ZA201308617B - Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections - Google Patents
Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infectionsInfo
- Publication number
- ZA201308617B ZA201308617B ZA2013/08617A ZA201308617A ZA201308617B ZA 201308617 B ZA201308617 B ZA 201308617B ZA 2013/08617 A ZA2013/08617 A ZA 2013/08617A ZA 201308617 A ZA201308617 A ZA 201308617A ZA 201308617 B ZA201308617 B ZA 201308617B
- Authority
- ZA
- South Africa
- Prior art keywords
- cancer
- prevention
- treatment
- diseases
- intracellular infections
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000003834 intracellular effect Effects 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F11/00—Rotary presses or machines having forme cylinders carrying a plurality of printing surfaces, or for performing letterpress, lithographic, or intaglio processes selectively or in combination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F13/00—Common details of rotary presses or machines
- B41F13/08—Cylinders
- B41F13/18—Impression cylinders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F13/00—Common details of rotary presses or machines
- B41F13/08—Cylinders
- B41F13/193—Transfer cylinders; Offset cylinders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F7/00—Rotary lithographic machines
- B41F7/02—Rotary lithographic machines for offset printing
- B41F7/025—Multicolour printing or perfecting on sheets or on one or more webs, in one printing unit
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F7/00—Rotary lithographic machines
- B41F7/02—Rotary lithographic machines for offset printing
- B41F7/04—Rotary lithographic machines for offset printing using printing units incorporating one forme cylinder, one transfer cylinder, and one impression cylinder, e.g. for printing on webs
- B41F7/06—Rotary lithographic machines for offset printing using printing units incorporating one forme cylinder, one transfer cylinder, and one impression cylinder, e.g. for printing on webs for printing on sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F7/00—Rotary lithographic machines
- B41F7/02—Rotary lithographic machines for offset printing
- B41F7/08—Rotary lithographic machines for offset printing using one transfer cylinder co-operating with several forme cylinders for printing on sheets or webs, e.g. sampling of colours on one transfer cylinder
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F9/00—Rotary intaglio printing presses
- B41F9/02—Rotary intaglio printing presses for multicolour printing
- B41F9/021—Sheet printing presses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mechanical Engineering (AREA)
- Oncology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161486728P | 2011-05-16 | 2011-05-16 | |
| PCT/US2012/037958 WO2012158699A1 (en) | 2011-05-16 | 2012-05-15 | Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201308617B true ZA201308617B (en) | 2020-07-29 |
Family
ID=47175068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2013/08617A ZA201308617B (en) | 2011-05-16 | 2013-11-15 | Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20120294831A1 (enExample) |
| EP (1) | EP2709453B1 (enExample) |
| JP (3) | JP6138764B2 (enExample) |
| KR (1) | KR102037162B1 (enExample) |
| CN (2) | CN103648282B (enExample) |
| AU (1) | AU2012255962B2 (enExample) |
| BR (1) | BR112013029505A2 (enExample) |
