ZA201103726B - Cancer treatments with radiation and immunocytokines - Google Patents

Cancer treatments with radiation and immunocytokines

Info

Publication number
ZA201103726B
ZA201103726B ZA2011/03726A ZA201103726A ZA201103726B ZA 201103726 B ZA201103726 B ZA 201103726B ZA 2011/03726 A ZA2011/03726 A ZA 2011/03726A ZA 201103726 A ZA201103726 A ZA 201103726A ZA 201103726 B ZA201103726 B ZA 201103726B
Authority
ZA
South Africa
Prior art keywords
immunocytokines
radiation
cancer treatments
treatments
cancer
Prior art date
Application number
ZA2011/03726A
Other languages
English (en)
Inventor
Thomas Wickham
Stephan G Klinz
Karl Josef Kallen
Ulrike Gnab-Vogt
Sylvia Holden
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA201103726B publication Critical patent/ZA201103726B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2011/03726A 2008-10-21 2011-05-20 Cancer treatments with radiation and immunocytokines ZA201103726B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10714608P 2008-10-21 2008-10-21
PCT/EP2009/007533 WO2010046097A1 (en) 2008-10-21 2009-10-21 Cancer treatments with radiation and immunocytokines

Publications (1)

Publication Number Publication Date
ZA201103726B true ZA201103726B (en) 2012-01-25

Family

ID=41510762

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/03726A ZA201103726B (en) 2008-10-21 2011-05-20 Cancer treatments with radiation and immunocytokines

Country Status (12)

Country Link
US (1) US20100330029A1 (enExample)
EP (1) EP2337579A1 (enExample)
JP (1) JP2012506394A (enExample)
KR (1) KR20110086101A (enExample)
CN (1) CN102196815A (enExample)
AU (1) AU2009306711A1 (enExample)
BR (1) BRPI0919857A2 (enExample)
CA (1) CA2741130A1 (enExample)
EA (1) EA201100626A1 (enExample)
MX (1) MX2011004193A (enExample)
WO (1) WO2010046097A1 (enExample)
ZA (1) ZA201103726B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015124297A1 (en) * 2014-02-19 2015-08-27 Merck Patent Gmbh Cancer-targeted il-12 immunotherapy
EP3596108A4 (en) 2017-03-15 2020-12-23 Pandion Operations, Inc. TARGETED IMMUNOTOLERANCE
US9861833B1 (en) * 2017-03-30 2018-01-09 Norman H. Anderson Methods of treating melanoma
JP2020521452A (ja) 2017-05-24 2020-07-27 パンディオン・セラピューティクス・インコーポレイテッド 標的化免疫寛容
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
US10174092B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
EP3972992A4 (en) 2019-05-20 2023-07-19 Pandion Operations, Inc. MADCAM TARGETED IMMUNOTLERANCE
WO2021168079A1 (en) 2020-02-21 2021-08-26 Pandion Operations, Inc. Tissue targeted immunotolerance with a cd39 effector
CN112768029B (zh) * 2020-12-27 2023-10-13 上海市东方医院（同济大学附属东方医院） 一种基于单细胞测序的组合用药推荐设备、方法及介质

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020110538A1 (en) * 1999-12-28 2002-08-15 Health Research, Inc. Methods and products for tumor immunotherapy using cytokines
PL358582A1 (en) * 2000-06-29 2004-08-09 Merck Patent Gmbh Enhancement of antibody-cytokine fusion protein mediated immune responses by combined treatment with immunocytokine uptake enhancing agents
EP2354791A1 (en) * 2001-12-04 2011-08-10 Merck Patent GmbH Immunocytokines with modulated selectivity
RU2007130552A (ru) * 2005-01-10 2009-02-20 Рисерч Дивелопмент Фаундейшн (US) Рекомбинантные молекулы направленного действия для лечения рака
CN101351475B (zh) * 2005-12-30 2013-05-15 默克专利有限公司 具有提高的稳定性的白细胞介素12p40变体

Also Published As

Publication number Publication date
US20100330029A1 (en) 2010-12-30
AU2009306711A1 (en) 2010-04-29
JP2012506394A (ja) 2012-03-15
CA2741130A1 (en) 2010-04-29
EP2337579A1 (en) 2011-06-29
CN102196815A (zh) 2011-09-21
BRPI0919857A2 (pt) 2015-12-15
MX2011004193A (es) 2011-05-24
KR20110086101A (ko) 2011-07-27
WO2010046097A1 (en) 2010-04-29
EA201100626A1 (ru) 2011-12-30

Similar Documents

Publication Publication Date Title
ZA201103726B (en) Cancer treatments with radiation and immunocytokines
ZA201101132B (en) Signatures and pcdeterminants associated with prostate cancer and methods of use thereof
EP2347233A4 (en) Non-contact medical thermometer with stray radiation shielding
ZA200807934B (en) Cancer treatments
GB0812753D0 (en) Electromagnetic radiation and its therapeutic effect
IL186662A0 (en) Combination cancer therapy with
ZA201001442B (en) Combination therapy with type i and type ii anti-cd20 antibodies
IL219992A0 (en) Combination therapy for treating cancer and dianostic assays for use therein
PT2167194T (pt) Tratamento do cancro utilizando campos electromagnéticos em combinação com terapia fotodinámica
ZA201004403B (en) Therapeutic cancer treatments
EP2324193A4 (en) ELECTROMAGNETIC RADIATION USING FORMAT TREATMENT
GB0819280D0 (en) Imgaing and radiotherapy methods
IL209361A0 (en) Combination therapy with pm00104 and another antitumor agent
ZA201005248B (en) 4-pyridinone compounds and their use for cancer
TWI365165B (en) Elevating mechanism and ferris wheel using the same
GB0804496D0 (en) Treating cancer
EP2150839A4 (en) Radiation sensor and dosimeter
IL199911A0 (en) 3-cinnolinecarboxamide derivatives and their use for treating cancer
GB2454562B (en) Bulb with adjustable radiation angle
EP2379097A4 (en) COMPOSITIONS AND METHOD FOR CANCER PREPARATION WITH CUPREDOXINES
EP2379098A4 (en) COMPOSITIONS AND METHODS FOR PREVENTING CANCER WITH CUPREDOXINS
WO2011008850A9 (en) H3k27me3 and cancer
PT2136631E (pt) Processos para tratamento da neoplasia com associação de agentes quimioterapêuticos e radiação
GB0809046D0 (en) Cancer treatment
IL208424A0 (en) Modified hydroxypolymer conjugates with bone seeking and tumor killing moieties