ZA201202363B - Mycobacterial vaccines - Google Patents

Mycobacterial vaccines

Info

Publication number
ZA201202363B
ZA201202363B ZA2012/02363A ZA201202363A ZA201202363B ZA 201202363 B ZA201202363 B ZA 201202363B ZA 2012/02363 A ZA2012/02363 A ZA 2012/02363A ZA 201202363 A ZA201202363 A ZA 201202363A ZA 201202363 B ZA201202363 B ZA 201202363B
Authority
ZA
South Africa
Prior art keywords
mycobacterial vaccines
mycobacterial
vaccines
Prior art date
Application number
ZA2012/02363A
Inventor
Alexandra Jane Spencer
Matthew Guy Cottingham
Adrian Vivian Sinton Hill
Fergal Hill
Original Assignee
Isis Innovation
Imaxio Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation, Imaxio Sa filed Critical Isis Innovation
Publication of ZA201202363B publication Critical patent/ZA201202363B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
ZA2012/02363A 2009-10-16 2012-04-02 Mycobacterial vaccines ZA201202363B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0918154.6A GB0918154D0 (en) 2009-10-16 2009-10-16 Mycobacterial vaccines
PCT/GB2010/051741 WO2011045612A1 (en) 2009-10-16 2010-10-15 Mycobacterial vaccines

Publications (1)

Publication Number Publication Date
ZA201202363B true ZA201202363B (en) 2013-01-30

Family

ID=41462453

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/02363A ZA201202363B (en) 2009-10-16 2012-04-02 Mycobacterial vaccines

Country Status (13)

Country Link
US (1) US9181311B2 (en)
EP (1) EP2488549B1 (en)
JP (1) JP2013507907A (en)
KR (1) KR20120083899A (en)
CN (1) CN102666575B (en)
AU (1) AU2010308120B2 (en)
BR (1) BR112012008790A2 (en)
CA (1) CA2776001A1 (en)
EA (1) EA201270517A1 (en)
GB (1) GB0918154D0 (en)
NZ (1) NZ599259A (en)
WO (1) WO2011045612A1 (en)
ZA (1) ZA201202363B (en)