| CA (1) | CA2836253C (enExample) |
| DK (1) | DK2709453T3 (enExample) |
| EA (1) | EA024063B1 (enExample) |
| ES (1) | ES2767304T3 (enExample) |
| IL (1) | IL229459B (enExample) |
| MX (2) | MX2013013115A (enExample) |
| WO (1) | WO2012158699A1 (enExample) |
| ZA (1) | ZA201308617B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2709453T3 (da) * | 2011-05-16 | 2020-01-20 | Romark Laboratories Lc | Anvendelse af thiazolid-forbindelser til forebyggelse og behandling af virussygdomme, cancer og sygdomme forårsaget af intracellulære infektioner |
| KR20150139537A (ko) * | 2013-03-15 | 2015-12-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 수지상 세포의 반응 유전자 발현, 물질의 조성물 및 이의 사용 방법 |
| WO2015030504A1 (ko) * | 2013-09-02 | 2015-03-05 | 가톨릭대학교 산학협력단 | 비소세포폐암 치료제를 유효성분으로 포함하는 톡소포자충감염증의 예방 또는 치료용 약학 조성물 |
| KR101508611B1 (ko) | 2013-09-02 | 2015-04-08 | 가톨릭대학교 산학협력단 | 아파티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| KR101508610B1 (ko) * | 2013-09-02 | 2015-04-08 | 가톨릭대학교 산학협력단 | 다코미티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| CN107105660A (zh) | 2014-11-11 | 2017-08-29 | 罗马克实验室有限公司 | 使用替唑尼特、其类似物或盐的前药的治疗组合物和治疗方法 |
| WO2016123073A1 (en) * | 2015-01-26 | 2016-08-04 | Children's Medical Center Corporation | Treatment of infectious diseases |
| HK1250945A1 (zh) | 2016-03-31 | 2019-01-18 | 罗马克实验室有限公司 | 用於治疗病毒性感染的噻唑化物化合物 |
| PT3442580T (pt) | 2016-04-11 | 2020-12-23 | Genfit | Métodos de tratamento para doenças colestáticas e fibróticas |
| CN105998036B (zh) * | 2016-05-19 | 2018-07-27 | 洛阳市兽药厂 | 一种猪禽用复方磺胺硝唑尼特可溶性粉 |
| WO2018195035A1 (en) | 2017-04-18 | 2018-10-25 | Romark Laboratories L.C. | Inhibition of protein disulfide-isomerase a3 |
| CA3082859A1 (en) | 2017-11-17 | 2019-05-23 | Hubert Koster | [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate for use in lymphangioleiomyomatosis and other diseases |
| JP2022528727A (ja) * | 2019-04-12 | 2022-06-15 | ジェンフィット | 酸化ストレスに関連する疾患の治療に使用するためのニタゾキサニド及びチアゾリド |
| EP4003314B1 (en) | 2019-07-26 | 2024-07-10 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids useful for the prevention or treatment of disease |
| CN113398125B (zh) * | 2020-03-16 | 2024-05-03 | 绍兴君科臻元医药科技有限公司 | 替唑尼特药物组合物及其医药用途 |
| EP4182304A1 (en) | 2020-07-20 | 2023-05-24 | Romark Laboratories, L.C. | Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine |
| AU2021333566A1 (en) | 2020-08-24 | 2023-03-16 | Romark Laboratories L.C. | Use of thiazolides against coronaviruses |
| TW202245804A (zh) * | 2021-01-25 | 2022-12-01 | 美商艾斯佩維他治療學公司 | 官能化長鏈烴單羧酸及二羧酸及其衍生物以及其於預防或治療疾病之用途 |
| WO2022159808A2 (en) | 2021-01-25 | 2022-07-28 | Espervita Therapeutics, Inc. | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease |
| WO2023077711A1 (zh) * | 2021-11-03 | 2023-05-11 | 南方科技大学 | 预防前列腺癌的药剂的筛选方法及硝唑尼特在制药中的应用 |
| CN114231611A (zh) * | 2021-12-07 | 2022-03-25 | 中南大学湘雅二医院 | 干扰素诱导基因ifit3对b淋巴细胞活化及分化影响的研究方法 |
| CN116539887A (zh) * | 2023-01-09 | 2023-08-04 | 重庆医科大学 | Psme1作为药物靶点在筛选或制备治疗乙型肝炎的药物中的应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965590A (en) * | 1994-09-08 | 1999-10-12 | Romark Lab Lc | Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide |
| MX9604483A (es) | 1994-09-08 | 1998-02-28 | Jean-Francois Rossignol | Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas. |
| US5968961A (en) | 1997-05-07 | 1999-10-19 | Romark Laboratories, L.C. | Pharmaceutical compositions of tizoxanide and nitazoxanide |
