ZA201209026B - 6-methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3,4-tetrahydropyrimidin-2-one derivatives as antitubercular agents - Google Patents

6-methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3,4-tetrahydropyrimidin-2-one derivatives as antitubercular agents

Info

Publication number
ZA201209026B
ZA201209026B ZA2012/09026A ZA201209026A ZA201209026B ZA 201209026 B ZA201209026 B ZA 201209026B ZA 2012/09026 A ZA2012/09026 A ZA 2012/09026A ZA 201209026 A ZA201209026 A ZA 201209026A ZA 201209026 B ZA201209026 B ZA 201209026B
Authority
ZA
South Africa
Prior art keywords
phenyl
tetrahydropyrimidin
carbamoyl
cycloalkyl
derivatives
Prior art date
Application number
ZA2012/09026A
Inventor
Dhiman Sarkar
Sampa Sarkar
Rohit Ramesh Joshi
Vijay Murlidhar Khedkar
Raghuvir Ramakant Pissurlenkar
Evans Cliffton Coutinho
Anamik Kantilal Shah
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Publication of ZA201209026B publication Critical patent/ZA201209026B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2012/09026A 2010-05-31 2012-11-29 6-methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3,4-tetrahydropyrimidin-2-one derivatives as antitubercular agents ZA201209026B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1244DE2010 2010-05-31
PCT/IB2011/001184 WO2011151701A1 (en) 2010-05-31 2011-05-31 6 - methyl - 4 - phenyl - 5 - ( phenyl or cycloalkyl) carbamoyl - 1,2,3, 4 - tetrahydropyrimidin- 2 - one derivatives as antitubercular agents

Publications (1)

Publication Number Publication Date
ZA201209026B true ZA201209026B (en) 2013-07-31

Family

ID=44532948

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/09026A ZA201209026B (en) 2010-05-31 2012-11-29 6-methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3,4-tetrahydropyrimidin-2-one derivatives as antitubercular agents

Country Status (5)

Country Link
CN (1) CN102971301B (en)
BR (1) BR112012030633A2 (en)
RU (1) RU2590163C2 (en)
WO (1) WO2011151701A1 (en)
ZA (1) ZA201209026B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2671688C2 (en) * 2013-02-27 2018-11-06 Каунсел Оф Сайентифик Энд Индастриал Рисёч Nitrite-reductase as potential anti-tubercular target and method to detect severity of tuberculosis
KR101656662B1 (en) * 2014-11-18 2016-09-12 한국생명공학연구원 Pharmaceutical composition containing 2-Oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide derivatives for prevention or treatment of metabolic disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2141322C1 (en) * 1997-08-12 1999-11-20 Голощапов Николай Михайлович Immunomodulating agent "izofon" showing antimycobacterial activity, method of its preparing and using
PL373412A1 (en) * 2002-05-09 2005-08-22 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods of their use for treating cellular proliferative diseases
WO2007101213A2 (en) * 2006-02-28 2007-09-07 Kalypsys, Inc. Novel 2-oxo-1,2,3,4-tetrahydropyrimidines, bicyclic pyrimidine diones and imidazolidine-2,4-diones useful as inducible nitric oxide synthase inhibitors

Also Published As

Publication number Publication date
RU2590163C2 (en) 2016-07-10
CN102971301A (en) 2013-03-13
WO2011151701A1 (en) 2011-12-08
BR112012030633A2 (en) 2016-08-16
CN102971301B (en) 2015-07-22
RU2012154338A (en) 2014-07-20

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