ZA201706348B - Heterocyclic compounds and their use in preventing or treating bacterial infections - Google Patents
Heterocyclic compounds and their use in preventing or treating bacterial infectionsInfo
- Publication number
- ZA201706348B ZA201706348B ZA201706348A ZA201706348A ZA201706348B ZA 201706348 B ZA201706348 B ZA 201706348B ZA 201706348 A ZA201706348 A ZA 201706348A ZA 201706348 A ZA201706348 A ZA 201706348A ZA 201706348 B ZA201706348 B ZA 201706348B
- Authority
- ZA
- South Africa
- Prior art keywords
- preventing
- heterocyclic compounds
- bacterial infections
- treating bacterial
- treating
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305508.2A EP3075381A1 (en) | 2015-04-03 | 2015-04-03 | Heterocyclic compounds and their use in preventing or treating bacterial infections |
| EP16305069 | 2016-01-26 | ||
| PCT/EP2016/057274 WO2016156597A1 (en) | 2015-04-03 | 2016-04-01 | Heterocyclic compounds and their use in preventing or treating bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201706348B true ZA201706348B (en) | 2019-11-27 |
Family
ID=55646608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA201706348A ZA201706348B (en) | 2015-04-03 | 2017-09-20 | Heterocyclic compounds and their use in preventing or treating bacterial infections |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10501481B2 (enExample) |
| EP (1) | EP3277277B1 (enExample) |
| JP (1) | JP2018510198A (enExample) |
| KR (1) | KR20170132316A (enExample) |
| CN (1) | CN107438614B (enExample) |
| AU (1) | AU2016239861A1 (enExample) |
| BR (1) | BR112017020935A2 (enExample) |
| CA (1) | CA2980395A1 (enExample) |
| CL (1) | CL2017002482A1 (enExample) |
| MX (1) | MX2017012545A (enExample) |
| RU (1) | RU2714197C2 (enExample) |
| TW (1) | TW201639854A (enExample) |
| WO (1) | WO2016156597A1 (enExample) |
| ZA (1) | ZA201706348B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| WO2015123424A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| LT3105218T (lt) | 2014-02-13 | 2019-12-10 | Incyte Corp | Ciklopropilaminai kaip lsd1 inhibitoriai |
| WO2016007736A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyrazines as lsd1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| EA201792205A1 (ru) | 2015-04-03 | 2018-02-28 | Инсайт Корпорейшн | Гетероциклические соединения как ингибиторы lsd1 |
| DK3334709T3 (da) | 2015-08-12 | 2025-02-03 | Incyte Holdings Corp | Salte af en lsd1-hæmmer |
| JOP20190061A1 (ar) * | 2016-09-28 | 2019-03-26 | Novartis Ag | مثبطات بيتا-لاكتاماز |
| EP3300736B1 (en) * | 2016-09-30 | 2021-05-05 | Mutabilis | Composition comprising antibiotic compound and an heterocyclic compound and their use in preventing or treating bacterial infections |
| EP3357924A1 (en) | 2017-02-06 | 2018-08-08 | Mutabilis | Novel heterocyclic compounds and their use in preventing or treating bacterial infections |
| EP3604315A1 (en) * | 2018-07-30 | 2020-02-05 | Mutabilis | Heterocyclic compounds and their use in preventing or treating bacterial infections |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| EP4272831A3 (en) | 2018-08-09 | 2024-02-21 | Antabio SAS | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1107541A1 (ru) | 1982-12-03 | 1995-10-20 | Институт Тонкой Органической Химии Им.А.Л.Мнджояна | 10-нитро-1,6,8-триазатрицикло [6,3,1,1] тридекан-2,5-дион |
| ATE177099T1 (de) | 1993-12-29 | 1999-03-15 | Pfizer | Diazabicyclische neurokinin antagonisten |
| FR2825705B1 (fr) * | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| US20040009234A1 (en) * | 2002-07-10 | 2004-01-15 | Meisel Gerard M. | Gastrointestinal compositions |
| US7732607B2 (en) * | 2005-08-22 | 2010-06-08 | Anatoly Mazurov | Heteroaryl-substituted diazatricycloalkanes and methods of use thereof |
| EP1972629A1 (en) * | 2007-03-23 | 2008-09-24 | Mutabilis SA | New imidazolo-heteroaryl derivatives with antibacterial properties |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2937034B1 (fr) * | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
| AR090539A1 (es) * | 2012-04-02 | 2014-11-19 | Astrazeneca Ab | COMPUESTOS INHIBIDORES DE b LACTAMASA |
| WO2014141132A1 (en) | 2013-03-14 | 2014-09-18 | Naeja Pharmaceutical Inc. | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND β-LACTAMASE INHIBITORS |
-
2016
- 2016-04-01 EP EP16713469.1A patent/EP3277277B1/en active Active
- 2016-04-01 US US15/563,889 patent/US10501481B2/en active Active
- 2016-04-01 MX MX2017012545A patent/MX2017012545A/es unknown
- 2016-04-01 JP JP2017551690A patent/JP2018510198A/ja active Pending
- 2016-04-01 WO PCT/EP2016/057274 patent/WO2016156597A1/en not_active Ceased
- 2016-04-01 RU RU2017134055A patent/RU2714197C2/ru active
- 2016-04-01 CN CN201680020682.XA patent/CN107438614B/zh active Active
- 2016-04-01 TW TW105110646A patent/TW201639854A/zh unknown
- 2016-04-01 CA CA2980395A patent/CA2980395A1/en not_active Abandoned
- 2016-04-01 KR KR1020177031671A patent/KR20170132316A/ko not_active Withdrawn
- 2016-04-01 AU AU2016239861A patent/AU2016239861A1/en not_active Abandoned
- 2016-04-01 BR BR112017020935A patent/BR112017020935A2/pt not_active Application Discontinuation
-
2017
- 2017-09-20 ZA ZA201706348A patent/ZA201706348B/en unknown
- 2017-10-02 CL CL2017002482A patent/CL2017002482A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US10501481B2 (en) | 2019-12-10 |
| CN107438614B (zh) | 2020-01-31 |
| MX2017012545A (es) | 2018-09-28 |
| JP2018510198A (ja) | 2018-04-12 |
| CN107438614A (zh) | 2017-12-05 |
| KR20170132316A (ko) | 2017-12-01 |
| EP3277277A1 (en) | 2018-02-07 |
| TW201639854A (zh) | 2016-11-16 |
| CL2017002482A1 (es) | 2018-04-20 |
| WO2016156597A1 (en) | 2016-10-06 |
| RU2017134055A (ru) | 2019-04-03 |
| RU2714197C2 (ru) | 2020-02-13 |
| CA2980395A1 (en) | 2016-10-06 |
| US20180118765A1 (en) | 2018-05-03 |
| RU2017134055A3 (enExample) | 2019-08-30 |
| EP3277277B1 (en) | 2021-01-06 |
| AU2016239861A1 (en) | 2017-10-12 |
| BR112017020935A2 (pt) | 2018-07-10 |
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