| US5859038A (en) * | 1994-09-08 | 1999-01-12 | Romark Laboratories, L.C. | Method for treatment of helicobacter pylori infections |
| US5958038A (en) * | 1997-11-07 | 1999-09-28 | S3 Incorporated | Computer processor with two addressable memories and two stream registers and method of data streaming of ALU operation |
| US5935591A (en) | 1998-01-15 | 1999-08-10 | Romark Laboratories, L.C. | Method for treatment of equine protozoal myeloencephalitis with thiazolides |
| US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| UA90864C2 (en) | 2004-09-09 | 2010-06-10 | Ромарк Лебораториз, Л.К. | Halogenated benzamide derivatives |
| US20070015803A1 (en) | 2005-04-12 | 2007-01-18 | Romark Laboratories L.C. | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents |
| AP2907A (en) * | 2006-01-09 | 2014-05-31 | Romark Lab Lc | Viral hepatitis treatment |
| JP2011506290A (ja) * | 2007-12-06 | 2011-03-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | インフルエンザ組成物 |
| US20100081713A1 (en) * | 2008-03-19 | 2010-04-01 | CombinatoRx, (Singapore) Pte. Ltd. | Compositions and methods for treating viral infections |
| EP4209510B1 (en) * | 2008-12-09 | 2024-01-31 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| MX341877B (es) * | 2009-06-26 | 2016-09-06 | Romark Laboratories L C * | Compuestos y métodos para tratar influenza. |
| EP2467144A1 (en) * | 2009-07-24 | 2012-06-27 | ViroLogik GmbH | Combination of proteasome inhibitors and anti-hepatitis medication for treating hepatitis |
| MX2012004706A (es) * | 2009-10-22 | 2012-06-08 | Gilead Sciences Inc | Derivados de purina o deazapurina utiles para el tratamiento de (inter alia) infecciones virales. |
| US20110223131A1 (en) * | 2010-02-24 | 2011-09-15 | Gilead Sciences, Inc. | Antiviral compounds |
| US9439878B2 (en) * | 2010-06-03 | 2016-09-13 | Douglas Tyler McKenzie | Use of lumefantrine and related compounds in the treatment of cancer |
| EP2725902A4 (en) * | 2011-04-06 | 2015-06-24 | Univ Princeton | ANTIVIRAL COMBINATION THERAPY |
| DK2709453T3 (da) * | 2011-05-16 | 2020-01-20 | Romark Laboratories Lc | Anvendelse af thiazolid-forbindelser til forebyggelse og behandling af virussygdomme, cancer og sygdomme forårsaget af intracellulære infektioner |
-
2012
- 2012-05-15 DK DK12786263.9T patent/DK2709453T3/da active
- 2012-05-15 ES ES12786263T patent/ES2767304T3/es active Active
- 2012-05-15 WO PCT/US2012/037958 patent/WO2012158699A1/en not_active Ceased
- 2012-05-15 BR BR112013029505-8A patent/BR112013029505A2/pt active Search and Examination
- 2012-05-15 JP JP2014511457A patent/JP6138764B2/ja not_active Expired - Fee Related
- 2012-05-15 EP EP12786263.9A patent/EP2709453B1/en active Active
- 2012-05-15 AU AU2012255962A patent/AU2012255962B2/en not_active Ceased
- 2012-05-15 MX MX2013013115A patent/MX2013013115A/es unknown
- 2012-05-15 CN CN201280035142.0A patent/CN103648282B/zh not_active Expired - Fee Related
- 2012-05-15 EA EA201391616A patent/EA024063B1/ru not_active IP Right Cessation
- 2012-05-15 CN CN201611145115.5A patent/CN107096032A/zh active Pending
- 2012-05-15 CA CA2836253A patent/CA2836253C/en not_active Expired - Fee Related
- 2012-05-15 MX MX2018009061A patent/MX378726B/es unknown
- 2012-05-15 KR KR1020137031365A patent/KR102037162B1/ko not_active Expired - Fee Related
- 2012-05-15 US US13/471,948 patent/US20120294831A1/en not_active Abandoned
-
2013
