ZA201409213B - Pro-drug compounds - Google Patents
Pro-drug compoundsInfo
- Publication number
- ZA201409213B ZA201409213B ZA2014/09213A ZA201409213A ZA201409213B ZA 201409213 B ZA201409213 B ZA 201409213B ZA 2014/09213 A ZA2014/09213 A ZA 2014/09213A ZA 201409213 A ZA201409213 A ZA 201409213A ZA 201409213 B ZA201409213 B ZA 201409213B
- Authority
- ZA
- South Africa
- Prior art keywords
- pro
- drug compounds
- drug
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1211788.3A GB201211788D0 (en) | 2012-07-03 | 2012-07-03 | Pro-drug compounds |
| GBGB1304812.9A GB201304812D0 (en) | 2013-03-15 | 2013-03-15 | Pro-drug compounds |
| PCT/GB2013/051767 WO2014006407A1 (en) | 2012-07-03 | 2013-07-03 | Pro-drug compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201409213B true ZA201409213B (en) | 2016-07-27 |
Family
ID=48782540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2014/09213A ZA201409213B (en) | 2012-07-03 | 2014-12-15 | Pro-drug compounds |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9499510B2 (enExample) |
| EP (1) | EP2870148A1 (enExample) |
| AU (1) | AU2013285164A1 (enExample) |
| CA (1) | CA2877578A1 (enExample) |
| IN (1) | IN2014DN10669A (enExample) |
| WO (1) | WO2014006407A1 (enExample) |
| ZA (1) | ZA201409213B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9499510B2 (en) | 2012-07-03 | 2016-11-22 | Proximagen Limited | Pro-drug compounds |
| GB201304814D0 (en) * | 2013-03-15 | 2013-05-01 | Proximagen Ltd | Pro-drug compounds |
| GB201322934D0 (en) * | 2013-12-23 | 2014-02-12 | Proximagen Ltd | Prodrug compounds |
| GB201322932D0 (en) * | 2013-12-23 | 2014-02-12 | Proximagen Ltd | Pro-drug compounds |
| WO2016029191A2 (en) | 2014-08-22 | 2016-02-25 | Auckland Uniservices Limited | Channel modulators |
| US11717506B2 (en) | 2019-05-07 | 2023-08-08 | The Johns Hopkins University | Neuroprotective compounds for amyotrophic lateral sclerosis |
| US12667586B2 (en) | 2023-03-07 | 2026-06-30 | Glaukos Corporation | Treatments for ocular surface disorders |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0126311B1 (en) | 1983-05-18 | 1989-09-13 | Beecham Group Plc | Benzopyran derivatives. |
| DE3475786D1 (de) | 1983-09-01 | 1989-02-02 | Beecham Group Plc | Chromanol derivatives |
| EP0301713A3 (en) | 1987-07-07 | 1990-05-02 | Beecham Group Plc | Chroman derivatives for treatment of pulmonary hypertension |
| KR100326968B1 (ko) | 1992-12-11 | 2002-07-27 | 스미스클라인비이참피이엘시이 | 약학적 활성을 가진 이환식 화합물 |
| DE69327965T2 (de) | 1992-12-11 | 2000-10-19 | Smithkline Beecham Corp., Philadelphia | Pharmazeutische zusammenstellung enthaltende bizyklisch typ verbindungen |
| RO117094B1 (ro) | 1994-02-04 | 2001-10-30 | Smithkline Beecham Plc | Procedeu pentru epoxidarea enantioselectivă a olefinelor prochirale |
| DE69524871T2 (de) | 1994-06-10 | 2002-08-22 | Smithkline Beecham P.L.C., Brentford | Benzopyrans und deren verwendung als therapeutische mittel |
| GB9411635D0 (en) * | 1994-06-10 | 1994-08-03 | Smithkline Beecham Plc | Novel treatment |
| GB9813949D0 (en) | 1998-06-29 | 1998-08-26 | Smithkline Beecham Plc | Novel compounds |
| DE602005019210D1 (de) | 2004-12-23 | 2010-03-18 | Xenoport Inc | Von serinaminosäure abgeleitete prodrugs von propofol, zusammensetzungen, anwendungen und kristalline formen davon |
| WO2009147441A2 (en) | 2008-06-05 | 2009-12-10 | Minster Research Limited | Novel treatments |
| CA2726878A1 (en) | 2008-06-05 | 2009-12-10 | Minster Research Limited | Novel treatments |
| WO2011067607A1 (en) | 2009-12-03 | 2011-06-09 | Minster Research Ltd | Treatment of infectious diseases |
| EP2506846A1 (en) | 2009-12-03 | 2012-10-10 | Proximagen Limited | Treatment of allodynia and hyperalgesia |
| US9499510B2 (en) | 2012-07-03 | 2016-11-22 | Proximagen Limited | Pro-drug compounds |
| GB201304814D0 (en) | 2013-03-15 | 2013-05-01 | Proximagen Ltd | Pro-drug compounds |
-
2013
- 2013-07-03 US US14/410,234 patent/US9499510B2/en not_active Expired - Fee Related
- 2013-07-03 AU AU2013285164A patent/AU2013285164A1/en not_active Abandoned
- 2013-07-03 WO PCT/GB2013/051767 patent/WO2014006407A1/en not_active Ceased
- 2013-07-03 EP EP13735378.5A patent/EP2870148A1/en not_active Withdrawn
- 2013-07-03 US US13/934,665 patent/US20140011773A1/en not_active Abandoned
- 2013-07-03 CA CA2877578A patent/CA2877578A1/en not_active Abandoned
- 2013-07-03 IN IN10669DEN2014 patent/IN2014DN10669A/en unknown
-
2014
- 2014-12-15 ZA ZA2014/09213A patent/ZA201409213B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150322034A1 (en) | 2015-11-12 |
| IN2014DN10669A (enExample) | 2015-08-28 |
| WO2014006407A1 (en) | 2014-01-09 |
| EP2870148A1 (en) | 2015-05-13 |
| AU2013285164A1 (en) | 2015-01-22 |
| CA2877578A1 (en) | 2014-01-09 |
| US20140011773A1 (en) | 2014-01-09 |
| US9499510B2 (en) | 2016-11-22 |
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