=)
MX (1) MX2022002882A (https=)
WO (1) WO2021050203A1 (https=)
ZA (1) ZA202204075B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3153405A1 (en) * 2019-09-12 2021-03-18 Achieve Life Sciences, Inc. Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof
EP4399517A4 (en) * 2021-09-08 2025-10-15 Achieve Life Sciences Inc ANALYTICAL METHODS FOR EVALUATING THE PURITY OF CYTISINE
JP2024095092A (ja) * 2022-12-28 2024-07-10 株式会社日立製作所 生成装置、生成方法、および生成プログラム
WO2024226736A2 (en) * 2023-04-26 2024-10-31 Achieve Life Sciences, Inc. Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125699B (en) 1982-02-22 1986-02-12 Bruss Ni Sanitarno Gigieniches Medicinal preparation having antinicotine effect and method for obtention thereof
WO1998018798A1 (en) * 1996-10-30 1998-05-07 Pfizer Inc. Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and their use in addiction therapy
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
CN104906669A (zh) * 2007-03-30 2015-09-16 菲利普莫里斯生产公司 用于输送药剂的装置和方法
CN103284319A (zh) * 2013-06-20 2013-09-11 昌宁德康生物科技有限公司 一种金雀花碱替代尼古丁口腔雾化液及其制备方法
WO2014205449A2 (en) * 2013-06-21 2014-12-24 Isis Pharmaceuticals, Inc. Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic profile
JP6324964B2 (ja) 2013-08-23 2018-05-16 久光製薬株式会社 貼付剤
PL409829A1 (pl) * 2014-10-18 2016-04-25 Łukasz Zalewski Płyn z cytyzyną do elektronicznych papierosów
GB201602145D0 (en) * 2016-02-05 2016-03-23 Achieve Pharma Uk Ltd Salt
EP3658561A1 (en) * 2017-07-24 2020-06-03 Achieve Pharma UK Limited Cytisine salts
CA3153405A1 (en) * 2019-09-12 2021-03-18 Achieve Life Sciences, Inc. Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof

Also Published As

Publication number Publication date
EP4027815A4 (en) 2023-06-07
AU2020346695A1 (en) 2022-04-28
WO2021050203A1 (en) 2021-03-18
KR20220074895A (ko) 2022-06-03
JP2022548876A (ja) 2022-11-22
EP4027815A1 (en) 2022-07-20
CN114727647A (zh) 2022-07-08
US20210330652A1 (en) 2021-10-28
CN118286217A (zh) 2024-07-05
US20210077475A1 (en) 2021-03-18
EP4027815B1 (en) 2026-04-15
CN119564619A (zh) 2025-03-07
US20210077473A1 (en) 2021-03-18
CN119587493A (zh) 2025-03-11
MX2022002882A (es) 2022-05-10
US11083715B2 (en) 2021-08-10
JP7742832B2 (ja) 2025-09-22
CA3153405A1 (en) 2021-03-18
JP2025081331A (ja) 2025-05-27
US11083716B2 (en) 2021-08-10
BR112022004519A2 (pt) 2022-05-31

Similar Documents

Publication Publication Date Title
ZA202204075B (en) Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof
IL268011B1 (en) Bifunctional benzothiophene compounds, preparations containing them and their use in therapy
WO2019090347A8 (en) Adenosine pathway inhibitors for cancer treatment
WO2019006005A3 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF MELANOMA
HK1252937A1 (zh) 用於治疗抑郁症的方法和试剂盒
MX2019014548A (es) Derivado de n2,n4-difenilprimidin-2,4-diamina, metodo para la preparacion del mismo, y una composicion farmaceutica que contiene el mismo como ingrediente activo para la prevencion o tratamiento de cancer.
ZA201800056B (en) Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders
SG10201908697XA (en) A pharmaceutical composition for use in the treatment or prevention of a c5-related disease and a method for treating or preventing a c5-related disease
MY187540A (en) Compounds active towards bromodomains
MX387885B (es) Inhibidores de ezh2 para tratar linfomas.
MY196631A (en) Antibody Agents Specific for Human Cd19 and uses Thereof
WO2016025635A3 (en) Combination therapy for treating cancer
MX2019008701A (es) Terapia de combinacion que involucra compuestos macrociclicos de diarilo.
MX2021004755A (es) Uso de plasma y fracciones de plasma para mejorar el dolor, la cicatrizacion de heridas y la recuperacion posoperatoria.
EP4286013A3 (en) Lrrc33 inhibitors and use thereof
MX2017014436A (es) Compuestos biciclicos.
HK1258276A1 (zh) 用於治疗hiv的化合物和组合
MX2020011817A (es) Metodos para tratar el linfoma.
TW201713323A (en) Therapeutic compositions and methods of use thereof
WO2018208954A3 (en) Peptidomimetic macrocycles and uses thereof
MX2017013047A (es) Tratamiento de dolor.
MX2018002047A (es) Uso de ureidomustina (bo-1055) en el tratamiento del cancer.
PH12017500505A1 (en) Veliparib in combination with carboplatin and paclitaxel for the treatment of non-small cell lung cancer in smokers
WO2024226736A3 (en) Compositions comprising cytisine in the treatment and/or prevention of addiction in subjects in need thereof
MX2020012805A (es) Compuestos para el tratamiento del dolor, composiciones que comprenden los mismos, y metodos para utilizar los mismos.