- 2013-11-14 IL IL229459A patent/IL229459B/en active IP Right Grant
- 2013-11-15 ZA ZA2013/08617A patent/ZA201308617B/en unknown
-
2017
- 2017-04-26 JP JP2017087529A patent/JP2017149764A/ja not_active Withdrawn
-
2018
- 2018-01-03 US US15/861,234 patent/US10336058B2/en not_active Expired - Fee Related
- 2018-12-03 JP JP2018226678A patent/JP2019052175A/ja active Pending
-
2019
- 2019-06-12 US US16/438,783 patent/US10814612B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013013115A (es) | 2014-02-27 |
| JP2014513725A (ja) | 2014-06-05 |
| JP2017149764A (ja) | 2017-08-31 |
| EA024063B1 (ru) | 2016-08-31 |
| CN107096032A (zh) | 2017-08-29 |
| US10814612B2 (en) | 2020-10-27 |
| MX378726B (es) | 2025-03-11 |
| US20190291404A1 (en) | 2019-09-26 |
| IL229459B (en) | 2021-05-31 |
| JP6138764B2 (ja) | 2017-05-31 |
| AU2012255962B2 (en) | 2016-05-12 |
| US20180126722A1 (en) | 2018-05-10 |
| CN103648282A (zh) | 2014-03-19 |
| CA2836253A1 (en) | 2012-11-22 |
| EA201391616A1 (ru) | 2014-05-30 |
| EP2709453A4 (en) | 2014-11-19 |
| IL229459A0 (en) | 2014-01-30 |
| BR112013029505A2 (pt) | 2020-01-07 |
| ES2767304T3 (es) | 2020-06-17 |
| EP2709453A1 (en) | 2014-03-26 |
| KR20140028034A (ko) | 2014-03-07 |
| DK2709453T3 (da) | 2020-01-20 |
| US10336058B2 (en) | 2019-07-02 |
| JP2019052175A (ja) | 2019-04-04 |
| EP2709453B1 (en) | 2019-10-23 |
| KR102037162B1 (ko) | 2019-10-29 |
| WO2012158699A1 (en) | 2012-11-22 |
| CA2836253C (en) | 2021-02-16 |
| US20120294831A1 (en) | 2012-11-22 |
| CN103648282B (zh) | 2017-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL229459A0 (en) | Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer, and diseases caused by intracellular infections | |
| IL236700A (en) | History of alkylpyrimidine for the treatment of viral infections and other diseases | |
| ZA201501018B (en) | Compounds for the treatment of paramoxyvirus viral infections | |
| ZA201308746B (en) | Quinazoline derivatives for the treatment of viral infections and further diseases | |
| ZA201405820B (en) | Piperidino-pyrimidine derivatives for the treatment of viral infections | |
| ZA201502238B (en) | Acylaminopyrimidine derivatives for the treatment of viral infections and further diseases | |
| SI2943493T1 (sl) | Terapevtske spojine za zdravljenje virusnih infekcij | |
| HUE048561T2 (hu) | Pirimidinszármazékok vírusfertõzések kezelésére | |
| IL231217A0 (en) | Tetracyclic heterocyclic compounds and methods of using them in the treatment of viral diseases | |
| SG11201503231YA (en) | METHODS OF TREATING <i>S. AUREUS</i>-ASSOCIATED DISEASES | |
| IL235429A0 (en) | (r)-nifortal, its use in the treatment of infections and the preparation of (r) and (s)-nifortal | |
| IL238722A0 (en) | New annals of indole for the treatment of cancer, viral infections, and lung disease | |
| IL275636A (en) | Medical combination for cancer treatment | |
| EP2994156A4 (en) | Compounds, compositions and methods for the treatment of diseases through inhibiting tgf- activity | |
| IL234796B (en) | Compounds for the treatment of diseases related to ischemia-reperfusion | |
| ZA201306342B (en) | The treatment of viral infections | |
| EP2826486A4 (en) | PRODUCT FOR TREATING VIRAL HEPATITIS C | |
| ZA201407866B (en) | Composition for the prevention and treatment of viral infections caused by retroviruses | |
| HUE048301T2 (hu) | Új indolszármazékok rák, vírusfertõzések és tüdõbetegségek kezelésére |