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GB201006405D0 (en) 2010-04-16 2010-06-02 Isis Innovation Poxvirus expression system
EP3415919B1 (en) * 2012-02-07 2020-07-29 Intuitive Biosciences Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
KR20150058152A (en) * 2012-07-10 2015-05-28 트랜스진 에스아이 Mycobacterial antigen vaccine
CA2893120C (en) 2012-12-11 2022-03-15 Imaxio Modified coiled coil type proteins having improved properties
WO2014147087A1 (en) 2013-03-18 2014-09-25 Imaxio Influenza nucleoprotein vaccines
CN103290053A (en) * 2013-05-17 2013-09-11 中国人民解放军第四军医大学 Adenovirus vector of specific promoter of sialaden duct cell and construction method of adenovirus vector
US10266574B2 (en) * 2013-06-25 2019-04-23 International Aids Vaccine Initiative, Inc. Tuberculosis compositions and methods of using the same
TWI654200B (en) 2013-08-30 2019-03-21 環球免疫公司 Composition and method for treating or preventing tuberculosis
CN106029870A (en) * 2014-01-16 2016-10-12 凯利斯塔公司 Microorganisms for the enhanced production of amino acids and related methods
CN104805063A (en) * 2014-01-24 2015-07-29 中国人民解放军第三〇九医院 Mycobacterium tuberculosis latent infection related proteins, preparation and applications thereof
WO2015157561A1 (en) * 2014-04-09 2015-10-15 La Jolla Institute For Allergy And Immunology Specific and unique t cell responses and molecular signatures for treatment and diagnosis of mycobacterium tuberculosis
US10067147B2 (en) * 2014-08-29 2018-09-04 Centre National De La Recherche Scientifique (C.N.R.S.) Compositions useful in the diagnostic of latently infected Mycobacterium tuberculosis
WO2016154422A1 (en) 2015-03-24 2016-09-29 Fred Hutchinson Cancer Research Center Engineered and multimerized human immunodeficiency virus envelope glycoproteins and uses thereof
CN106237317A (en) * 2015-06-15 2016-12-21 复旦大学 The Vaccinum Calmette-Guerini being made up of antigen of mycobacterium tuberculosis
GB201513176D0 (en) * 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
CA3027995A1 (en) 2016-06-16 2017-12-21 Aeras Tuberculosis compositions and methods of treating or preventing tuberculosis
CN108239660B (en) * 2016-12-26 2021-08-10 上海生物制品研究所有限责任公司 Recombinant tuberculosis vaccine, preparation method and application thereof
TW201907937A (en) 2017-05-08 2019-03-01 美商葛利史東腫瘤科技公司 Alpha virus new antigen vector
WO2019144139A1 (en) * 2018-01-22 2019-07-25 Oregon State University Immunogenic compositions comprising mycobacterium bovis surface proteins and uses thereof
CN114072516A (en) 2019-05-30 2022-02-18 磨石生物公司 Modified adenoviruses
CN110240637A (en) * 2019-06-04 2019-09-17 华中农业大学 The immune-related molecular chaperone protein GroEL2 of Mycobacterium bovis and its encoding gene and application
KR102193304B1 (en) * 2019-10-24 2020-12-22 충남대학교산학협력단 Boosting composition for BCG vaccine comprising Rv2299c-ESAT6-HspX-RipA fusion protein
CN110724182B (en) * 2019-11-15 2022-04-08 上海交通大学 Marker combination for improving detection sensitivity of bacterial scrotum infection and application thereof
WO2021119545A1 (en) * 2019-12-11 2021-06-17 Gritstone Bio, Inc. Durable vaccination
CN116438308A (en) 2020-08-06 2023-07-14 磨石生物公司 Multi-epitope vaccine box
CN112979825A (en) * 2021-02-04 2021-06-18 兰州大学 Construction of mycobacterium tuberculosis fusion protein LT29, expression and purification method and application thereof
CN113999865B (en) * 2021-10-09 2023-06-16 安徽理工大学 Mycobacterium tuberculosis fusion protein AR2 and construction, expression and purification method and application thereof
CN116041543B (en) * 2022-12-07 2023-12-26 中国疾病预防控制中心传染病预防控制所 Mycobacterium tuberculosis multi-antigen fusion protein, encoding gene and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04506460A (en) * 1990-01-26 1992-11-12 バイオジェン，インコーポレイテッド C4 binding protein fusion protein
CN1284854C (en) * 2003-03-06 2006-11-15 钟森 Mosaic type DNA vaccine in use for preventing tuberculosis and immunological therapy
JP2007528210A (en) 2003-08-12 2007-10-11 アヴィディス エスアー Product comprising C4bp core protein and monomeric antigen and uses thereof
US20100278904A1 (en) * 2005-11-30 2010-11-04 Copenhagen University Nucleotide vaccine
EP1795540A1 (en) * 2005-11-30 2007-06-13 Imaxio Multimeric complexes of antigens and an adjuvant
GB0706912D0 (en) * 2007-04-10 2007-05-16 Isis Innovation Novel viral vaccines
CN101428143B (en) * 2008-12-09 2011-05-11 武汉大学 Attenuated bacteria vector tuberculosis vaccine carrying tuberculosis gene, preparation method and application thereof

Also Published As

Publication number Publication date
KR20120083899A (en) 2012-07-26
CN102666575A (en) 2012-09-12
EA201270517A1 (en) 2012-12-28
AU2010308120A1 (en) 2012-05-03
AU2010308120B2 (en) 2015-01-22
GB0918154D0 (en) 2009-12-02
US9181311B2 (en) 2015-11-10
CA2776001A1 (en) 2011-04-21
NZ599259A (en) 2014-03-28
CN102666575B (en) 2015-07-15
EP2488549A1 (en) 2012-08-22
US20120282290A1 (en) 2012-11-08
WO2011045612A1 (en) 2011-04-21
EP2488549B1 (en) 2015-07-29
BR112012008790A2 (en) 2019-09-24
JP2013507907A (en) 2013-03-07

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