ZA201202416B - Combination - Google Patents
CombinationInfo
- Publication number
- ZA201202416B ZA201202416B ZA2012/02416A ZA201202416A ZA201202416B ZA 201202416 B ZA201202416 B ZA 201202416B ZA 2012/02416 A ZA2012/02416 A ZA 2012/02416A ZA 201202416 A ZA201202416 A ZA 201202416A ZA 201202416 B ZA201202416 B ZA 201202416B
- Authority
- ZA
- South Africa
- Prior art keywords
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25063509P | 2009-10-12 | 2009-10-12 | |
| PCT/US2010/052242 WO2011046894A1 (en) | 2009-10-12 | 2010-10-12 | Combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201202416B true ZA201202416B (en) | 2012-12-27 |
Family
ID=43876468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/02416A ZA201202416B (en) | 2009-10-12 | 2012-04-03 | Combination |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20120202822A1 (https=) |
| EP (1) | EP2488184A4 (https=) |
| JP (1) | JP2013507442A (https=) |
| KR (1) | KR20120097496A (https=) |
| CN (1) | CN102665720A (https=) |
| AU (1) | AU2010307043C1 (https=) |
| BR (1) | BR112012008519A2 (https=) |
| CA (1) | CA2777561A1 (https=) |
| EA (1) | EA020965B1 (https=) |
| IL (1) | IL219103A0 (https=) |
| MX (1) | MX2012004259A (https=) |
| WO (1) | WO2011046894A1 (https=) |
| ZA (1) | ZA201202416B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013545756A (ja) * | 2010-11-16 | 2013-12-26 | グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー２、リミテッド | 投与および治療方法 |
| JP6342396B2 (ja) | 2012-08-07 | 2018-06-13 | ノバルティス アーゲー | Ｂ−Ｒａｆ阻害薬、ＥＧＦＲ阻害薬及び場合によってはＰＩ３Ｋ−α阻害薬を含む組合せ医薬 |
| KR20190057421A (ko) | 2012-08-17 | 2019-05-28 | 에프. 호프만-라 로슈 아게 | 코비메티닙 및 베무라피닙을 투여함을 포함하는 흑색종의 조합 치료법 |
| CN103936728B (zh) * | 2013-01-18 | 2016-08-10 | 通化济达医药有限公司 | 噻唑激酶抑制剂 |
| CN103936730A (zh) * | 2013-01-22 | 2014-07-23 | 通化济达医药有限公司 | 苯磺酰胺噻唑激酶抑制剂 |
| CN103965180B (zh) * | 2013-01-24 | 2016-09-07 | 通化济达医药有限公司 | 苯磺酰胺噁唑和噻唑激酶抑制剂 |
| US20150352121A1 (en) * | 2013-03-12 | 2015-12-10 | Glaxosmithkline Llc | Combination |
| MA38522A1 (fr) | 2013-03-21 | 2017-10-31 | Novartis Ag | Thérapie de combinaison comprenant un inhibiteur de b-raf et un second inhibiteur. |
| WO2015003571A1 (zh) * | 2013-07-08 | 2015-01-15 | 杭州普晒医药科技有限公司 | 达拉菲尼甲磺酸盐的新晶型及其制备方法 |
| US11007183B2 (en) * | 2013-12-20 | 2021-05-18 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of PI3K/Akt pathway and ERK inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2349832A1 (en) * | 1999-01-13 | 2000-07-20 | Warner-Lambert Company | Benzenesulfonamide derivatives and their use as mek inhibitors |
| US8835473B2 (en) * | 2004-04-16 | 2014-09-16 | Rutgers, The State University Of New Jersey | Methods and compositions for treating cancer |
| US7691377B2 (en) * | 2004-04-16 | 2010-04-06 | Rutgers, The State University Of New Jersey | Methods and compositions for treating melanoma |
| WO2007084391A2 (en) * | 2006-01-18 | 2007-07-26 | Amgen Inc. | Thiazole compounds as protein kinase b ( pkb) inhibitors |
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| UA103319C2 (en) * | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
-
2010
- 2010-10-12 EP EP20100823916 patent/EP2488184A4/en not_active Withdrawn
- 2010-10-12 MX MX2012004259A patent/MX2012004259A/es active IP Right Grant
- 2010-10-12 KR KR1020127011760A patent/KR20120097496A/ko not_active Withdrawn
- 2010-10-12 US US13/501,387 patent/US20120202822A1/en not_active Abandoned
- 2010-10-12 CN CN2010800564396A patent/CN102665720A/zh active Pending
- 2010-10-12 JP JP2012534272A patent/JP2013507442A/ja not_active Ceased
- 2010-10-12 WO PCT/US2010/052242 patent/WO2011046894A1/en not_active Ceased
- 2010-10-12 BR BR112012008519A patent/BR112012008519A2/pt not_active IP Right Cessation
- 2010-10-12 CA CA2777561A patent/CA2777561A1/en not_active Abandoned
- 2010-10-12 EA EA201270537A patent/EA020965B1/ru not_active IP Right Cessation
- 2010-10-12 AU AU2010307043A patent/AU2010307043C1/en not_active Ceased
-
2012
- 2012-04-03 ZA ZA2012/02416A patent/ZA201202416B/en unknown
- 2012-04-05 IL IL219103A patent/IL219103A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2488184A1 (en) | 2012-08-22 |
| MX2012004259A (es) | 2012-05-29 |
| AU2010307043C1 (en) | 2014-03-13 |
| AU2010307043A1 (en) | 2012-05-17 |
| EP2488184A4 (en) | 2013-04-24 |
| JP2013507442A (ja) | 2013-03-04 |
| IL219103A0 (en) | 2012-06-28 |
| EA201270537A1 (ru) | 2012-12-28 |
| CA2777561A1 (en) | 2011-04-21 |
| BR112012008519A2 (pt) | 2016-04-05 |
| CN102665720A (zh) | 2012-09-12 |
| KR20120097496A (ko) | 2012-09-04 |
| AU2010307043B2 (en) | 2013-10-31 |
| EA020965B1 (ru) | 2015-03-31 |
| US20120202822A1 (en) | 2012-08-09 |
| WO2011046894A1 (en) | 2011-04-21 |
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